Isotopically Labeled Compounds
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Filtered Search Results
Cayman Chemical 9-OxoDE-d3 50ug
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An internal standard for the quantification of 9-OxoODE by GC- or LC-MS
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Revvity Health Sciences Inc Deoxy-D-glucose, 2-[1,2-3H(N)]-, 250µCi (9.25MBq)
Deoxy-D-glucose, 2-[1,2-3H(N)]-, 250µCi (9.25MBq)
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Medchemexpress LLC Nonanoic acid-d2 | 62689-94-5 | 10 MG
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Nonanoic acid-d2 is a deuterium-labeled, naturally occurring saturated fatty acid with nine carbon atoms. It has been shown to reduce bacterial translocation, enhance antibacterial activity, and increase the secretion of porcine β-defensins 1 and 2.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
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Medchemexpress LLC Methionine-d3 | 284665-18-5 | 99.2% | 152.23 | 25 MG
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Methionine-d3 is the deuterium-labeled Methionine. Methionine is an effective chemoprotective agent that can also inhibit neuronal activity through GABAA receptor activation.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Stable heavy isotopes are incorporated into drug molecules as tracers for quantitation during drug development.
- Deuteration has potential to affect pharmacokinetic and metabolic profiles of drugs.
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Medchemexpress LLC Pregnanetriol-d4 | 2687960-83-2 | 99.84% | C21H32D4O3 | 1 MG
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Pregnanetriol-d4 is a deuterium-labeled form of Pregnanetriol, suitable for research applications. It can serve as a tracer and an internal standard for quantitative analysis using techniques such as NMR, GC-MS, or LC-MS. Deuterium substitution, which involves incorporating stable heavy isotopes of hydrogen, carbon, and other elements into drug molecules, has attracted attention due to its potential to influence the pharmacokinetic and metabolic profiles of drugs.
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- Available as a white to off-white solid
- Intended for research use only
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Medchemexpress LLC Indomethacin-d4 | 87377-08-0 | MFCD06658917 | 99.8% | C19H12D4ClNO4 | 1 MG
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Indomethacin-d4 is a deuterium-labeled derivative of Indomethacin, a potent, blood-brain permeable, and nonselective inhibitor of COX1 and COX2. This compound also disrupts autophagic flux by disturbing the normal functioning of lysosomes. It is suitable for use as a tracer or an internal standard in quantitative analysis methods such as NMR, GC-MS, or LC-MS.
- Deuterium-labeled Indomethacin
- Potent, blood-brain permeable, and nonselective COX1 and COX2 inhibitor
- Disrupts autophagic flux
- Suitable as a tracer in drug development
- Can be used as an internal standard for quantitative analysis
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Cambridge Isotope Laboratories Bensulide (isopropoxy-D14 98%) 100 ug/mL in acetonitrile 1 2 mL
Bensulide (isopropoxy-D14 98%) 100 ug/mL in acetonitrile 1 2 mL
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Cambridge Isotope Laboratories L-Tyrosine (3 5-13C2 99% 2 3 3 2 6-D5 98% 15N 98%) 0 1 g
L-Tyrosine (3 5-13C2 99% 2 3 3 2 6-D5 98% 15N 98%) 0 1 g
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Medchemexpress LLC Cefepime-d8 sulfate | 131857-33-5 | 99.2% | C19H18D8N6O9S3 | 1 MG
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Cefepime-d8 sulfate is a deuterium-labeled form of Cefepime sulfate, intended for research purposes. It is useful for understanding drug pharmacokinetics and metabolic profiles.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
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Medchemexpress LLC Clomipramine-d6 hydrochloride | 1189882-28-7 | 1 MG
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Clomipramine-d6 hydrochloride is a deuterium labeled form of Clomipramine hydrochloride, a potent 5-HT reuptake blocker with an IC50 value of 1.5 nM. It is a tricyclic antidepressant used in research for depression and obsessive compulsive disorder (OCD). Deuteration can influence the pharmacokinetic and metabolic profiles of drugs.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Deuteration has potential to affect pharmacokinetic and metabolic profiles of drugs.
- Suitable for research of depression and obsessive compulsive disorder (OCD).
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Medchemexpress LLC N-(5-Sulfamoyl-1,3,4-thiadiazol-2-yl)acetamide-2,2,2-d3 | 1189904-01-5 | 99.9% | 5 MG
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Acetazolamide-d3 is a deuterium-labeled version of Acetazolamide, a potent carbonic anhydrase (CA) IX inhibitor with an IC50 of 30 nM for hCA IX. It exhibits diuretic, antihypertensive, and anti-gonococcal activities. This product is intended for research use only and has not been fully validated for medical applications.
- Deuterium labeled Acetazolamide
- Potent carbonic anhydrase (CA) IX inhibitor
- IC50 of 30 nM for hCA IX
- Exhibits diuretic activity
- Exhibits antihypertensive activity
- Exhibits anti-gonococcal activity
- Suitable for research applications
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Medchemexpress LLC Maprotiline-d3 hydrochloride | 1329496-63-0 | 98.8% | 5 MG
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Maprotiline-d3 (hydrochloride) is a deuterium labeled version of Maprotiline (hydrochloride) and is intended for research use only.
- Can be utilized as a tracer.
- Functions as an internal standard for quantitative analysis using techniques such as NMR, GC-MS, or LC-MS.
- Deuterium substitution can influence the pharmacokinetic and metabolic profiles of drugs.
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Medchemexpress LLC Estriol-d2 | 53866-32-3 | 98.5% | 500 UG
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Estriol-d2 is a deuterium-labeled version of Estriol. It acts as an antagonist of the G-protein coupled estrogen receptor in estrogen receptor-negative breast cancer cells. Intended for research use only, this compound serves as a tracer and internal standard for quantitative analysis using techniques such as NMR, GC-MS, or LC-MS. Deuteration in drug molecules is utilized for quantitation during development and can impact pharmacokinetic and metabolic profiles.
- Functions as an antagonist of the G-protein coupled estrogen receptor
- Used as a tracer in research
- Serves as an internal standard for quantitative analysis
- Molecular formula: C18H22D2O3
- Molecular weight: 290.39
- Available in powder form
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Medchemexpress LLC Dibenzothiophene-d8 | 33262-29-2 | 5 MG
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Dibenzothiophene-d8 is a deuterium-labeled version of Dibenzothiophene, a noncompetitive CYP1A inhibitor that interacts with the AHR pathway. It is primarily used to study the mechanism of developmental toxicity. Dibenzothiophene-d8 can serve as a tracer or internal standard for quantitative analysis.
- Deuterium-labeled compound
- Functions as a tracer
- Serves as an internal standard for quantitative analysis via NMR, GC-MS, or LC-MS
- Useful for studying developmental toxicity mechanisms
- Deuteration potentially affects pharmacokinetic and metabolic profiles
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Medchemexpress LLC Azelaic acid-d14 | 119176-67-9 | 99.9% | 50 MG
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Azelaic acid-d14 is the deuterium labeled Azelaic acid, an organic compound produced by the ozonolysis of oleic acid and a component of various hair and skin conditioners. It is intended for research use only.
- Used as a tracer.
- Acts as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Deuterium labeling may impact pharmacokinetic and metabolic profiles of drugs.
- Incorporates stable heavy isotopes into drug molecules for quantitation during drug development.
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