Substrates
Enzo Life Sciences NG-Hydroxy-L-arginine . monoacetate (25mg). CAS: 53598-01-9
Intermediate in NO biosynthesis. Intermediate in the biosynthesis of nitric oxide from L-arginine by nitric oxide synthases (NOS). Inhibitor of arginases. Alternative name: L-HOArg . AcOH. Formula: C6H14N4O3 . CH3COOH. MW: 190.2 . 60.1. Purity: ≥98% (HPLC). Appearance: White to off-white solid. Solubility: Soluble in water (50mg/ml). Long Term Storage: +4°C.
Enzo Life Sciences Boc-Leu-Arg-Arg-AMC (5mg)
A substrate for the Kex2 endopeptidase from S. cerevisiae. This peptide is also a substrate for kallikrein 5 (KLK5), and a candidate substrate for the investigation of proteasome subunit function. Alternative name: Boc-LRR-AMC. Purity: ≥97% (HPLC). Solubility: Soluble in water (50mg/ml). Long Term Storage: -20°C.
Enzo Life Sciences Histone H3 dimethyl lysine-4 peptide (0.5mg)
Residues 1-21 from the N-terminal tail of human histone H3, dimethylated on the side-chain (ε-amino function) of Lys4. Useful as a substrate for histone lysine demethylases, for example LSD1. Purity: ≥95% (HPLC). Formulation: Lyophilized. Solubility: Soluble in Water. Long Term Storage: -20°C.
Enzo Life Sciences OMNIMMP RED fluorogenic substrate (100µg)
Highly-quenched, ultra-bright fluorogenic substrate for most MMPs. 6’-TAMRA fluorescence is thoroughly quenched by the TQ3 group until cleavage by MMPs separates the two moieties. The OMNIMMP RED substrate offers key advantages over other MMP substrates. Purity: ≥90% (HPLC). Solubility: Soluble in DMSO (50mM). Long Term Storage: -20°C.
Enzo Life Sciences CSH103 substrate (500µg). CAS: 135546-44-0
This sequence, ADAQHATPPKKKRKVED, is SV40 L Tag (118-138) with Ser to Ala120 and Ala123 substitutions to increase specificity. Substrate is specific for p34cdc2 (CDK1) and is a poor substrate for CKI, II, PKA, GSK3, PKC, CaMKII, and phosphorylase b kinase. Can be used in cell lysates using TCA/phosphocellulose assay. Km=74 µM for active complex with cyclin B. Long Term Storage: -20°C.
Selleck Chemical LLC D-Luciferin
D-Luciferin is a popular bioluminescent substrate of luciferase in the presence of ATP used in luciferase-based bioluminescence imaging and cell-based high-throughput screening applications In an immunocompetent mouse model of ovarian cancer the use of D-luciferin substrate and firefly luciferase preserves tumour-host immune interactions since bioluminescent imaging is a more sensitive indication of tumour growth than weight gain
Medchemexpress LLC Ac-DEVD-AMC | 169332-61-0 | MFCD00671411 | 99.2% | 675.64 | 10 MG
Ac-DEVD-AMC is a fluorescent substrate for caspase-3/caspase-7. When treated with cell lysate, it releases amino-4-methylcoumarin (AMC) for fluorescence detection.
- Fluorescent substrate for caspase-3/caspase-7
- Releases amino-4-methylcoumarin (AMC) for fluorescence detection
- Excitation wavelength of 380 nm
- Emission wavelength of 460 nm
Enzo Life Sciences Ac-YVAD-AFC (5mg)
Fluorogenic substrate for caspase-1 and -4. Alternative name: Caspase 1 substrate (fluorogenic), Caspase 4 substrate (fluorogenic). Formula: C33H36F3N5O10. MW: 719.7. Purity: ≥97% (HPLC). Solubility: Soluble in DMSO. Long Term Storage: -20°C.
Enzo Life Sciences 7-Ethoxyresorufin (10mg). CAS: 5725-91-7
Fluorimetric substrate for cytochrome P450 IA1. Inhibits vasorelaxant responses to acetylcholine. Alternative name: 7-ER. Purity: ≥98%. Solubility: Soluble in DMSO (5mg/ml) or 100% ethanol (5mg/ml). Long Term Storage: Ambient.
Medchemexpress LLC MBP MAPK Substrate | 138028-00-9 | 99.6% | 967.09 | 10 MG
MBP MAPK Substrate is utilized as an exogenous substrate for MAPK.
- Sequence: Ala-Pro-Arg-Thr-Pro-Gly-Gly-Arg-Arg
- Solubility: H2O
- Powder storage: -80°C for 2 years, -20°C for 1 year (sealed storage, away from moisture)
- Solvent storage: -80°C for 6 months, -20°C for 1 month (sealed storage, away from moisture)
Revvity Health Sciences Inc LANCE Ultra poly Glu Ala Tyr Ulight Peptide Substrate, 10 nmoles
LANCE Ultra poly Glu Ala Tyr Ulight Peptide Substrate, 10 nmoles
Medchemexpress LLC EGFR/HER2-IN-9 | 1637253-79-2 | C25H25ClFN5O4 | 5 MG
EGFR/HER2-IN-9 (Compound 1) is an EGFR and HER2 inhibitor for research use only.
- Inhibits EGFR with an IC50 of 3.2 nM
- Inhibits EGFR T790M with an IC50 of 8.3 nM
- Inhibits HER2 with an IC50 of 14 nM
Enzo Life Sciences Ac-YVAD-pNA (5mg). CAS: 149231-66-3
Sequence is a modification of pro-interleukin-1β Asp-116 cleavage site for caspase-1. Similar to Ac-YVAD-AMC but cleavage is monitored colorimetrically at 405nm. Alternative name: Caspase-1 substrate (chromogenic). Formula: C29H36N6O10. MW: 628.6. Purity: ≥97% (HPLC). Formulation: Lyophilized. Solubility: Soluble in DMSO. Dilute with buffer pH 7.5. Long Term Storage: -20°C.
Enzo Life Sciences Furin convertase substrate (fluorogenic) (5mg). CAS: 136132-77-9
Fluorogenic substrate for furin/SPC1/PACE/PCSK3 and other subtilisin/kexin-like proprotein convertases such as Kex2, SPC2/PC2/PCSK2, SPC3/PCSK1, PACE4/SPC4/PCSK6, SPC5/PC4/PCSK4, SPC6/PC5/PC6/PCSK5, and SPC7/LPC/PC7/PC8/PCSK7. Can be used on live cells. Ex: 360-380 nm, Em: 440-460 nm. Alternative name: Boc-RVRR-AMC, Boc-Arg-Val-Arg-Arg-AMC. Formula: C38H62N14O8. MW: 843.0. Purity: ≥95% (HPLC; TLC). Appearance: White to off-white powder. Solubility: Soluble in water (10mg/ml) or DMSO. Long Term Storage: -20°C. Handling: Protect from light.