Mirus Bio LLC
Mirus Bio provides nucleic acid delivery systems for molecular and cell biology applications, including chemical transfection reagents, electroporation products, and virus production and transduction products.
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Mirus Bio™ TransIT™-LT1 Transfection Reagent
High-efficiency plasmid DNA delivery in many mammalian cell types, including primary cells. The TransIT™-LT1 Transfection Reagent is broad spectrum, low toxicity, and serum compatible, and is suitable for both transient and stable transfection.
| Promoter | None (Promoterless) |
|---|---|
| Content And Storage | Store for up to one year at 4°C. |
| Product Type | Transfection Reagent |
| Transfection Technique | Chemical Transfection |
| For Use With (Application) | Gene expression, shRNA expression, viral production and promoter analysis |
| Sterility | Sterile |
| Cell Type | Established Cell Lines,Stem Cells,Primary Cells,Hard-to-Transfect Cells |
Mirus Bio™ TransIT-PRO™ Transfection Kit
Specifically developed for mammalian protein production in suspension CHO and 293 cells. The PRO Boost Reagent is optional and enhances expression in certain media formulations. Use of TransIT-PRO Transfection Kit eliminates the need for a culture medium change post-transfection.
| Promoter | None (Promoterless) |
|---|---|
| Content And Storage | -20°C |
| Format | Tube |
| Product Type | Transfection Reagent |
| Transfection Technique | Chemical Transfection |
| For Use With (Application) | Mammalian Protein production in suspension 293 and CHO derived cells, eliminates the need for a culture medium change post-transfection and is suitable for both transient and stable transfection |
| Sterility | Sterile |
| Cell Type | Mammalian |
Mirus Bio™ TransIT™-BrCa Transfection Reagent
Dedicated breast-cancer-cell-line-specific reagent. Delivers efficiently to many breast cancer cell types and maintains low cellular toxicity. Transfection with TransIT™-BrCa Reagent does not require medium changes and can be performed in serum-containing medium.
| Promoter | None (Promoterless) |
|---|---|
| Format | Tube |
| Product Type | Transfection Reagent |
| Transfection Technique | Chemical Transfection |
| For Use With (Application) | Achieve high expression levels in breast cancer cell types including MCF-7, MDA-MB-231, MDA-MB-453, MDA-MB-468 and T47D, transient and stable transfections for gene expression, shRNA expression and promoter analyses |
| Sterility | Sterile |
| Cell Type | Cancer Cells |
Mirus Bio VirusGEN AAV Transfection Kit with RevIT AAV Enhancer
Paired with TransIT VirusGEN, the RevIT AAV Enhancer delivers higher titers for recombinant adeno-associated virus production
| Promoter | None (Promoterless) |
|---|---|
| Format | Tube |
| Product Type | AAV Transfection Kit with Enhancer |
| Transfection Technique | Chemical Transfection |
| Sterility | Sterile |
| Cell Type | 293-derived Cells |
Mirus Bio™ Ingenio™ Electroporation Solution
Proprietary Ingenio™ Electroporation Solution facilitates efficient and reliable delivery of nucleic acids to eukaryotic cells resistant to chemical transfection.
| Content And Storage | 4°C |
|---|---|
| Product Type | Electroporation Solution |
| For Use With (Equipment) | All electroporation device |
| Pulse Form | Exponential Decay Wave |
| For Use With (Application) | Electroporation |
| Sterility | Sterile |
Mirus Bio™ MiraCLEAN™ Endotoxin Removal Kit
Uses rapid phase extraction to remove bacterial endotoxins from nucleic acids for both in vivo and in vitro applications. The proprietary pink-colored EndoGO extraction reagent helps the user to visualize the interface between phases, facilitating phase separation and increasing nucleic acid recovery.
| Content And Storage | 4°C |
|---|---|
| Format | Kit |
| Product Type | Endotoxin Removal Kit |
| Isolation Technology | Organic Extraction |
| For Use With (Application) | Removes bacterial endotoxins from Nucleic Acids for both in vivo and in-vitro applications |
Mirus Bio™ TransIT-TKO™ siRNA Transfection Reagent
Enables high efficiency siRNA delivery and knockdown of target gene expression in many cell types, including primary cells. siRNA and DNA co-transfection is feasible with TransIT-TKO. Transfections do not require medium changes and can be performed in serum-containing medium.
