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A variety of media, supplemental media components, and reagents suitable for cell culture operations and processes. Products include fully prepared media as well as antibiotics, growth factors, contamination detection and removal reagents, cell dissociation reagents, and more.
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TFPI protein encoded by the TFPI gene is an important Kunitz-type serine protease inhibitor that regulates TF-dependent pathways in coagulation It inhibits factor X and VIIa-TF proteases preventing excessive clot formation TFPI Protein Human (HEK293 His) is the recombinant human-derived TFPI protein expressed by HEK293 with C-6 His labeled tag
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G-CSF a pivotal cytokine regulates hematopoiesis by controlling the production differentiation and function of granulocytes and monocytes-macrophages This monomeric protein specifically promotes granulocyte development playing a crucial role in immune system regulation and blood cell formation G-CSF Protein Human (HEK293 Fc) is the recombinant human-derived G-CSF protein expressed by HEK293 with N-hFc labeled tag
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TLR4 is a transmembrane receptor that recognizes PAMPs and DAMPs and cooperates with LY96 for LPS detection TLR4 activates MYD88-dependent and independent signaling pathways and participates in TIRAP TRAF6 and CD14-mediated endocytosis TLR4 Protein Human (sf9 His Solution) is the recombinant human-derived TLR4 protein expressed by Sf9 insect cells with C-His labeled tag
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FGF-9 is a member of mouse heparin-binding fibroblast growth factors located on the outside of cell membranes FGF-9 is a regulator of chondrogenesis and vascularization during bone development FGF-9 binds to fibroblast growth factor receptors (FGFRs) to activate downstream signaling pathways such as PI3K-AKT RAS-MAPK and protein kinase C (PKC) pathways FGF-9 regulates embryonic development cell proliferation cell differentiation and cell migration FGF-9 plays an important role in differentiation survival of neuronal cells and growth stimulation of glial tumors FGF-9 Protein Mouse (N-His) is a recombinant protein with a N-His label that consisting of 208 amino acids and is produced in E coli[1][2][3][4][5]
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HER4 Protein crucial in central nervous system development influences neural crest cell migration and axon guidance Additionally it participates in mammary gland differentiation inducing milk proteins and contributing to lactation HER4 Protein Rat (HEK293 His) is the recombinant rat-derived HER4 protein expressed by HEK293 with C-His labeled tag
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Recombinant rat fibroblast growth factor 23 supplied lyophilized; expressed in Escherichia coli and provided as a His-tagged fragment corresponding to amino acids Y25-V251. The protein is intended for in vitro biochemical assays, binding studies, and assay development and includes guidance for reconstitution and storage.
Recombinant rat FGF-23 (Y25-V251) with His tag.
Expressed in Escherichia coli and purified with low endotoxin.
Lyophilized from 10 mM Tris-HCl, 1 mM EDTA, 6% trehalose, pH 8.0.
Endotoxin level <1 EU/μg as determined by LAL method.
Approximate molecular weight 25-30 kDa by SDS-PAGE under reducing conditions.
Do not reconstitute below 100 μg/mL; after reconstitution stable at 4°C for 1 week or at -20°C longer with carrier protein.
Recommended to aliquot and store at -20°C or -80°C for extended storage.
Suitable for biochemical assays, binding studies, and assay development.
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TGFB1 proprotein is the precursor of latency-associated peptide (LAP) and active transforming growth factor Beta-1 (TGF- -1) chain which maintains TGF- -1 latency in the extracellular matrix TGFB1 binds non-covalently to TGF- -1 and interacts with environmental molecules (LTBP1 LRRC32/GARP LRRC33/NRROS) to regulate TGF- -1 activation TGF beta 1/TGFB1 Protein Canine (HEK293 His) is the recombinant canine-derived TGF beta 1/TGFB1 protein expressed by HEK293 with C-His labeled tag
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The CD4 protein is an integral membrane glycoprotein that plays a key role in immune responses In T cells it serves as a coreceptor for MHC class II molecules interacting with T cell receptors and initiating intracellular signaling pathways CD4 Protein Human (HEK293 Fc) is the recombinant human-derived CD4 protein expressed by HEK293 with C-hFc labeled tag
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LIFR Protein a signal-transducing molecule may share a common pathway with IL6ST Its soluble form acts as an inhibitor blocking LIF binding to receptors and reducing biological activity LIFR forms a heterodimer with IL6ST interacting with the CNTF and CNTFR complex indicating potential cross-talk and cooperative actions in cellular processes LIFR Protein Mouse (HEK293 His) is the recombinant mouse-derived LIFR protein expressed by HEK293 with C-His labeled tag
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VEGFR-1 protein is a tyrosine protein kinase receptor for VEGFA VEGFB and PGF and is critical for embryonic vasculature development angiogenesis cell survival migration macrophage function chemotaxis and cancer invasion It actively regulates postnatal retinal vitreous vascular degeneration and may act as a negative regulator of embryonic angiogenesis VEGFR-1 Protein Rat (HEK293 His) is the recombinant rat-derived VEGFR-1 protein expressed by HEK293 with C-His labeled tag
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ROR1 protein s minimal kinase activity in vitro suggests an improbable role as a tyrosine kinase in vivo It serves as a receptor for WNT5A activating NFkB signaling and potentially inhibiting WNT3A signaling Notably ROR1 plays a vital role in the inner ear facilitating innervation of auditory hair cells by spiral ganglion neurons ROR1 Protein Human (sf9 His) is the recombinant human-derived ROR1 protein expressed by Sf9 insect cells with C-His labeled tag
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ROR1 protein s minimal kinase activity in vitro suggests an improbable role as a tyrosine kinase in vivo It serves as a receptor for WNT5A activating NFkB signaling and potentially inhibiting WNT3A signaling Notably ROR1 plays a vital role in the inner ear facilitating innervation of auditory hair cells by spiral ganglion neurons ROR1 Protein Human (sf9 His) is the recombinant human-derived ROR1 protein expressed by Sf9 insect cells with C-His labeled tag
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The EGFR protein is a receptor tyrosine kinase that binds EGF family ligands and activates multiple signaling cascades Ligand binding induces receptor homo- or heterodimerization leading to autophosphorylation and recruitment of adapter proteins (such as GRB2) EGFR Protein Mouse (HEK293 His) is the recombinant mouse-derived EGFR protein expressed by HEK293 with C-10 His labeled tag
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The EGFR protein is a receptor tyrosine kinase that binds EGF family ligands and activates multiple signaling cascades Ligand binding induces receptor homo- or heterodimerization leading to autophosphorylation and recruitment of adapter proteins (such as GRB2) EGFR Protein Mouse (HEK293 Fc) is the recombinant mouse-derived EGFR protein expressed by HEK293 with C-hFc labeled tag
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