Protease Inhibitors and Phosphatase Inhibitors
MilliporeSigma™ Calbiochem™ Plasminogen Activator Inhibitor-1, Mutant, Human, Recombinant
Primarily used for Protease Inhibitors applications.
MilliporeSigma™ Calbiochem™ InSolution™ γ-Secretase Inhibitor IX
InSolution™ g-Secretase Inhibitor IX, CAS 208255-80-5, is a 25 mM (5 mg/462 μl or 10 mg/924 μl) solution of g-secretase Inhibitor IX (DAPT; Cat. No. 565770) in DMSO.
MilliporeSigma™ Calbiochem™ β-Secretase Substrate VI, Fluorogenic
A highly selective, fluorescence resonance energy transfer (FRET) peptide substrate for β-secretase (BACE); (pH ∽4.0, k
MilliporeSigma™ Calbiochem™ Ro-31-7549, Monohydrate
A cell permeable, reversible, selective protein kinase C (PKC) inhibitor (IC50 = 158 nM for rat brain PKC) that acts at the ATP binding site of PKC.
MilliporeSigma™ Calbiochem™ Rho Kinase Inhibitor III, Rockout
The Rho Kinase Inhibitor III, Rockout, also referenced under CAS 7272-84-6, controls the biological activity of Rho Kinase. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
MilliporeSigma™ Calbiochem™ SB 202190, Hydrochloride
A water-soluble form of the potent p38 MAP kinase inhibitor SB 202190.
MilliporeSigma™ Calbiochem™ Phorbol-12-myristate-13-acetate
Phorbol-12-myristate-13-acetate, CAS 16561-29-8, is the most common phorbol ester. Activates PKC at nanomolar concentrations.
MilliporeSigma™ Calbiochem™ Phosphatase Inhibitor Cocktail Set I
Phosphatase Inhibitor Cocktail Set I contains three inhibitors that will inhibit alkaline phosphatases as well as serine/threonine protein phosphatases such as PP1 and PP2A.
MilliporeSigma™ Calbiochem™ SU1498
A potent, reversible, ATP-competitive and selective inhibitor of Flk-1 kinase (IC50 = 700 nM), a vascular endothelial growth factor (VEGF) receptor kinase.
MilliporeSigma™ Calbiochem™ InSolution™ γ-Secretase Inhibitor X
InSolution™ γ-Secretase Inhibitor X is a 1 mM solution in DMSO. A highly potent inhibitor of g-secretase (IC50 = 17, 48, 67 nM for Aβtotal, Aβ40 & Aβ42 in SHSY5Y cells overexpressing spβA4CTF).
MilliporeSigma™ Calbiochem™ Paclitaxel, Semi-Synthetic
A semi-synthetic form of Paclitaxel having no contamination by natural taxanes. Also has reduced levels of epimerization products as contaminants.
MilliporeSigma™ Calbiochem™ InSolution™ PD 98059
InSolution™ PD 98059, CAS 167869-21-8, is a 5mg/mL solution in DMSO. A a cell-permeable, selective and reversible inhibitor of MAP Kinase Kinase (MEK).
MilliporeSigma™ Calbiochem™ 4α-Phorbol-12,13-didecanoate
Inactive on mouse skin as an inflammatory and tumor-promoting agent.
MilliporeSigma™ Calbiochem™ Protease Inhibitor Cocktail Set III, Animal-Free
Protease Inhibitor Cocktail Set III, Animal-Free, is a cocktail of six protease inhibitors with broad specificity for the inhibition of aspartic, cysteine & serine proteases & aminopeptidases.
MilliporeSigma™ Calbiochem™ Proteasome Inhibitor Set II
The Proteasome Inhibitor Set II controls the biological activity of Proteasome. This small molecule/inhibitor is primarily used for Protease Inhibitors applications.