Isotopically Labeled Compounds
Medchemexpress LLC Nonadecane | 629-92-5 | 100 MG
Nonadecane is a herbicide used for the control of weeds in Dendrobium orchids. This product is provided as a colorless to off-white solid.
- Purity: 98.0%
- Molecular weight: 268.52
- Chemical formula: C19H40
- Appearance: Solid
- Color: Colorless to off-white
- Shipping: Room temperature in continental US; may vary elsewhere
- Powder storage: -20°C for 3 years, 4°C for 2 years
- In solvent storage: -80°C for 6 months, -20°C for 1 month
- Solubility in ethanol: 20 mg/mL (74.48 mM)
Medchemexpress LLC Oleic acid-d2 (9-cis-octadecenoic acid-d2) | 5711-29-5 | 99.6% | 10 MG
Oleic acid-d2 is the deuterium-labeled form of oleic acid (9-cis-octadecenoic acid) provided as a neat liquid for use as a tracer and internal standard in quantitative NMR, GC-MS, and LC-MS analyses. It is reported to modulate Na+/K+ ATPase activity and is supplied with high isotopic and analytical purity for research applications.
- Deuterium-labeled internal standard for quantitative mass spectrometry and NMR.
- High analytical purity (99.6%).
- Molecular formula C18H32D2O2 and molecular weight 284.47.
- Available in research-scale quantities, including 10 mg vials.
- Colorless to light yellow liquid; density approximately 0.896 g/cm3.
Medchemexpress LLC Betaine-d3 chloride | 1219349-47-9 | 98.6% | 156.63 g/mol | C5H9D3ClNO2 | 10 MG
Betaine-d3 chloride is the deuterium-labeled form of betaine chloride intended for use as an isotopic tracer and internal standard in quantitative NMR, GC-MS, and LC-MS analyses for research applications.
- Deuterium-labeled internal standard for quantitative NMR, GC-MS, and LC-MS.
- Reported purity 98.6%.
- Molecular weight 156.63 g/mol.
- Molecular formula C5H9D3ClNO2.
- Available in a 10 mg package suitable for analytical workflows.
- For research use only; not for human or clinical use.
Medchemexpress LLC Nizatidine-d3 | 1246833-99-7 | MFCD32641299 | 98.8% | 334.48 | C12H18D3N5O2S2 | 10 MG
Nizatidine-d3 is the deuterium-labeled form of nizatidine supplied as an isotope-labeled reference standard for research applications, including mass spectrometry, pharmacokinetic, and metabolic studies. It is intended for use as a labeled internal standard to support quantitative analytical workflows.
- Deuterium-labeled internal standard for mass spectrometry assays.
- High chemical purity: 98.8%.
- CAS number 1246833-99-7 for unambiguous identification.
- Available in small-mass packaged quantities suitable for analytical use.
- Useful for ADME, PK/PD, and quantitative analytical studies.
Medchemexpress LLC Picolinic-3,4,5,6-d4 acid | 284487-61-2 | MFCD00145121 | 100.0% | 127.14 | C6HD4NO2 | 10 MG
Picolinic acid-d4 is the deuterium-labeled isotopologue of picolinic acid used as a stable-isotope reference standard and tracer in analytical workflows. It is supplied with high isotopic enrichment for use as an internal standard in quantitative methods and is intended for research use only.
- Deuterium-labeled internal standard for quantitative analysis.
- High isotopic enrichment (99.99%) for accurate tracing.
- Suitable for NMR, GC-MS, and LC-MS applications.
- Available in small laboratory-scale quantities for standards preparation.
- Provided with product quality data for analytical use.
Medchemexpress LLC Phenylmethan-d2-ol | 21175-64-4 | MFCD00084124 | 99.0% | 110.15 | C7H6D2O | 50 MG
Phenylmethan-d2-ol is the alpha,alpha-dideuterated form of benzyl alcohol used as a stable isotope reagent and internal standard in analytical and synthetic chemistry. It is supplied as a high-purity, isotopically enriched compound suitable for mass spectrometry, isotopic labeling, and mechanistic studies.
- Deuterium label at alpha positions
- High isotopic enrichment (>99.0%)
- Molecular formula C7H6D2O, molecular weight 110.15
- Small-quantity formats suitable for analytical workflows
- Used as a mass spectrometry internal standard and isotopic tracer
- Accompanied by product datasheet for purity and handling information
Medchemexpress LLC D18 | 2230218-36-5 | 98.8% | C21H28N6 | 1 MG
D18 is an immune modulator and acts as a TLR7/8 dual agonist. It increases PD-L1 expression through epigenetic regulation, sensitizing tumors to PD-1/PD-L1 blockade. This substance is also an ADC cytotoxin used for the synthesis of ADC HE-S2 (HY-144497) and exhibits strong immune activation and anti-tumor activity, commonly used in cancer research.
