Protease Inhibitors and Phosphatase Inhibitors
MilliporeSigma™ Calbiochem™ Heat Shock Factor 1 Inhibitor, KRIBB11
The Heat Shock Factor 1 Inhibitor, KRIBB11 controls the biological activity of Heat Shock Factor 1.
MilliporeSigma™ Calbiochem™ 3-Isobutyl-1-methylxanthine
A cell-permeable, non-specific inhibitor of cAMP and cGMP phosphodiesterases (IC50 = 2-50 μM).
MilliporeSigma™ Calbiochem™ Simvastatin
A lipophilic 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitor that blocks Ras function through inhibition of farnesylation.
MilliporeSigma™ Calbiochem™ Caspase Inhibitor II
The Caspase Inhibitor II, also referenced under CAS 147837-52-3, controls the biological activity of Caspase. This small molecule/inhibitor is primarily used for Cancer applications.
MilliporeSigma™ Calbiochem™ U-73343
A cell-permeable analog of U-73122 that acts as a very weak inhibitor of phospholipase C. Suitable as a negative control.
MilliporeSigma™ Calbiochem™ NFAT Activation Inhibitor III
The NFAT Activation Inhibitor III, also referenced under CAS 3519-82-2, controls the biological activity of NFAT. This small molecule/inhibitor is primarily used for Inflammation/Immunology applications.
MilliporeSigma™ Calbiochem™ γ-Secretase Substrate, Fluorogenic
An internally quenched fluorogenic peptide substrate containing the C-terminal β-APP (amyloid β-peptide precursor protein) amino acid sequence that is cleaved by γ-secretase.
MilliporeSigma™ Calbiochem™ Pepstatin A, Penetratin
A Pepstatin A that is ≈75% less potent against Cathespins D/E than PepA in cell-free assays.
MilliporeSigma™ Calbiochem™ InSolution™ Roscovitine
A potent and selective inhibitor of cyclin-dependent kinases (Cdks)
MilliporeSigma™ Calbiochem™ Ellagic Acid, Dihydrate
A cell-permeable, reversible, potent antioxidant that has anti-mutagenic and anti-carcinogenic properties.
![MilliporeSigma™ Calbiochem™ Forskolin, 7-Deacetyl-7-[O-(N-methylpiperazino)-γ-butyryl]-, Dihydrochloride](https://assets.fishersci.com/TFS-Assets/CCG/product-images/F584162~p.eps-250.jpg)
MilliporeSigma™ Calbiochem™ Forskolin, 7-Deacetyl-7-[O-(N-methylpiperazino)-γ-butyryl]-, Dihydrochloride
Chemically-modified forskolin with greater stability and water solubility than the parent compound.
MilliporeSigma™ Calbiochem™ Nα-Benzyloxycarbonyl-L-lysine Thiobenzyl Ester, Hydrochloride
Highly sensitive substrate for trypsin-like enzymes and granule-associated serine esterase.
MilliporeSigma™ Calbiochem™ (-)-Cytisine
A potent agonist selective for neuronal nAChRs (Ki = 2, 5890, 480, 329, and 492nM at α4β2, α7, α3β4, α6/α4β4, α1β1γδ, respective
MilliporeSigma™ Calbiochem™ PDE4D Inhibitor, GEBR-7b
The PDE4D Inhibitor, GEBR-7b controls the biological activity of PDE4D. This small molecule/inhibitor is primarily used for Cell Signaling applications.
MilliporeSigma™ Calbiochem™ Purmorphamine
A cell-permeable activator of Hedgehog signaling that induces osteoblast differentiation of multipotent mesenchymal progenitor cells C3H10T1/2 (EC50 = 1 μM).