Isotopically Labeled Compounds
Medchemexpress LLC 1,6-anhydro-β-D-glucopyranose-d7 | 2483832-05-7 | 99.9% | 169.18 g/mol | C6H3D7O5 | 5 MG
Levoglucosan-d7 is the deuterium-labeled isotopologue of levoglucosan intended for research and analytical applications, commonly used as an internal standard in mass spectrometry assays.
- deuterium-labeled levoglucosan (stable isotope standard)
- intended for research and analytical applications, such as internal standard use in mass spectrometry
- cas number 2483832-05-7
- molecular formula C6H3D7O5
- molecular weight 169.18 g/mol
- purity 99.9%
- package size 5 mg
- storage: powder -20 °C (3 years), 4 °C (2 years); in solvent -80 °C (6 months), -20 °C (1 month)
Medchemexpress LLC Choline-d13 chloride | 352438-97-2 | 99.90% | 1 MG
Choline-d13 (chloride) is a deuterium-labeled form of Choline chloride, which is an organic compound and a quaternary ammonium salt. It serves as an acyl group acceptor and a choline acetyltransferase substrate. Choline chloride is also utilized as an important feed additive, particularly for chickens, where it promotes growth.
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- Stable heavy isotopes have been incorporated into drug molecules for quantitation during drug development
- Deuteration has potential to affect pharmacokinetic and metabolic profiles of drugs
Medchemexpress LLC 2-Piperidinecarboxamide, N-(2,6-dimethylphenyl)-1-propyl-d7 | 1392208-04-6 | 99.6% | 1 MG
(Rac)-Ropivacaine-d7 is a stable isotope-labeled compound, identified as 2-Piperidinecarboxamide, N-(2,6-dimethylphenyl)-1-propyl-d7. It appears as a white to off-white solid with an isotopic enrichment of 99.11%. This product is intended for research use only and should be handled by qualified personnel in appropriately equipped facilities.
- High purity of 99.6% (HPLC)
- Stable under recommended storage conditions
- Ideal for laboratory chemical applications and substance manufacturing
- For research use only
Medchemexpress LLC 2-Oxazolidinone, 5-[(3,5-dimethylphenoxy-2,4,6-d3)methyl]- | 1192812-66-0 | 98.0% | 5 MG
Metaxalone-d3 is a deuterium-labeled derivative of Metaxalone, an FDA-approved muscle relaxant. It primarily acts on the central nervous system by inhibiting polysynaptic reflex arcs. It also inhibits MAO-A, offering anti-inflammatory and antioxidant effects. Stable heavy isotopes have been incorporated into drug molecules for tracing and can influence drug pharmacokinetics and metabolic profiles.
- Deuterium labeled Metaxalone
- FDA-approved muscle relaxant
- Inhibits polysynaptic reflex arcs
- Inhibits MAO-A, providing anti-inflammatory and antioxidant effects
- Isotopic enrichment of 99.10%
Medchemexpress LLC ((2-(6-Amino-9H-purin-9-yl)ethoxy)methyl)phosphonic acid-d4 | 1190021-70-5 | 98.7% | 2.5 MG
Adefovir-d4 is the deuterium labeled Adefovir, an adenosine monophosphate analog antiviral agent. After intracellular conversion to Adefovir diphosphate, it inhibits HBV DNA polymerase, with an IC50 of 0.7 μM against HBV in the HepG2.2.15 cell line. It exhibits good antiviral activity against several viruses, including HBV and herpesviruses.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Incorporation of stable heavy isotopes into drug molecules can affect pharmacokinetic and metabolic profiles.
Medchemexpress LLC Uric acid-15N2 | 62948-75-8 | 99.95% | 1 MG
Uric acid-15N2 is the 15N labeled Uric acid. Uric acid is a scavenger of oxygen radicals and a crucial antioxidant that helps maintain blood pressure stability and antioxidant stress. It can remove reactive oxygen species (ROS) such as singlet oxygen and peroxynitrite, thereby inhibiting lipid peroxidation. This compound is intended for research use only.
- Can be used as a tracer.
- Internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Helps maintain blood pressure stability.
- Removes reactive oxygen species (ROS).
- Inhibits lipid peroxidation.
