Choose the brand aligned with your industry so we can best serve your needs.
For researchers, scientists, and technical professionals: Your one-stop shop for the complete range of laboratory, production, and safety products and services.
Chemical compounds designed to clean and protect glass and quartz components within mass spectrometer instruments; products may be water- or hydrocarbon-soluble.
Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
(E)-AG 556 is a small-molecule, selective inhibitor of the epidermal growth factor receptor (EGFR) used in preclinical research to probe EGFR-mediated signaling and inflammatory responses. It inhibits EGFR kinase activity and has been reported to reduce LPS-induced TNF-α production. The compound is supplied as a high-purity powder and is also available as a ready-to-use 10 mM stock solution in 1 mL vials for convenient dosing in cellular and biochemical assays.
Selective EGFR inhibitor for signaling studies.
Reported to block LPS-induced TNF-α production in cell assays.
High purity suitable for biochemical and cell-based assays.
Available as powder and as a 10 mM stock solution for immediate use.
Molecular formula C20H20N2O3 and molecular weight 336.39 g/mol.
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
(E)-AG 556 is a small-molecule epidermal growth factor receptor (EGFR) inhibitor that also blocks LPS-induced TNF-α production. Supplied as a light yellow to yellow solid with high purity, it is used in biochemical and cell-based assays to investigate EGFR signaling and inflammation-related pathways.
Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
PMX-53 is a synthetic peptidic antagonist of the complement C5a receptor (CD88) used in research to probe complement-mediated inflammation. It is orally active and inhibits C5a-induced neutrophil responses with a reported IC50 of ≈20 nM. The compound is supplied as a solid; molecular formula C47H65N11O7; molecular weight 896.09 g·mol⁻1; recommended storage at -20°C (in solvent: -80°C for long-term).
Potent C5aR antagonist with low-nanomolar activity.
Active in both in vitro and in vivo models.
Peptidic structure suitable for mechanistic studies of complement signaling.
Stable solid form with defined storage conditions.
Available in small research pack sizes for experimental flexibility.
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
PMX 205 Trifluoroacetate is a cyclic hexapeptide antagonist targeting the complement C5a receptor (C5aR CD88) It is designed to competitively inhibit C5a binding to its receptor thereby modulating complement-mediated inflammatory pathways PMX 205 Trifluoroacetate exerts its biological activity primarily through competitive antagonism at C5aR reducing downstream inflammatory cellular responses In animal models PMX 205 Trifluoroacetate demonstrates anti-inflammatory effects Based on these pharmacological properties PMX 205 Trifluoroacetate holds research potential in the study of neuroinflammation Alzheimer s disease and chemically induced colitis
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More