Cell Culture Media, Supplements, and Reagents
Medchemexpress LLC BiP inducer X | 101714-41-4 | 99.6% | 209.22 | 100 MG
BiP inducer X | 101714-41-4 | 99.6% | 209.22 | 100 MG
Medchemexpress LLC AS601245 | 345987-15-7 | 98.2% | 372.45 | 10 MG
AS601245 is an orally active, selective, ATP competitive JNK (c-Jun NH2-terminal protein kinase) inhibitor. It targets hJNK1, hJNK2, and hJNK3 isoforms and demonstrates significant selectivity over various other protein kinases. This compound exhibits neuroprotective properties and can be used in different in vitro and in vivo studies.
- Orally active, selective, ATP competitive JNK inhibitor
- Exhibits neuroprotective properties
- Shows selectivity over c-src, CDK2, c-Raf, and other Ser/Thr- and Tyr-protein kinases
- Synergistic effects with Clofibrate in CaCo-2 colon cancer cells
- Provides significant protection against delayed loss of hippocampal CA1 neurons in gerbil models of transient global ischemia
- Potent inhibitor of LPS-induced TNF-α release in mice
Miltenyi Biotec, Inc. Anti-LAP (TGF-b1)-PE, h, REA1214, 30 t
Identification and enumeration of LAP (TGF-β1)+ cells by flow cytometry.
This product is subject to the following: Miltenyi Biotec, Inc. Terms and Conditions of Sale For Products and Services
![Medchemexpress LLC 1,2-Ethanediamine, N1-[[3-[4,4-bis(ethoxymethyl)cyclohexyl]-1H-pyrazol-4-yl]methyl]-N1,N2-dimethyl | 1629013-22-4 | 99.4% | 366.54 g/mol | C20H38N4O2 | 5 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000262265.png-250.jpg)
Medchemexpress LLC 1,2-Ethanediamine, N1-[[3-[4,4-bis(ethoxymethyl)cyclohexyl]-1H-pyrazol-4-yl]methyl]-N1,N2-dimethyl | 1629013-22-4 | 99.4% | 366.54 g/mol | C20H38N4O2 | 5 MG
GSK3368715 (EPZ019997) is an orally active, reversible, S-adenosyl-L-methionine (SAM) uncompetitive type I protein arginine methyltransferase (PRMT) inhibitor used for biochemical and cell-based research into arginine methylation and oncology-related pathways.
- Orally active, reversible type I PRMT inhibitor.
- SAM uncompetitive mechanism of action.
- Potent activity with low-nanomolar activity against PRMT1 and PRMT8.
- High purity (99.4% by HPLC) for research applications.
- Molecular formula C20H38N4O2; molecular weight 366.54 g/mol.
- Intended for in vitro and cellular research use only.
- Supplied in small research pack sizes suitable for screening and assays.
![Medchemexpress LLC Urea, N-[2-chloro-7-[(3S,5S)-3,5-dimethyl-4-morpholinyl]pyrazolo[1,5-a]pyrimidin-6-yl]-... | 2682102-10-7 | 99.6% | 469.85 | C19H19ClF3N7O2 | 5 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000262908.png-250.jpg)
Medchemexpress LLC Urea, N-[2-chloro-7-[(3S,5S)-3,5-dimethyl-4-morpholinyl]pyrazolo[1,5-a]pyrimidin-6-yl]-... | 2682102-10-7 | 99.6% | 469.85 | C19H19ClF3N7O2 | 5 MG
MLT-231 is a potent, highly selective allosteric inhibitor of MALT1 intended for research use. It inhibits MALT1 enzymatic activity with IC50 ≈ 9 nM, prevents endogenous BCL10 cleavage (IC50 ≈ 160 nM), and has demonstrated antitumor activity in ABC-DLBCL xenograft models.
- Potent allosteric inhibition of MALT1 with low-nanomolar activity.
- Prevents BCL10 cleavage in cellular assays, supporting mechanism studies.
- Demonstrated antitumor activity in preclinical xenograft models.
- Available as solid and as DMSO solution for assay flexibility.
- High chemical purity for reproducible experimental results.
- Recommended storage conditions support long-term stability.
Medchemexpress LLC Butyryltimolol | 106351-79-5 | MFCD32898870 | 98.0% | 386.51 g·mol⁻¹ | C17H30N4O4S | 50 MG
Butyryltimolol is a β-adrenergic blocker and a lipophilic ester prodrug of timolol that improves corneal penetration and is used in ocular delivery research. Reported properties include molecular formula C17H30N4O4S, molecular weight ≈386.51 g·mol⁻¹, and typical purity ~98.0%.
- Improves corneal penetration of timolol.
- Acts as a β-adrenergic blocker and prodrug of timolol.
- Lipophilic ester structure enhances ocular delivery.
- Supplied as a research-grade material with high reported purity.
- Suitable for ocular pharmacology and formulation studies.
Medchemexpress LLC Recombinant human FLT3 protein, HEK293 hFc fusion | 100 UG
Recombinant human FLT3 extracellular domain produced in HEK293 cells and fused to a human Fc tag. Supplied lyophilized, the protein is intended for ligand-binding assays, ELISA, and receptor-ligand interaction studies; it includes storage and reconstitution recommendations and low endotoxin for sensitive assays.
