Protease Inhibitors and Phosphatase Inhibitors
MilliporeSigma™ Calbiochem™ PI 3-K inhibitor IX, PIK-90
The PI 3-K inhibitor IX, PIK-90, also referenced under CAS 677338-12-4, controls the biological activity of PI 3-K. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
MilliporeSigma™ Calbiochem™ p38 MAP Kinase Inhibitor XX, FGA-19
A cell-permeable compound that targets p38 C-terminal docking domain. Selectively inhibits MEF-2A phosphorylation by activated p38α (IC50 = 6.31μM)
MilliporeSigma™ Calbiochem™ ZK-756326
A highly potent and selective agonist for chemokine receptor 8 (CCR8) (IC50 values ar
MilliporeSigma™ Calbiochem™ p38 MAP Kinase Inhibitor XX, MW108
A cell-permeable, highly selective, active site targeted, stable inhibitor of neuronal p38 alpha MAP Kinase (Ki = 114 nM).
MilliporeSigma™ Calbiochem™ Cdc34 Inhibitor, CC0651
A cell-permeable, selective allosteric inhibitor of E2 ubiquitin-conjugating enzyme Cdc34 (IC50 = 2.5 μM in a Sic1-SCFCdc4 assay).
MilliporeSigma™ Calbiochem™ PIM1 Inhibitor II
The PIM1 Inhibitor II, also referenced under CAS 491871-58-0, controls the biological activity of PIM1. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
MilliporeSigma™ Calbiochem™ Endothall
A cell-permeable, specific inhibitor of protein phosphatase 2A (PP2A, IC50 = 90 nM).
MilliporeSigma™ Calbiochem™ VEGFR Tyrosine Kinase Inhibitor IV
The VEGFR Tyrosine Kinase Inhibitor IV, also referenced under CAS 475108-18-0, controls the biological activity of VEGFR Tyrosine Kinase. This small molecule/inhibitor is primarily used for Phosphorylation and Dephosphorylation applications.
MilliporeSigma™ Calbiochem™ Tpl2 Kinase Inhibitor II
The Tpl2 Kinase Inhibitor II, also referenced under CAS 1186649-59-1, controls the biological activity of Tpl2 Kinase. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
MilliporeSigma™ Calbiochem™ Dopamine Receptor Antagonist II, Thioridazine, HCl
The Dopamine Receptor Antagonist II, Thioridazine, HCl, also referenced under CAS 130-61-0, controls the biological activity of Dopamine Receptor. This small molecule/inhibitor is primarily used for Biochemicals applications.
MilliporeSigma™ Calbiochem™ COX-2 Inhibitor III
The COX-2 Inhibitor III, also referenced under CAS 1177728-24-3, controls the biological activity of COX-2. This small molecule/inhibitor is primarily used for Cell Signaling applications.
MilliporeSigma™ Calbiochem™ PKM2 Activator III
A cell-permeable quinoline-sulfonamide that acts as a potent allosteric PKM2 activator both in cell-free enzymatic assays (AC50 = 17nM with 40 ng PKM2/200μL) and in cultures (AC50 = 45nM in A549 cells) via a high affinity, 2:1 stoichiometric binding, effectively locking PKM2 in an active tetrameric state resistant to known intracellular negative regulators of FBP-activated PKM2 te
MilliporeSigma™ Calbiochem™ Okadaic Acid, Prorocentrum sp.
Okadaic Acid, CAS 78111-17-8, is a highly potent inhibitor of protein phosphatase 1 (IC50 = 10-15 nM) and 2A (IC50 = 0.1 nM).
MilliporeSigma™ Calbiochem™ InSolution™ TLR4 Inhibitor, TAK-242
A 25 mM (2 mg/221 μL) sterile-filtered solution of TLR4 Inhibitor, TAK-242 in DMSO.