Cayman Chemical Enobosarm-d4 1mg
An internal standard for the quantification of enobosarm by GC- or LC-MS
Medchemexpress LLC Ethambutol-d4 | 1129526-19-7 | 98.1% | 1 MG
Ethambutol-d4 is a deuterium-labeled version of Ethambutol, a bacteriostatic antimycobacterial agent. It functions by inhibiting arabinosyl transferases, thereby obstructing the formation of bacterial cell walls. This compound can be utilized as a tracer and as an internal standard for quantitative analysis in various methods.
- Deuterium-labeled ethambutol
- Bacteriostatic antimycobacterial agent
- Inhibits arabinosyl transferases
- Obstructs bacterial cell wall formation
- Suitable for use as a tracer
- Internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
Medchemexpress LLC Spermine-d8 tetrahydrochloride | 1173022-85-9 | 95% | 5 MG
Spermine-d8 (tetrahydrochloride) is the deuterium labeled Spermine tetrahydrochloride, a polyamine nitric oxide donor found in mammalian tissues, plants, bacteria, ribosomes, and bacteriophage. It acts as a natural antioxidant and anti-inflammatory agent, and is known to inhibit certain bacterial cultures. It can reversibly inhibit DNA synthetic response and mixed lymphocyte response.
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules for quantitation during drug development
- Deuteration has gained attention due to its potential to affect the pharmacokinetic and metabolic profiles of drugs
Medchemexpress LLC Cmpf-d5 | 2749807-07-4 | 99.0% | 1 MG
CMPF-d5 is the deuterium labeled CMPF, which serves as a valuable tool for quantitative analysis using techniques such as NMR, GC-MS, or LC-MS. The strategic deuterium substitution in drug molecules has garnered attention due to its potential to significantly impact their pharmacokinetic and metabolic profiles, offering insights into drug development processes.
- Functions as a tracer or internal standard in quantitative analytical methods.
- Influences the pharmacokinetic and metabolic profiles of various drugs.
- Recommended storage for powder is -20°C for up to 3 years.
- Recommended storage for solutions is -80°C for 6 months or -20°C for 1 month.
- Requires careful handling, avoiding inhalation and contact with skin or eyes.
- Store in a tightly sealed container within a cool, well-ventilated environment.
Medchemexpress LLC Ranitidine-d6 hydrochloride | 1185238-09-8 | 97.0% | 1 MG
Ranitidine-d6 hydrochloride is the deuterium labeled Ranitidine hydrochloride (HY-B0281A). Ranitidine hydrochloride is a potent, selective and orally active histamine H2-receptor antagonist that inhibits gastric secretion. It antagonizes Histamine (HY-B1204)-induced increases of the guinea-pig isolated rat atrium and Histamine-induced relaxations of the rat isolated uterine horn, with pA2 values of 7.2 and 6.95, respectively. Ranitidine hydrochloride also inhibits breast tumor development and spread in mice.
- This compound can be used as a tracer.
- This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Target: H2 receptor.
Medchemexpress LLC L-citrulline-d7 | 2483831-24-7 | 99.8% | 182.23 | C6H6D7N3O3 | 10 MG
L-Citrulline-d7 is the deuterium-labeled isotopologue of L-citrulline supplied as a solid stable-isotope standard for research and analytical applications. It is intended for use as an internal standard or tracer in quantitative mass spectrometry and metabolic studies, and is provided with documented purity and storage recommendations.
- Deuterium-labeled internal standard for mass spectrometry and tracer studies.
- Molecular formula C6H6D7N3O3 and molecular weight 182.23.
- High chemical purity (99.8%).
- Solid powder form with storage recommendations: powder -20°C (3 years) or 4°C (2 years).
- Supplied as a 10 mg aliquot suitable for analytical use.
Medchemexpress LLC DL-Xylose | 25990-60-7 | MFCD00198055 | 98.0% | 1 ML
DL-Xylose is an organic synthesis intermediate, appearing as a white to off-white solid. This compound is intended for research applications only.
- Organic synthesis intermediate
- For research use only
- Soluble in water and PBS
Medchemexpress LLC Cyclosporin A-d4 | 59865-13-3 | 99.6% | 5 MG
Cyclosporin A-d4 is the deuterium labeled Cyclosporin A. Cyclosporin A (Cyclosporine A) is an immunosuppressant that binds to cyclophilin and inhibits the phosphatase activity of calcineurin with an IC50 of 5 nM. Cyclosporin A also inhibits CD11a/CD18.
- Used as a tracer
- Used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- Stable heavy isotopes incorporated into drug molecules
- Deuteration can affect pharmacokinetic and metabolic profiles of drugs