Protease Inhibitors and Phosphatase Inhibitors
MilliporeSigma™ Calbiochem™ InSolution™ Necrostatin-1
A cell-permeable, potent, and selective blocker of necroptosis (EC50 = 494nM in FADD-deficient Jurkat cells treated with TNF-α), a nonapoptotic necrotic cell death pathway mediated by death-domain receptors (DRs) that offers neuroprotection in a murine model of ischemic brain inj
MilliporeSigma™ Calbiochem™ Apamin, Bee Venom
Polypeptide neurotoxin known to pass through the blood-brain barrier.
MilliporeSigma™ Calbiochem™ Opn4 Antagonist
Prevents melanopsin/Opn4 photoactivation in a reversible manner. Inhibits cellular phototransduction mediated by human Opn4 (IC50 = 665 nM; using CHO transfectants).
MilliporeSigma™ Calbiochem™ NF-κB SN50M, Cell-Permeable Inactive Control Peptide
An inactive control for SN50 peptide.
MilliporeSigma™ Calbiochem™ Histone Deacetylase Inhibitor III
The Histone Deacetylase Inhibitor III, also referenced under CAS 251456-60-7, controls the biological activity of Histone Deacetylase. This small molecule/inhibitor is primarily used for Cell Structure applications.
MilliporeSigma™ Calbiochem™ AG 538
A potent, cell-premeable, reversible, and competitive inhibitor of IGF-1 receptor kinase (IC50 = 400 nM).
MilliporeSigma™ Calbiochem™ SKF-525A, Hydrochloride
Cell permeable. Blocks glibenclamide-sensitive K+ channels. Inhibits neuronal nitric oxide synthase. Also inhibits hepatic drug metabolism by inhibiting the cytochrome P450 system.
MilliporeSigma™ Calbiochem™ Protease Inhibitor Cocktail Set II
The Protease Inhibitor Cocktail Set II controls the activity of Protease. This small molecule/inhibitor is primarily used for Protease Inhibitors applications.
MilliporeSigma™ Calbiochem™ BLM Helicase Inhibitor, ML216
A cell-permeable pyridinyl-thiadiazolylurea compound that selectively blocks Bloom's syndrome protein (BLM) helicase activity of both full-length as well as truncated BLM636-1298 forms (IC50
MilliporeSigma™ Calbiochem™ Wnt Antagonist III, Box5
The Wnt Antagonist III, Box5 controls the biological activity of Wnt. This small molecule/inhibitor is primarily used for Cancer applications.
MilliporeSigma™ Calbiochem™ Deltamethrin
Synthetic type II pyrethroid. Potent inhibitor of calcineurin. Causes an increase in neurotransmitter release at synapses, and increases intrasynaptosomal Ca2+ levels.
MilliporeSigma™ Calbiochem™ PI 3-Kα Inhibitor IV
The PI 3-Kα Inhibitor IV, also referenced under CAS 1188890-32-5, controls the biological activity of PI 3-Kα. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
MilliporeSigma™ Calbiochem™ Amyloid Precursor Protein β-Secretase Inhibitor
The Amyloid Precursor Protein β-Secretase Inhibitor controls the biological activity of Amyloid Precursor Protein β-Secretase. This small molecule/inhibitor is primarily used for Neuroscience applications.
MilliporeSigma™ Calbiochem™ IP6K Inhibitor
The IP6K Inhibitor, also referenced under CAS 519178-28-0, controls the biological activity of IP6K.
MilliporeSigma™ Calbiochem™ MPNST Inhibitor, Cpd21
A cell-permeable. Reversible, selective inhibitor of the growth of malignant peripheral nerve sheath tumors (EC50 = 439 nM, 754 nM, and 1.0 μM in S462, SNF96.2, and sMPNST cells).