Human SHP2 is supplied as a recombinant biotinylated protein in a 0.1 mg format for studies of phosphatase signaling and RAS pathway regulation. Applications include SHP2 phosphatase activity assays, Ras-Raf-MAPK pathway studies, Jak-Stat pathway studies, PI3 kinase pathway studies. Technical specifications are included below.- Quantity - 0.1 mg- Gene - PTPN11 / SHP2- Mutation / Variant - Wild-type- Organism - Human- Tag - N-terminal 6XHis and AviTag- Expression System - E. coli- Purity - greater than 80% by Coomassie staining- UniProt ID - Q06124- Amino Acid Range - 1-593- Activity - Specific activity greater than or equal to 100 pmol/min/ug by PNPP assay- Buffer - 20 mM Tris-HCl, pH 7.5, 100 mM NaCl, 5 mM 2-mercaptoethanol, 0.04% Tween 20, 20% Glycerol- Storage - -80 C- Biotinylated - Yes, N-terminusThis product is for research use only.