Isotopically Labeled Compounds
Medchemexpress LLC Vortioxetine-d8 hydrobromide | 960203-27-4 | C18H15D8BrN2S | 1 MG
Vortioxetine-d8 hydrobromide, also known as Lu AA 21004-d8 hydrobromide, is a deuterated form of Vortioxetine. Vortioxetine acts as an antagonist of 5-HT3A and 5-HT7 receptors, and an inhibitor of the 5-hydroxytryptamine transporter (SERT). It also functions as a 5-HT1A agonist and a partial 5-HT1B agonist.
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- Targets 5-HT1A receptor
- Targets 5-HT1B receptor
- Targets 5-HT3A receptor
- Targets 5-HT7 receptor
Medchemexpress LLC IDH1 inhibitor 7-d2 | 2135309-51-0 | C₂₂H₂₂D₂F₃N₃O | 1 MG
IDH1 Inhibitor 7-d2 is a deuterium labeled IDH1 Inhibitor 7, which functions as an IDH1 inhibitor with an IC₅₀ of less than 100 nM. This compound incorporates stable heavy isotopes, which can be used as tracers during drug development for quantitation and may influence the pharmacokinetic and metabolic profiles of drugs.
- IDH1 inhibitor with an IC₅₀ of less than 100 nM
- Incorporates stable heavy isotopes for potential use as tracers
- Deuteration may affect pharmacokinetic and metabolic profiles of drugs
Medchemexpress LLC L-Glutamine-13C5,15N2 | 285978-14-5 | 153.09 | 5 MG
L-Glutamine-13C5,15N2 is a 13C- and 15N-labeled form of L-Glutamine, a non-essential amino acid crucial for many metabolic processes. This compound provides a source of carbons for oxidation in various cells and appears as a white to off-white solid. It is intended for research use only.
- Used as a tracer
- Used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
Medchemexpress LLC L-Cystine-15N2 | 952407-61-3 | 242.29 | 5 MG
L-Cystine-15N2 is the 15N-labeled L-Cystine. L-Cystine is an amino acid and intracellular thiol, which plays a critical role in the regulation of cellular processes. It can be used as a tracer and as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Used as a tracer.
- Used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Stable under recommended storage conditions.
- For research use only.
Medchemexpress LLC Tridecane-d28 | 121578-12-9 | MFCD00145015 | 98.1% | 212.53 g/mol | C13D28 | 10 MG
Tridecane-d28 is the deuterium-labeled form of tridecane used as an isotopic reference standard for analytical and research applications. It is fully deuterated (C13D28), with high isotopic enrichment and is supplied in small pack sizes suitable for analytical use.
- fully deuterated alkane, useful as an internal standard for mass spectrometry
- reported purity about 98.05%
- molecular weight 212.53 g/mol and formula C13D28
- available in small research pack sizes for analytical workflows
- volatility similar to tridecane, suitable for GC applications
Medchemexpress LLC 1-Methylxanthine-d3 | 1216430-61-3 | 169.16 | 1 MG
1-Methylxanthine-d3 is a deuterated labeled form of 1-Methylxanthine, a caffeine derivative and an essential human urinary metabolite of caffeine and theophylline. It has been shown to enhance the radiosensitivity of tumor cells. This compound is intended for research use only and can serve as a tracer or an internal standard for quantitative analysis methods like NMR, GC-MS, or LC-MS.
- Used as a tracer
- Used as an internal standard for quantitative analysis
- Enhances the radiosensitivity of tumor cells
- Stable heavy isotopes incorporated for drug development quantitation
Medchemexpress LLC Trehalose 6,6'-dimycolate (cord factor) | 61512-20-7 | MFCD18643296 | 97.0% | 2053.4 g/mol | C130H250O15 | 1 MG
Trehalose 6,6′-dimycolate is a mycobacterial cell-wall glycolipid used as a research reagent to model Mycobacterium tuberculosis-induced inflammation and granuloma formation. It modulates innate and adaptive immune responses and is applied in both in vitro and in vivo immunology studies.
- Mimics mycobacterial cord factor activity.
- Induces granuloma formation and inflammatory signaling.
- Modulates macrophage killing and antigen presentation.
- Suitable for in vitro and in vivo immunology research.
- Provided as small-quantity, high-purity material (97.0%).
Medchemexpress LLC p-Fluorophenol-d6 | 1219804-93-9 | 98.5% | 117.13 | C6D5FO | 100mg
p-Fluorophenol-d6 is the deuterium labeled p-Fluorophenol[1]
Medchemexpress LLC Mequinol-d4 | 126840-02-6 | 98.9% | 128.16 | 50 MG
Mequinol-d4 is a chemical substance primarily intended for laboratory research and the manufacture of other substances. This product is for research use only and should be handled by suitably qualified experienced scientists in appropriately equipped and authorized facilities. It presents as a white to off-white solid.
- Intended for laboratory chemical applications
- Stable under recommended storage conditions
- Can be stored as powder at -20°C for 3 years
- Can be stored in solvent at -80°C for 6 months
- Appears as a white to off-white solid
Medchemexpress LLC Lamotrigine-d3 | 1132746-94-1 | 1 MG
Lamotrigine-d3 is the deuterium labeled Lamotrigine. Lamotrigine (BW430C) is a potent and orally active anticonvulsant or antiepileptic agent. It selectively blocks voltage-gated Na+ channels, stabilizing presynaptic neuronal membranes and inhibiting glutamate release. Lamotrigine can be used for the research of epilepsy, focal seizure, among others. It is intended for research use only. This compound can be used as a tracer and as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS. Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
Cambridge Isotope Laboratories D-Glucose (1-13C 99% 6-13C 97%) 1 g
D-Glucose (1-13C 99% 6-13C 97%) 1 g
Cayman Chemical DeoxycholIc ACDd4 MaxSpec
A quantitative analytical standard guaranteed to meet MaxSpec identity, purity, stability, and concentration specifications
Medchemexpress LLC (2S,4R)-4-hydroxypyrrolidine-2-carboxylic-2,4,5,5-d4 acid | 2734920-51-3 | 99.9% | 135.15 | C5H5D4NO3 | 1 MG
Deuterium-labeled L-hydroxyproline used as a chiral building block and as an analytical internal standard for quantitative methods. Supplied as a white to off-white solid with high isotopic enrichment and high chemical purity, the compound is intended for research and analytical applications where labeled internal standards are required.
- Deuterium labeled at positions 2, 4, 5, and 5.
- High purity (99.9% HPLC) and high isotopic enrichment.
- Suitable as tracer and internal standard for NMR, GC-MS, and LC-MS quantitative analysis.
- White to off-white solid; stable when stored as powder at -20 °C or in solution at -80 °C.
- Available in small mg quantities (1 MG, 5 MG, 10 MG) for analytical use.
Cambridge Isotope Laboratories L-GLUTAMINE (13C5, 97-99%; D5, 97-99%; 15N2, 97-99%), 0.25 G
L-GLUTAMINE (13C5, 97-99%; D5, 97-99%; 15N2, 97-99%), 0.25 G
Cambridge Isotope Laboratories ETHYL BROMOACETATE (1,2-13C2, 99%), 0.5 G, 61898-49-5
ETHYL BROMOACETATE (1,2-13C2, 99%), 0.5 G, 61898-49-5