Protease Inhibitors and Phosphatase Inhibitors
MilliporeSigma™ Calbiochem™ 1-Aminocyclopropane-1-carboxylic Acid
An agonist for the glycine modulatory site of the N-methyl-D-aspartate (NMDA) receptor complex.
MilliporeSigma™ Calbiochem™ β-Secretase Inhibitor IV
β-Secretase Inhibitor IV, CAS 797035-11-1, is a cell-permeable inhibitor that binds to BACE-1 active site and blocks its proteolytic activity (IC50 = 15 nM for human BACE-1).
MilliporeSigma™ Calbiochem™ 15-PGDH Inhibitor
The 15-PGDH Inhibitor controls the biological activity of 15-PGDH. This small molecule/inhibitor is primarily used for Membrane applications.
MilliporeSigma™ Calbiochem™ Aurora Kinase/Cdk Inhibitor
The Aurora Kinase/Cdk Inhibitor, also referenced under CAS 443797-96-4, controls the biological activity of Aurora Kinase/Cdk. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
MilliporeSigma™ Calbiochem™ REST Inhibitor, X5050
A cell-permeable inhibitor repressor element-1 silencing transcription factor (REST). Targets REST degradation, but not its expression or binding to repressor element binding sequence.
MilliporeSigma™ Calbiochem™ Splitomicin
A cell-permeable lactone derived from β-naphthol that acts as a selective inhibitor of NAD+-dependent histone deacetylase activity of Sir2 protein (IC50 = 60 μM).
MilliporeSigma™ Calbiochem™ InSolution™ Cdk1 Inhibitor IV, RO-3306
The InSolution™ Cdk1 Inhibitor IV, RO-3306 controls the biological activity of Cdk1. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
MilliporeSigma™ Calbiochem™ Genistin
An isoflavone glycoside found in soy-based food products.
MilliporeSigma™ Calbiochem™ Tubulin Polymerization Inhibitor II
The Tubulin Polymerization Inhibitor II, also referenced under CAS 1151995-69-5, acts as an effective anti-microtubule agent. This small molecule/inhibitor is primarily used for Cell Structure applications.
MilliporeSigma™ Calbiochem™ Calpain Inhibitor IV
The Calpain Inhibitor IV controls the biological activity of Calpain. This small molecule/inhibitor is primarily used for Protease Inhibitors applications.
MilliporeSigma™ Calbiochem™ 2,3 cis-Piperidine dicarboxylic acid
A non-specific antagonist of NMDA, AMPA and kainate ionotropic receptors and a partial agonist for NMDA receptors.
MilliporeSigma™ Calbiochem™ InSolution™ KN-93
A cell-permeable, competitive inhibitor of Ca2+/calmodulin-dependent protein kinase II (Ki = 370nM)
MilliporeSigma™ Calbiochem™ Gambogic Acid, Garcinia hanburyi
A cell-permeable caspase activator and an apoptosis inducer that was originally isolated from gamboge resin for its antimicrobial properties.
MilliporeSigma™ Calbiochem™ WRN Helicase Inhibitor, NSC 19630
The WRN Helicase Inhibitor, NSC 19630, also referenced under CAS 72835-26-8, controls the biological activity of WRN Helicase. This small molecule/inhibitor is primarily used for Cell Signaling applications.
MilliporeSigma™ Calbiochem™ Wiskostatin
A cell-permeable N-alkylated carbazole derivative that selectively blocks actin filament assembly.