Isotopically Labeled Compounds
Medchemexpress LLC Nemonoxacin-d3 | 99.9% | 374.45 | 1 MG
Nemonoxacin-d3 is a deuterated compound, chemically known as 3-Quinolinecarboxylic acid, 7-[(3S,5S)-3-amino-5-methyl-1-piperidinyl]-1-cyclopropyl-1,4-dihydro-8-methoxy-4-oxo-d3. This compound has a molecular weight of 374.45 and is supplied as a high-purity material, primarily intended for research applications.
- High purity of 99.9%
- Confirmed structure by 1H NMR and LCMS
- Isotopic enrichment of 99.76%
- Off-white to light yellow solid appearance
- Stable for extended periods when stored properly
Medchemexpress LLC Salbutamol-d3 | 1219798-60-3 | 98.68% | 1 MG
Salbutamol-d3 (Albuterol-d3) is a deuterium-labeled version of Salbutamol, an orally active, short-acting β2-adrenergic receptor agonist. It promotes tumorigenesis in gastric cancer cells through the β2-AR/ERK/EMT pathway and can relax bronchial smooth muscle, making it useful for studying bronchospasm induced by asthma and chronic obstructive pulmonary disease. Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules for use as tracers during drug development, and deuteration can affect the pharmacokinetic and metabolic profiles of drugs.
- Used as a tracer.
- Used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Medchemexpress LLC 2,4(1H,3H)-pyrimidinedione-5,6-d2 | 24897-52-7 | 99.9% | 114.10 | C4H2D2N2O2 | 10 MG
Uracil-d2 is the deuterium-labeled analogue of uracil, used as an isotopic standard and tracer in analytical and metabolic studies. It is a white to off-white solid with molecular formula C4H2D2N2O2 and CAS number 24897-52-7.
- Deuterium-labeled for mass spectrometry tracing and isotopic studies.
- High reported purity (≈99.9%).
- Suitable as an internal standard for quantitative assays.
- Supplied in small research quantities appropriate for analytical applications.
- Stable as a powder with recommended cold storage to preserve isotopic integrity.
Medchemexpress LLC Pyridostigmine-d6 bromide | 2375858-08-3 | 100.0% | 267.15 | C9H7D6BrN2O2 | 10 MG
Pyridostigmine-d6 (bromide) is the deuterium-labeled form of pyridostigmine used as a stable-isotope research standard and a reversible cholinesterase inhibitor for biochemical and neuronal signaling studies.
- Deuterium-labeled internal standard suitable for mass spectrometry and quantitative assays.
- High chemical purity (99.96%).
- Molecular weight 267.15; molecular formula C9H7D6BrN2O2.
- CAS number 2375858-08-3 for unambiguous identification.
- Available in small research pack sizes, including a 10 mg vial.
- Storage: store sealed at 4°C; in solvent store at -80°C (6 months) or -20°C (1 month).
Medchemexpress LLC p-Toluic acid-d3 | 19215-16-8 | >98.0% | 139.17 g/mol | C8H5D3O2 | 10 MG
p-Toluic acid-d3 (4-methylbenzoic acid-d3) is the deuterium-labeled form of p-toluic acid, intended for analytical and synthetic use. It is used as a tracer and internal standard for quantitative analysis by NMR, GC-MS, or LC-MS, and as an intermediate in organic synthesis.
- Used as an internal standard for NMR, GC-MS, and LC-MS quantitative analysis.
- Suitable as a synthetic intermediate for organic chemistry applications.
- Available in small-scale quantities for analytical use, e.g., 10 MG.
- Chemical purity min 98% with isotopic enrichment typically 98 atom % D.
Cambridge Isotope Laboratories L-METHIONINE (13C5, 99%; 15N, 99%), 0.05 G, 202468-47-1
L-METHIONINE (13C5, 99%; 15N, 99%), 0.05 G, 202468-47-1
Medchemexpress LLC Bexarotene-d4 | 2182068-00-2 | 98.5% | C24H24D4O2 | 1 MG
Bexarotene-d4 is a deuterium-labeled compound, serving as a selective retinoid X receptors (RXR) agonist. It is used as a tracer or an internal standard for quantitative analysis in various methods.
