Protease Inhibitors and Phosphatase Inhibitors
Selleck Chemical LLC Mycophenolate Mofetil 50mg 128794-94-5 RS61443
Mycophenolate Mofetil (RS61443) is a non-competitive, selective and reversible inhibitor of inosine monophosphate dehydrogenase I/II with IC50 of 39 nM and 27 nM, respectively. Mycophenolate Mofetil induces caspase-dependent apoptosis and cell cycle inhibition in multiple myeloma cells. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
Cayman Chemical ENPP1 InhIbItr 43 5mg
An ENPP1 inhibitor (Ki = 41 nM); inhibits tumor growth in an LLC1 murine lung cancer model when administered orally or intravenously at doses of 10 and 100 mg/kg, respectively
Cayman Chemical FTase InhIbItr I 1mg
A potent and selective FTase inhibitor (IC50 = 21 nM); greater than 30-fold selective for FTase over GGTase (IC50 = 790 nM); prevents farnesylation of Ras; inhibits proliferation of cells transformed by Ras farnesylation; reduces GTP-Ras, decreases angiographic vasospasm, and improves clinical scores in a dog model of subarachnoid hemorrhage
Research Products International Corp Protease Inhibitor Cocktail III, Mammalian, 1 Vial
Mixture of six protease inhibitors for use with mammalian cells and tissue extracts.
Solubilized in 1 ml of DMSO. Will treat proteases extracted from 20g tissue.
One vial contains the following components:
Aprotinin: 80 uM
Bestatin: 5 mM
E-64: 1.5 mM
Leupeptin: 2 mM
Pepstatin A: 1 mM
Specificity: Serine Proteases, Cysteine Proteases, Trypsin like Proteases, Aspartic Proteases and Aminopeptidases
CPC Scientific Pyr-Pro-Pro-Gly-Gly-Ser-Lys-Val-Ile-Leu-Phe-OH (trifluoroacetate salt) 5MG
Morphogenic peptide (head activator) from hydra.ONE-LETTER SEQUENCE: Pyr-PPGGSKVILFMOLECULAR FORMULA: C54H84N12O14MOLECULAR WEIGHT:1125.33STORAGE CONDITIONS: -20 5C, CAS REGISTRY NUMBER: [79943-68-3], RESEARCH AREA: NeuropeptidesREFERENCES: C.Birr et al., FEBS Lett., 131, 317 (1981); H.C.Schaller and H.Bodenmueller, Naturwissenschaften, 68, 252 (1981); H.C.Schaller and H.Bodenmueller, Proc. Natl. Acad. Sci. USA, 78, 7000 (1981); H.Bodenmuller and H.C.Schaller, Nature, 293, 579 (1981); H.Bodenmueller, Nachr. Chem. Techn. Lab., 30, 263 (1982)
Cayman Chemical ThIordoxIn Rducts 1 InhIb 25mg
An irreversible inhibitor of TrxR1 (IC50 = 0.012 µM); inhibits TrxR1-induced reduction of Trx1 in a cell-free assay (IC50 = 4.3 µM); reduces the mitochondrial oxygen consumption rate in HCT116 cells at 10 µM; increases the intracellular levels of hydrogen peroxide in FaDu cancer cells in a time- and concentration-dependent manner; decreases the viability of FaDu cells (IC50 = 0.72 µM); decreases tumor growth in a FaDu HNSCC mouse xenograft model at 10 mg/kg twice per day; induces apoptosis in a FaDu HNSCC mouse xenograft model at 5 mg/kg daily; toxic to S. mansoni adult worms (LD50 = 10.07 µM)
Research Products International Corp RPI Leupeptin Hemisulfate, 50 Milligrams
Reversible inhibitor of cysteine and serine proteases resembling trypsin, Inhibits cathepsin B, kallikrein, papain, plasmin, thrombin and trypsin.
Working concentration: 1-10uM
Research Products International Corp RPI (-)-p-Bromotetramisole Oxalate, 25 Milligrams
Potent alkaline phosphate inhibitor. Mimics the action of orthovanadate in the potentiation of fluorouracil antiproliferative activity. Cell permeable.
Research Products International Corp PMSF, 250 G
Irreversible serine protease inhibitor of chymotrypsin, kallikrein, papain, subtilisin, thrombin and trypsin. Working Conentration: 0.1-1.0mM.
Cayman Chemical PI3KInase a InhIbItr 2hyd 10mg
An inhibitor of PI3K p110α (IC50 = 2 nM in an enzyme assay); selective for p110α over p110β, p110γ, and PI3K C2β (IC50s = 16, 660, and 220 nM, respectively); inhibits mTOR (IC50 = 49 nM); inhibits proliferation in A375 melanoma cells (IC50 = 0.58 μM)
Cayman Chemical Cdk1 InhIbItr 5mg
An inhibitor of Cdk1 (IC50 = 5.8 µM); selective for Cdk1 over Cdk5 and GSK3β (IC50s = 25 and >100 µM, respectively); inhibits HeLa cell proliferation (IC50 = 2 µM)
Chem-Impex International, Inc. Benzamidine hydrochloride hydrate | 206752-36-5 | MFCD00066285 | 25G
Benzamidine hydrochloride hydrate, 206752-36-5, MFCD00066285, 25G
Carbosynth LLC. CA-074 Me (5 mg vial), 1ea, MW: 397.47, Molecular formula: C19H31N3O6, CAS# 147859-80-1
Synonyms: [(2 S, 3S)-3-Propylcarbamoyloxirane-2-carbonyl]-l-isoleucyl-proline methyl ester; N-(L-3-trans-Propylcarbonyl-oxirane-2-carbonyl)-L-isoleucyl-L-proline methyl ester, Application: Proinhibitor for Intracellular Cathepsin B, Storage Temperature: -20°C, References: D.J. Buttle, M. Murata, C.G. Knight, and A.J. Barrett, Arch. Biochem. Biophys., 299, 377 (1992). (Original)