Protease Inhibitors and Phosphatase Inhibitors
MilliporeSigma™ Calbiochem™ Glyburide
A sulfonylurea that selectively blocks ATP-sensitive K+ channels.
MilliporeSigma™ Calbiochem™ HIF Inhibitor V
A cell-permeable phenoxyacrylamido compound that inhibits hypoxia-induced cellular HIF-1α accumulation in a manner similar to LW6 (Cat
MilliporeSigma™ Calbiochem™ CXCR4 Antagonist IV, TF14016
A 14-aa internally disulfide-bonded peptide that potently competes against SDF-1α/CXCL12 for CXCR4 binding (IC50
MilliporeSigma™ Calbiochem™ Stauprimide
A cell-permeable ESCs (Embryonic Stem Cells) EMT (Epithelial-Mesenchymal Transition) inducer that is reported to prime/sensitize human and murine ESC cultures for much more enhanced/efficient differentiation into progenitor cells of multiple lineages.
MilliporeSigma™ Calbiochem™ Glutaminase Inhibitor II, BPTES
A cell-permeable, potent, selective, reversible, and uncompetitive allosteric inhibitor of kidney-type glutaminase (GLS1). Does not affect the activity of liver glutaminase.
MilliporeSigma™ Calbiochem™ PKC Inhibitor Set
The PKC Inhibitor Set controls the biological activity of PKC. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
MilliporeSigma™ Calbiochem™ ERO1 Inhibitor II, EN460
A cell-permeable thiol reactive enone (EN) compound that selectively interacts with the active-site cysteine of reduced, active form of ERO1α and inhibits its activity (IC50
MilliporeSigma™ Calbiochem™ InSolution™ SB 203580
InSolution SB 203580, CAS 152121-47-6, is a 1mg/mL solution of SB 203580 in DMSO. A cell-permeable, selective, reversible inhibitor of p38 MAP kinase (IC50 = 34nM in vitro, 600nM in cells).
MilliporeSigma™ Calbiochem™ S-Methyl-L-thiocitrulline, Dihydrochloride
A cell-permeable inhibitor of nitric oxide synthase that exhibits about 17-fold greater selectivity for rat neuronal nitric oxide synthase (IC50 = 300nM) compared to the endothelial enzyme (IC50 = 5.4μM).
MilliporeSigma™ Calbiochem™ TRPC3 Channel Inhibitor, Pyr3
The TRPC3 Channel Inhibitor, Pyr3, also referenced under CAS 1160514-60-2, controls the biological activity of TRPC3 Channel. This small molecule/inhibitor is primarily used for Protease Inhibitors applications.
MilliporeSigma™ Calbiochem™ Kifunensine, Kitasatosporia kifunense
A potent alkaloid inhibitor of mannosidase I.
MilliporeSigma™ Calbiochem™ 5,6-Dichloro-1-β-D-ribofuranosylbenzimidazole
A potent, ATP-competitive, and specific inhibitor of casein kinase II (IC50 = 6 μM).
MilliporeSigma™ Calbiochem™ TRPM4 inhibitor, 9-Phenanthrol
The TRPM4 inhibitor, 9-Phenanthrol, also referenced under CAS 484-17-3, controls the biological activity of TRPM4. This small molecule/inhibitor is primarily used for Biochemicals applications.
MilliporeSigma™ Calbiochem™ Melatonin
A hormone that has been postulated as the mediator of photo-induced anti-gonadotropic activity in photoperiodic mammals.
MilliporeSigma™ Calbiochem™ Isoproterenol, Hydrochloride
Phenethylamine derivative.