- Used for treating cutaneous T-cell lymphoma
- Suitable as a tracer for quantitative analysis
- Can be used as an internal standard for quantitative analysis
- Compatible with NMR, GC-MS, or LC-MS methods
Medchemexpress LLC Nizatidine-d3 | 1246833-99-7 | MFCD32641299 | 98.8% | 334.48 | C12H18D3N5O2S2 | 10 MG
Nizatidine-d3 is the deuterium-labeled form of nizatidine supplied as an isotope-labeled reference standard for research applications, including mass spectrometry, pharmacokinetic, and metabolic studies. It is intended for use as a labeled internal standard to support quantitative analytical workflows.
- Deuterium-labeled internal standard for mass spectrometry assays.
- High chemical purity: 98.8%.
- CAS number 1246833-99-7 for unambiguous identification.
- Available in small-mass packaged quantities suitable for analytical use.
- Useful for ADME, PK/PD, and quantitative analytical studies.
Medchemexpress LLC Citric acid-d4 | 147664-83-3 | MFCD00209702 | 99.3% | 196.15 | C6H4D4O7 | 10 MG
Citric acid-d4 is the deuterium-labeled form of citric acid supplied as a white to off-white solid. It serves as a stable-isotope reference standard for analytical workflows, including mass spectrometry, NMR, isotopic tracer experiments, and quantitative assays. Molecular formula C6H4D4O7; molecular weight 196.15; purity 99.31%.
- Deuterium labeled (d4) for isotope dilution and tracer studies.
- High purity for reliable quantitation.
- Solid form simplifies weighing and solution preparation.
- Available in small research-sized pack quantities.
- Stable when stored sealed away from moisture and light.
Medchemexpress LLC Palmitic acid-2-13C | 287100-87-2 | MFCD00083983 | 98.0% | 10 MG
Palmitic acid-13C is a stable isotope-labeled palmitic acid supplied for use as a tracer or internal standard in analytical and biochemical applications, including GC-MS and LC-MS workflows. It provides a defined isotopic label for metabolic tracing and quantification.
- Used as a tracer and internal standard in GC-MS and LC-MS analyses.
- Stable isotope labeled (13C) fatty acid for metabolic tracing.
- Purity 98.0% as provided.
- CAS number 287100-87-2 for unambiguous identification.
- Provided as a 10 MG package; additional sizes available.
Medchemexpress LLC L-ascorbic acid-d2 | 82977-10-4 | 99.9% | 178.14 | C6H6D2O6 | 10 MG
L-ascorbic acid-d2 is the deuterium-labeled form of L-ascorbic acid used as an analytical standard and tracer in biochemical and mass spectrometry applications. It is a white to off-white solid with molecular formula C6H6D2O6 and molecular weight 178.14 g/mol. Supplied in small mass pack sizes for analytical workflows.
- Deuterium-labeled compound for tracer and quantitative analyses.
- High chemical purity (99.9%) suitable for analytical use.
- White to off-white solid, easy to handle and weigh.
- Storable as powder at -20°C for long-term stability.
- Available in small pack sizes for calibration and method development.
Medchemexpress LLC Isoxsuprine-d6 (hydrochloride) | 2706004-35-3 | 99.9% | 500 UG
Isoxsuprine-d6 (hydrochloride) is the deuterium-labeled Isoxsuprine hydrochloride. Isoxsuprine hydrochloride is a beta-adrenergic receptor agonist with Kis of 13.65 μΜ and 3.48 μΜ for myometrial and placental beta-adrenergic receptors, respectively. It is also an NMDA receptor antagonist.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Medchemexpress LLC Entacapone-d10 | 1185241-19-3 | 98.6% | C14H5D10N3O5 | 1 MG
Entacapone-d10 is the deuterium-labeled version of Entacapone, a potent, reversible, peripherally acting, and orally active catechol-O-methyltransferase (COMT) inhibitor. It can be used as a tracer and as an internal standard for quantitative analysis.
- Inhibits COMT from rat brain, erythrocytes and liver with IC50 values of 10 nM, 20 nM, and 160 nM.
- Selective for COMT over other catecholamine metabolizing enzymes.
- Can be used for the research of Parkinson's disease.
- Serves as an inhibitor of FTO demethylation with an IC50 of 3.5 μM.
- Can be used for the research of metabolic disorders.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.