Isotopically Labeled Compounds
Medchemexpress LLC Pyridoxal-d3 hydroch 1mg | 1173023-49-8 | 1MG
Pyridoxal-d3 (hydrochloride) is the deuterium labeled Pyridoxal hydrochloride[1
Medchemexpress LLC Mequinol-d4 | 126840-02-6 | 98.9% | 128.16 | 5 MG
Mequinol-d4 is a laboratory chemical primarily used for research. It is presented as a solid and is stable under recommended storage conditions. This substance is not classified as hazardous and is intended for experienced personnel in appropriately equipped facilities.
- Used as a laboratory chemical
- Not classified as a hazardous substance
- Stable under recommended storage conditions
- Available as a solid
- Recommended storage for powder: -20°C for 3 years
- Recommended storage in solvent: -80°C for 6 months, -20°C for 1 month
- High purity (98.9%)
Medchemexpress LLC L-Hydroxyproline-d3 | 1356016-86-8 | 99.9% | 134.15 | 5 MG
L-Hydroxyproline-d3 is the deuterium labeled L-Hydroxyproline. L-Hydroxyproline, one of the hydroxyproline (Hyp) isomers, is a useful chiral building block in the production of many pharmaceuticals.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Deuterium substitution has the potential to affect the pharmacokinetic and metabolic profiles of drugs.
Medchemexpress LLC Nifedipine-d6 | 1188266-14-9 | >98% | 5 MG
Nifedipine-d6 (BAY-a-1040-d6) is deuterium labeled nifedipine, which is a potent calcium channel blocker. It is intended for research use only.
- Deuterium labeled nifedipine
- Potent calcium channel blocker
- Intended for research use only
Medchemexpress LLC Estrone-d2-1 | 56588-58-0 | 99.8% | 1 MG
Estrone-d2-1 is a deuterium-labeled form of Estrone (E1), a natural estrogenic hormone produced in various tissues like adipose tissue. It is formed through the aromatization of androstenedione in fat cells. This product is for research use only.
- Stable heavy isotopes incorporated into drug molecules for use as tracers.
- Deuteration can impact pharmacokinetic and metabolic profiles of drugs.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- High purity: 99.75%.
Medchemexpress LLC Adenosine-d13 | 58-61-7 | 96.6% | 5 MG
Adenosine-d13 is a deuterium-labeled form of Adenosine, an endogenous autacoid crucial for various cellular processes. It interacts with G protein-coupled receptors (A1, A2A, A2B, and A3) and plays a role in neuronal activity, vascular function, platelet aggregation, and blood cell regulation.
- Used as a tracer
- Can serve as an internal standard for quantitative analysis
- Suitable for analysis techniques such as NMR, GC-MS, or LC-MS
Medchemexpress LLC Nicotinamide-d4 | 347841-88-7 | 99.9% | 1 MG
Nicotinamide-d4 is the deuterium labeled Nicotinamide, a form of vitamin B3 essential for cell physiology through NAD+ redox homeostasis. It serves as a substrate for enzymes catalyzing non-redox reactions and is an inhibitor of SIRT1. This product is intended for research use only.
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
Medchemexpress LLC Adenine-13C | 86967-48-8 | 99.1% | 5 MG
Adenine-13C is the 13C labeled Adenine. Adenine (6-Aminopurine), a purine, is one of the four nucleobases in the nucleic acid of DNA. It acts as a chemical component of DNA and RNA and plays an important role in biochemistry involved in cellular respiration, the form of both ATP and the cofactors (NAD and FAD), and protein synthesis.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Medchemexpress LLC Octopamine-d4 hydrochloride | 1219803-62-9 | 98.0% | 1 MG
Octopamine-d4 hydrochloride is a deuterium-labeled form of Octopamine hydrochloride. It acts as a neurohormone, neuromodulator, and neurotransmitter in invertebrates, stimulating alpha2-adrenoceptors. It has been observed to increase glycogenolysis, glycolysis, oxygen uptake, gluconeogenesis, and portal perfusion pressure.
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
Medchemexpress LLC Desvenlafaxine-d6 | 1062605-69-9 | 1 MG
Desvenlafaxine-d6 is deuterium labeled Desvenlafaxine, an orally active and BBB penetrated 5-HT and norepinephrine reuptake inhibitor. It shows weak binding affinity at the human dopamine (DA) transporter. Deuterated compounds like Desvenlafaxine-d6 are used as tracers for quantitation during drug development due to their potential to affect pharmacokinetic and metabolic profiles.
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
Medchemexpress LLC L-Carnitine-d9 | 126827-79-0 | ≥99.0% | 1 MG
L-Carnitine-d9 is a deuterium-labeled L-Carnitine, an endogenous molecule involved in fatty acid metabolism. Biosynthesized in the human body using L-lysine and L-methionine, it transports long-chain fatty acyl-CoAs into mitochondria for degradation through β-oxidation. It can also improve metabolic imbalances in various inborn errors of metabolism.
- Deuterium-labeled L-Carnitine for tracing during drug development.
- Participates in fatty acid metabolism.
- Transports long-chain fatty acyl-CoAs into mitochondria.
- May improve metabolic imbalances in inborn errors of metabolism.
Medchemexpress LLC 2'-Deoxyuridine-13C,15N2 | 369656-76-8 | 98.1% | 1 MG
2'-Deoxyuridine-13C,15N2 is the 13C and 15N labeled 2'-Deoxyuridine, a compound that can increase chromosome breakage and decrease thymidylate synthetase activity. It is also known as a precursor in the synthesis of Edoxudine.
- Can increase chromosome breakage.
- Results in decreased thymidylate synthetase activity.
- Precursor in the synthesis of Edoxudine.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.