Protease Inhibitors and Phosphatase Inhibitors
MilliporeSigma™ Calbiochem™ SRPK Inhibitor, SRPIN340
A cell-permeable isonicotinamide that acts as an ATP-competitive SRPK1-selective inhibitor (IC50
MilliporeSigma™ Calbiochem™ Estrogen Receptor Antagonist, ICI 182,780
A cell-permeable estrogen antagonist. More effective than tamoxifen in reducing estrogen receptors in breast tumor cells.
MilliporeSigma™ Calbiochem™ InSolution™ AG490
Potent inhibitor of epidermal growth factor receptor kinase autophosphorylation (IC50 = 100nM)
MilliporeSigma™ Calbiochem™ Bcr-abl Inhibitor III, GNF-5
The Bcr-abl Inhibitor III, GNF-5 controls the biological activity of Bcr-abl. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
MilliporeSigma™ Calbiochem™ REST Inhibitor, X5050
A cell-permeable inhibitor repressor element-1 silencing transcription factor (REST). Targets REST degradation, but not its expression or binding to repressor element binding sequence.
MilliporeSigma™ Calbiochem™ NFAT Inhibitor
The NFAT Inhibitor controls the biological activity of NFAT. This small molecule/inhibitor is primarily used for Inflammation/Immunology applications.
MilliporeSigma™ Calbiochem™ InSolution™ Aphidicolin
A 30 mM (1 mg/98 μL) sterile-filtered solution of Aphidicolin in DMSO.
MilliporeSigma™ Calbiochem™ MDL-12,330A, Hydrochloride
Cell-permeable and irreversible inhibitor of adenylate cyclase (IC50 = 250 μM).
MilliporeSigma™ Calbiochem™ InSolution™ Y-27632, Sterile-Filtered, Cell Culture-Tested
A 10 mM (2 mg/591 μL) sterile-filtered solution of Y-27632 in H2O.
MilliporeSigma™ Calbiochem™ HNF4 Antagonist, BI6015
The HNF4 Antagonist, BI6, also referenced under CAS 93987-29-2, controls the biological activity of HNF4.
MilliporeSigma™ Calbiochem™ LFM-A13
A potent, cell-permeable, reversible, substrate competitive, and specific inhibitor of Bruton's Tyrosine Kinase (BTK; IC50 = 17.2μM for human BTK
MilliporeSigma™ Calbiochem™ Cdc25 Inhibitor IV, NSC 95397
The Cdc25 Inhibitor IV, NSC 95397, also referenced under CAS 93718-83-3, controls the biological activity of Cdc25. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
MilliporeSigma™ Calbiochem™ Casein Kinase II Inhibitor I
The Casein Kinase II Inhibitor I, also referenced under CAS 17374-26-4, controls the biological activity of Casein Kinase II. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
MilliporeSigma™ Calbiochem™ Indomethacin
A non-steroidal anti-inflammatory, cell permeable, antipyretic agent.
MilliporeSigma™ Calbiochem™ Picrotoxin, Anamirta cocculin
A potent antagonist of GABA receptors (IC50 = 240 nM) at synapses in the central nervous system.