Protease Inhibitors and Phosphatase Inhibitors
MilliporeSigma™ Calbiochem™ Antithrombin III, Human Plasma
Single-chain glycoprotein present in normal serum at about 23mg/100 ml.
MilliporeSigma™ Calbiochem™ VEGFR2 Kinase Inhibitor VII, SKLB1002
The VEGFR2 Kinase Inhibitor VII, SKLB1002 controls the biological activity of VEGFR2 Kinase. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
MilliporeSigma™ Calbiochem™ Erastin
A cell-permeable piperazinyl-quinazolinone compound that exhibits oncogene-selective lethality.
MilliporeSigma™ Calbiochem™ Purvalanol A
A potent, cell-permeable, reversible, and selective inhibitor of cyclin-dependent kinases.
MilliporeSigma™ Calbiochem™ HMTase Inhibitor IX, MM-102
A cell-permeable peptidomimetic that prevents MLL1 (Mixed Lineage Leukemia 1) from complex assembling with WDR5 (Trp-Asp Repeat Domain 5), RbBP5 (Retinoblastoma Binding Protein 5), and ASH2L (Absent Small or Homeotic-2-Like) for enhanced H3K4 methyltransferase activity (IC50
MilliporeSigma™ Calbiochem™ Gö 6976
Gö 6976, CAS 136194-77-9, is a cell-permeable, reversible, and ATP-competitive inhibitor of PKC (IC50 = 7.9 nM for rat brain). Exhibits selectively for PKCα (IC50 = 2.3 nM) and βI (IC50 = 6.2 nM).
MilliporeSigma™ Calbiochem™ Cathepsin Inhibitor III
The Cathepsin Inhibitor III controls the biological activity of Cathepsin. This small molecule/inhibitor is primarily used for Protease Inhibitors applications.
MilliporeSigma™ Calbiochem™ Brk Inhibitor, Cpd 4f
A cell permeable, highly potent, and very selective inhibitor of breast tumor kinase (Brk; IC50 = 3.15 nM). Displays anti-proliferative activity against multiple breast cancer cell lines.
MilliporeSigma™ Calbiochem™ SB 202190
SB 202190, CAS 152121-30-7, is a potent, reversible, competitive inhibitor of p38. Inhibits p38 phosphorylation of myelin basic protein. Blocks the activity of p38β (K
MilliporeSigma™ Calbiochem™ Sphingosine Kinase Inhibitor
The Sphingosine Kinase Inhibitor, also referenced under CAS 1177741-83-1, controls the biological activity of Sphingosine Kinase. This small molecule/inhibitor is primarily used for Cell Signaling applications.
MilliporeSigma™ Calbiochem™ Protease Inhibitor Cocktail Set VIII
The Protease Inhibitor Cocktail Set VIII controls the activity of Protease. This small molecule/inhibitor is primarily used for Protease Inhibitors applications.
MilliporeSigma™ Calbiochem™ Ezrin Inhibitor, NSC668394
The Ezrin Inhibitor, NSC668394 controls the biological activity of Ezrin.
MilliporeSigma™ Calbiochem™ Bupropion Hydrochloride
Bupropion is a non-selective inhibitor of dopamine and noradrenalin transporters. Also an antagonist for neuronal nicotinic acetylcholine receptors (nAChrs).
MilliporeSigma™ Calbiochem™ Pepstatin A Methyl Ester
A cell-permeable methyl ester derivative of Pepstatin A that acts as a potent, non-competitive, transition-state analog inhibitor of γ-secretase.
MilliporeSigma™ Calbiochem™ SRT1720
SRT1720, CAS 925434-55-5, is a cell-permeable inhibitor of the mitochondrial SIRT3. Inhibition is AceCS2-competitive (Ki = 0.56μM; Km = 2.44μM), but NAD+-uncompetitive (Ki = 0.34μM; Km = 280μM).