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Materials that simulate clinical samples and are used with diagnostic glucose tests to monitor assay performance and ensure the accuracy of test results.
Hexokinase is responsible for catalyzing the first step of glycolysis. It results in the formation of glucose-6-phosphate and ADP from glucose and ATP. Glucose-6-phosphate dehydrogenase is a crucial enzyme in the pentose phosphate pathway. It is responsible for the conversion of glucose-6-phosphate and NADP (nicotinamide adenine dinucleotide phosphate) to 6-phosphogluconolactone and NADPH.
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Hexokinases phosphorylate glucose to produce glucose-6-phosphate the first step in most glucose metabolism pathways This gene encodes hexokinase 2 the predominant form found in skeletal muscle It localizes to the outer membrane of mitochondria Expression of this gene is insulin-responsive and studies in rat suggest that it is involved in the increased rate of glycolysis seen in rapidly growing cancer cells
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