Substrates
Cayman Chemical PGE2 Substrate 250uL
A PDGFR and FGFR inhibitor (IC50s 5.35 4.6 28 28 and 78 nM for PDGFRa PDGFRB FGFR1 -2 and -3 respectively) selective for these kinases over FGFR4 (IC50 >1000 nM) but also inhibits c-Kit VEGFR2 VEGFR1 and IGF-1R (IC50s 67 33 36 and 75 nM respectively) as well as EGFR BTK Cdk4/cyclin D3 and MET (IC50s 128 198 214 and 396 nM respectively) inhibits the proliferation of MG-63 U2OS MNNG/HOS and Saos-2 cells (IC50s 0.84 0.76 1.36 and 0.72 UM respectively) inhibits the migration and invasion of U87MG and LN-229 cells at 0.3 and 0.5 UM decreases tumor volume and increases survival in a U87MG orthotopic mouse xenograft model 30 mg/kg
Ubpbio K48-linked tetra-Ubiquitin (human), enzymatically synthesized
Ub chains are formed by conjugating the C-terminal glycine residue of Ub onto any of seven internal lysine residues or the amino group of the previous Ub. Ub chains are classified by the lysine residue used to link Ubs; different Ub chain topologies can result in different signals. For instance, Ub chains linked through lysine 6, 11, 27, 29, 33 and 48 are capable of targeting proteins for proteasomal degradation; in contrast, Ub chains linked through lysine 63 or the N-terminal amino group (linear Ub chains) often play important nonproteolytic functions including regulation of kinase activation and protein translation. All Ub chain products are produced by using of human wild type Ub reacting with specific E2s.
Avanti Polar Lipids PIP2 POWDER
L- alpha -Phosphatidylinositol-4,5-bisphosphate (Brain, Porcine-Triammonium Salt). 383907-42-4
Ubpbio K63-linked tetra-Ubiquitin (human), enzymatically synthesized
Ub chains are formed by conjugating the C-terminal glycine residue of Ub onto any of seven internal lysine residues or the amino group of the previous Ub. Ub chains are classified by the lysine residue used to link Ubs; different Ub chain topologies can result in different signals. For instance, Ub chains linked through lysine 6, 11, 27, 29, 33 and 48 are capable of targeting proteins for proteasomal degradation; in contrast, Ub chains linked through lysine 63 or the N-terminal amino group (linear Ub chains) often play important nonproteolytic functions including regulation of kinase activation and protein translation. All Ub chain products are produced by using of human wild type Ub reacting with specific E2s.
Ubpbio K48-linked di-Ubiquitin (human), enzymatically synthesized
Ub chains are formed by conjugating the C-terminal glycine residue of Ub onto any of seven internal lysine residues or the amino group of the previous Ub. Ub chains are classified by the lysine residue used to link Ubs; different Ub chain topologies can result in different signals. For instance, Ub chains linked through lysine 6, 11, 27, 29, 33 and 48 are capable of targeting proteins for proteasomal degradation; in contrast, Ub chains linked through lysine 63 or the N-terminal amino group (linear Ub chains) often play important nonproteolytic functions including regulation of kinase activation and protein translation. All Ub chain products are produced by using of human wild type Ub reacting with specific E2s.
Research Products International Corp D-Luciferin Free Acid 500 MG
Used with firefly luciferase in bioluminescence for the determination of ATP.
Seracare Life Sciences Inc STABLEDAB HRP SUBSTRATE KIT
StableDAB remains active and does not precipitate over a 2 week period at use dilution; at ambient temperature it remains stable for 1 week. At 2-8C it remains stable for 2 weeks. Diaminobenzidine (DAB)is the most commonly used substrate for the histochemical detection of peroxidase. It reacts with HRP to produce an insoluble brown precipitate and can be used in staining tissues and on membranes. The main disadvantage of DAB is that it must be used immediatley to avoid reaction with the enzyme. KPL's StableDAB overcomes this disadvantage and can remain ready-to-use for 2 weeks after preparation. Kit includes StableDAB Peroxidase Substrate and Buffer Concentrate.Smooth muscle actin in skin tissue, using streptavidin peroxidase stained with StableDAB, Contrast BLUE counterstain.
Sigma Aldrich Fine Chemicals Biosciences 2-Nitrophenyl Beta-D-Glucopyranoside | 2816-24-2 | MFCD00065048 | 250mg
2-Nitrophenyl Beta-D-Glucopyranoside | Mol Wt: 301.25 | 2816-24-2 | MFCD00065048 | 250mg
Bioworld IPTG (Isopropyl-B-D-ThioGalactopyranoside) Solution, 100mM, 10 mL
Isopropyl-β-D-Thiogalactopyranoside, an inducer of β-galactosidase is used to promote the expression of proteins in cells controlled by the lac operator system. Supplied as 1ml or 10x1ml of 100mM ready-to-use solution to be used with X-gal for blue white colony screening. Techncial Information:Biotechnology Grade.Ready-to-use solution Sterile filtered (0.22μM)Dioxane freeApplication: Petriplates: Use 40 μl per Petriplates (9 cm diameter). LB agar: Use 1μl/mL of liquid LB agar medium just before pouring (~50°C).Liquid culture: Use 1μl/mL of liquid culture medium.Sold as 1mL or 10 x 1mL.
Bioworld 4-Methylumbelliferyl-á-D-Glucopyranoside, 1 g
4-Methylumbelliferyl-α-D-glucopyranoside[4-Methylumbelliferyl-α-D-Glucoside]C16H18O8MW 338.3Fluorescent substrate for -α-D-Glucosidase.Purity: >98%. 4-Methylumbelliferone <50ppm.Soluble in 2% acetone/water 1:1.CAS 17833-43-1This product is sold for laboratory research use only.
Bioworld ABTS, Diammonium Salt, 10 g
ABTS, Diammonium Salt Also known as 2,2'-Azino-bis(3-ethylbenzthiazoline-6-sulfonic acid). Technical Information:Ultra Pure GradePurity: >98.0%Em (225nm, H2O): >48.150Solubility (H2O): 5%Store: Frozen
Abcam 1,2-Dioleoyl-3-(pyren-1-yl) decanoyl-rac-glycerol, 1MG
MW 975.5 Da. Fluorescent triglyceride analog useful for measuring cholesteryl ester transfer and protein-mediated triacylglycerol transport between plasma lipoproteins. Popular substrate for detections of lipoprotein lipase and hepatic triacylglycerol lipases.
The product is subject to the following: Abcam Restricted Use Statement