Protease Inhibitors and Phosphatase Inhibitors
MilliporeSigma™ Calbiochem™ Wnt Antagonist I, IWR-1-endo
Wnt Antagonist I, IWR-1-endo, is a cell-permeable inhibitor of TNKS1/PARP5a (IC50 = 131 nM) & TNKS2/PARP5b (IC50≥ 56 nM). Suppress Wnt-stimulated transcription activity (IC50 = 180 nM).
MilliporeSigma™ Calbiochem™ JNK Inhibitor II, Negative Control
The JNK Inhibitor II, Negative Control, also referenced under CAS 54642-23-8, controls the biological activity of JNK. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
MilliporeSigma™ Calbiochem™ Cyclophilin A Inhibitor
The Cyclophilin A Inhibitor, also referenced under CAS 1186372-20-2, controls the biological activity of Cyclophilin A. This small molecule/inhibitor is primarily used for Inflammation/Immunology applications.
MilliporeSigma™ Calbiochem™ Phenylmethylsulfonyl Fluoride
Phenylmethylsulfonyl Fluoride, CAS 329-98-6, is an irreversible inhibitor of serine proteases. It causes sulfonylation of the active-site serine residues.
MilliporeSigma™ Calbiochem™ Adenosine A2A Receptor Antagonist II, SCH-58261
A highly potent and selective antagonist of adenosine A2A receptor (Ki = 6
MilliporeSigma™ Calbiochem™ MK2a Inhibitor
The MK2a Inhibitor, also referenced under CAS 41179-33-3, controls the biological activity of MK2a. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
MilliporeSigma™ Calbiochem™ 2,3 cis-Piperidine dicarboxylic acid
A non-specific antagonist of NMDA, AMPA and kainate ionotropic receptors and a partial agonist for NMDA receptors.
MilliporeSigma™ Calbiochem™ Wortmannin
Wortmannin, CAS 19545-26-7, is a cell-permeable, potent, selective, and irreversible inhibitor of PI3-Kinase (IC50 = 5 nM). Does not affect any upstream signaling events.
MilliporeSigma™ Calbiochem™ Wnt/β-catenin Inhibitor, Cardamonin
The Wnt/β-catenin Inhibitor, Cardamonin, also referenced under CAS 19309-14-9, controls the biological activity of Wnt/β-catenin. This small molecule/inhibitor is primarily used for Cancer applications.
MilliporeSigma™ Calbiochem™ InSolution™ Akt Inhibitor VIII, Isozyme-Selective, Akti-1/2
The InSolution™ Akt Inhibitor VIII, Isozyme-Selective, Akti-1/2 controls the biological activity of Akt.
MilliporeSigma™ Calbiochem™ SB 242084 Hydrochloride
A selective, brain-penetrant 5-HT2C receptor antagonist (pK
MilliporeSigma™ Calbiochem™ RSK Inhibitor, SL0101
The RSK Inhibitor, SL0101 controls the biological activity of RSK. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
MilliporeSigma™ Calbiochem™ PERK Inhibitor II, GSK2656157
PERK Inhibitor II, GSK2656157, CAS 1337532-29-2 is a cell-permeable, potent, ATP-competitive inhibitor of PERK/EIF2AK3 (IC50 = 0.9nM).
MilliporeSigma™ Calbiochem™ MMP-2/MMP-9 Substrate I, Fluorogenic
A fluorogenic substrate for both the 72 kDa human fibroblast gelatinase (HFG; MMP-2) and the 92 kDa human neutrophil gelatinase (HNG; MMP-9).
MilliporeSigma™ Calbiochem™ SOD1 Inhibitor, LCS-1
The SOD1 Inhibitor, LCS-1, also referenced under CAS 41931-13-9, controls the biological activity of SOD1.