- Expression system: HEK293 cells.
- Tag: human Fc fusion.
- Formulation: lyophilized from 20 mM PB, 150 mM NaCl, pH 7.4.
- Endotoxin level: <1 EU/μg.
- Apparent molecular weight: 100-145 kDa.
- Storage: store at -20°C; aliquot and freeze for long-term storage.
- Reconstitution guidance: do not reconstitute below 100 μg/mL.
- Biological activity: ED50 = 15.44 ng/mL in functional ELISA.
Medchemexpress LLC CD83 protein, rat (HEK293, His tag) | 10 UG
Recombinant rat CD83 protein produced in HEK293 mammalian cells with a C-terminal His tag. Intended for research applications to study CD83-mediated immune regulation, including biochemical assays and cell-based experiments. Supplied in a small-scale 10 μg format.
- Recombinant rat CD83 produced in HEK293 cells.
- C-terminal His tag to facilitate purification and detection.
- Mammalian expression preserves native post-translational modifications.
- Suitable for biochemical and cell-based immunology assays.
- Provided in a 10 μg format for small-scale experiments.
Medchemexpress LLC L-2-hydroxyglutaric acid (disodium) | 63512-50-5 | 99.1% | 192.08 g/mol | C5H6Na2O5 | 50 MG
L-2-hydroxyglutaric acid (disodium) is the disodium salt of L-2-hydroxyglutaric acid supplied for research use. It acts as an epigenetic modifier and putative oncometabolite, with reported biochemical activity against histone demethylases and mitochondrial creatine kinase. Available as a solid powder or as a 10 mM aqueous solution for laboratory use.
- Epigenetic modifier that can inhibit histone demethylases.
- Reported to inhibit mitochondrial creatine kinase (Mi-CK) (Km 2.52 mM; Ki 11.13 mM).
- High purity suitable for biochemical and cellular studies.
- Available as solid and as a 10 mM solution for convenient use.
- Provided for research use only.
Medchemexpress LLC DDR1 protein, mouse (HEK293, His) | >95.0% | 100 UG
Recombinant mouse discoidin domain receptor 1 (DDR1) protein produced in HEK293 cells and supplied as a 0.22 μm filtered PBS solution with a C-terminal His tag. The protein is >95% pure by reducing SDS-PAGE, has an approximate molecular weight of 50-60 kDa, and is provided in a 100 μg format for research applications.
- Expressed in HEK293 for mammalian-like post-translational modifications.
- Supplied as a 0.22 μm filtered PBS solution ready for assays.
- C-terminal His tag facilitates purification and detection.
- High purity (>95%) suitable for biochemical and cell-based studies.
- Amino acid range corresponds to accession Q03146-2 (D20-T414) representing functional domains.
Medchemexpress LLC Interleukin-1 receptor type 1 (IL-1R1), rat, recombinant, His-tagged | >95.0% | 10 UG
Recombinant rat interleukin-1 receptor type 1, corresponding to the extracellular region (M1-K352), expressed in HEK293 cells and carrying a C-terminal His tag. The protein retains ligand-binding activity to IL-1 family cytokines and is supplied in small research sizes suitable for biochemical and binding studies.
- Rat extracellular region spanning residues M1-K352.
- Expressed in HEK293 mammalian cells for native glycosylation.
- C-terminal His tag for purification and detection.
- Retains binding to IL-1α, IL-1β, IL-1Ra, and IL-38 (Kd ~0.1-1 nM).
- Purity greater than 95% as determined by reducing SDS-PAGE.
- Available sizes: 2 μg, 10 μg, 50 μg, 100 μg.
Medchemexpress LLC Calhex 231 hydrochloride | 2387505-78-2 | MFCD18252543 | 99.8% | 443.41 g/mol | C25H28Cl2N2O | 50 MG
Calhex 231 hydrochloride is the hydrochloride salt of a small-molecule negative allosteric modulator of the calcium-sensing receptor (CaSR). It is supplied as a white to off-white solid with high reported purity for use in biochemical and cellular research.
- Negative allosteric modulator of the calcium-sensing receptor (CaSR).
- High reported purity (99.8%) suitable for research applications.
- White to off-white solid, easy to handle and store.
- Available in multiple package sizes and solution forms for flexible use.
- Used as a tool compound in studies of CaSR signaling and related disease models.
Medchemexpress LLC Calhex 231 hydrochloride | 2387505-78-2 | 99.8% | 443.41 g/mol | C25H28Cl2N2O | 10 MG
Calhex 231 hydrochloride is a research-grade small molecule that functions as a negative allosteric modulator of the calcium-sensing receptor (CaSR). It inhibits Ca2+-induced inositol phosphate accumulation (IC50 ≈ 0.39 μM) and is used in cellular studies related to traumatic hemorrhagic shock and diabetic cardiomyopathy.
- Negative allosteric modulator of CaSR
- Blocks Ca2+-induced inositol phosphate accumulation (IC50 ≈ 0.39 μM)
- High purity (≈99.8%) suitable for in vitro research
- White to off-white solid appearance
- Stable when stored sealed and protected from moisture; recommended -20°C for solid storage