- Acts as a TLR7/8 dual agonist
- Increases PD-L1 expression through epigenetic regulation
- Sensitizes tumors to PD-1/PD-L1 blockade
- Utilized as an ADC cytotoxin for ADC HE-S2 synthesis
- Exhibits strong immune activation and anti-tumor activity
- Used in cancer research, including colon cancer
Medchemexpress LLC Vildagliptin-d3 | 1217546-82-1 | C17H22D3N3O2 | 500 UG
Vildagliptin-d3 is a deuterium labeled Vildagliptin. It is a potent, stable, selective dipeptidyl peptidase IV (DPP-IV) inhibitor with an IC50 of 3.5 nM in human Caco-2 cells. It possesses excellent oral bioavailability and potent antihyperglycemic activity. Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
![Medchemexpress LLC 1-Naphthalenesulfonyl chloride, 5-[di(methyl-d3)amino]- | 1276379-68-0 | 98.0% | 1 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000410136-logo.png-250.jpg){kind=logo}
Medchemexpress LLC 1-Naphthalenesulfonyl chloride, 5-[di(methyl-d3)amino]- | 1276379-68-0 | 98.0% | 1 MG
Dansyl chloride-d6 is the deuterium labeled form of Dansyl chloride, a reagent known for producing stable blue or blue-green fluorescent sulfonamide adducts. It reacts with aliphatic and aromatic amines containing primary amino groups and is widely utilized for modified amino acids, protein sequencing, and amino acid analysis. This compound serves as a valuable tracer and an internal standard for quantitative analysis using techniques such as NMR, GC-MS, or LC-MS.
- Can be used as a tracer
- Functions as an internal standard for quantitative analysis
- Applicable in NMR, GC-MS, or LC-MS
- Deuterium-labeled compound
Medchemexpress LLC Acesulfame-d4 potassium | 1623054-53-4 | 1 MG
Acesulfame-d4 potassium is the deuterium labeled Acesulfame (potassium) (HY-D0195). Acesulfame potassium is an artificial sweetener that affects cognitive functions, potentially by altering neuro-metabolic functions in mice.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Medchemexpress LLC Veratrole-d2 | 203645-56-1 | 99.7% | 50 MG
Veratrole-d2 is a deuterium-labeled form of Veratrole (1,2-Dimethoxybenzene), a compound naturally found in plants that attracts pollinators. Its release exhibits a circadian rhythm, playing an important role in plant reproduction, species differentiation, and interactions with pollinators. This compound can also be demethylated by cytochrome P-450 in *Streptomyces setonii*. Deuterated compounds like Veratrole-d2 are utilized as tracers for quantification during drug development due to their potential to influence the pharmacokinetic and metabolic profiles of drugs.
- Deuterium-labeled version of Veratrole
- Key compound in plant reproduction and interactions with pollinators
- Can be demethylated by cytochrome P-450
- Used as a tracer for quantification in drug development
- Potential to affect pharmacokinetic and metabolic profiles of drugs
Medchemexpress LLC Terconazole-d4 | 1398065-50-3 | 5 MG
Terconazole-d4 is the deuterium labeled Terconazole. Terconazole is a broad-spectrum antifungal medication used for the treatment of vaginal yeast infection.
- Deuterium labeled compound
- Broad-spectrum antifungal
- Treats vaginal yeast infection
Cambridge Isotope Laboratories Methanol-d4 (d, 99.8%), 811-98-3, MFCD00044637, 10 g
Chemical Formula: CD3OD, MW: 36.07, 99.8%, Synonyms: Methyl hydride; Marsh gas; Natural gas.
Medchemexpress LLC Mequinol-d4 (4-methoxyphenol-d4) | 126840-02-6 | 128.16 | C7H4D4O2 | 10 MG
Mequinol-d4 is the d4 isotopologue of 4-methoxyphenol supplied as a 10 mg powder for research use. It is intended as a stable isotope reference standard and analytical reagent for tracer studies, method development, and mass spectrometry applications. For research use only; not for human or clinical use.
- Deuterium-labeled reference standard for analytical applications.
- Suitable as an internal standard for mass spectrometry and tracer studies.
- Supplied as a 10 mg powder for laboratory use.
- Molecular weight 128.16; chemical formula C7H4D4O2.
- Recommended storage: powder -20°C; in solvent -80°C (6 months) or -20°C (1 month).