| Promoter | None (Promoterless) |
|---|---|
| Format | Tube |
| Product Type | Transfection Reagent |
| Transfection Technique | Chemical Transfection |
| Concentration | 1.37 mg/mL |
| For Use With (Application) | Transfect small interfering RNA for knock out of target gene expression, optimal gene silencing in a large percentage of cells |
| Sterility | Sterile |
| Cell Type | Mammalian |
Mirus Bio™ TransIT™-Oligo Transfection Reagent
TransIT™-Oligo Transfection Reagent provides efficient transfection of a wide range of oligonucleotides and oligoribonucleotides into a variety of cell types. Transfections do not require media changes and can be performed in serum-containing media.
| Promoter | None (Promoterless) |
|---|---|
| Format | Tube |
| Product Type | Transfection Reagent |
| Transfection Technique | Chemical Transfection |
| For Use With (Application) | Provides efficient transfection of a wide range of Oligonucleotides and Oligoribonucleotides into a variety of cell types |
| Sterility | Sterile |
| Cell Type | Mammalian |
Mirus Bio™ TransIT™-293 Transfection Reagent
TransIT™-293 Transfection Reagent designed for high-efficiency, low-toxicity DNA transfection in HEK293 cells.
| Promoter | None (Promoterless) |
|---|---|
| Content And Storage | Store for up to one year at 4°C (do not freeze). |
| Format | Tube |
| Product Type | Transfection Reagent |
| Transfection Technique | Chemical Transfection |
| Concentration | 1.41 mg/mL |
| For Use With (Application) | High efficiency, low-toxicity DNA transfection in HEK293 cells |
| Sterility | Sterile |
| Cell Type | 293-derived Cells |
Mirus Bio™ TransIT™-Keratinocyte Transfection Reagent
TransIT™-Keratinocyte Transfection Reagent designed for highly efficient, low-toxicity DNA transfection in primary keratinocytes. Transfection does not required medium changes and can be carried out in serum-containing medium.
| Promoter | None (Promoterless) |
|---|---|
| Format | Tube |
| Product Type | Transfection Reagent |
| Transfection Technique | Chemical Transfection |
| Concentration | 1.37 mg/mL |
| For Use With (Application) | Highly efficient DNA or RNA transfection with minimal cellular toxicity, specifically for primary keratinocytes |
| Sterility | Sterile |
| Cell Type | Mammalian |
Mirus Bio™ TransIT-HeLaMONSTER™ Transfection Kit
High-efficiency, low-toxicity DNA transfection kit optimized for HeLa cells and associated cell lineages. This kit is suitable for both transient and stable transfection. Transfection does not require medium changes and can be performed in the presence of serum.
| Includes | Base and booster reagent |
|---|---|
| Promoter | None (Promoterless) |
| Content And Storage | Store at -20°C |
| Format | Tube |
| Product Type | Transfection Reagent |
| Transfection Technique | Chemical Transfection |
| Concentration | 1.33 mg/mL |
| For Use With (Application) | Gene expression and promoter analysis, optimized to provide superior transfection efficiency in HEK 293 cells without sacrificing cellular health |
| Sterility | Sterile |
| Cell Type | Tumor Cell Lines |
Mirus Bio™ flashBAC™ Baculovirus Expression System
flashBAC™ Baculovirus Expression System is a streamlined platform for the production of recombinant baculoviruses. Optimal for expression of most nuclear or cytoplasmic proteins.
| Promoter | None (Promoterless) |
|---|---|
| Content And Storage | Store flashBAC™ DNA at 4°C and control plasmid at -20°C |
| Format | Kit |
| Product Type | Transfection Reagent |
| Transfection Technique | Chemical Transfection |
| Sample Type | Baculovirus DNA,Plasmid DNA |
| For Use With (Application) | Transfection |
| Sterility | Sterile |
| Cell Type | Insect Cells |
Mirus Bio™ Label IT™ Nucleic Acid Labeling Kit, Fluorescein
Use the Label IT™ Nucleic Acid Labeling Kit, Fluorescein to efficiently and reproducibly attach marker molecules to DNA or RNA in a simple one-step reaction within minutes. Covalently attach labels without impacting hybridization performance.
| Includes | Label IT™ Reagent, Label IT™ reconstitution solution, 10X Labeling Buffer and solutions |
|---|---|
| Labeling Target | DNA (General), Oligos, RNA (General) |
| Format | Kit |
| Product Type | Label IT Fluorescein Labeling Kit |
| Final Product Type | DNA (Labeled), RNA (Labeled) |
| Label or Dye | FITC |
| For Use With (Application) | Efficient, direct, nonenzymatic labeling of DNA and RNA |
| Detection Method | Fluorescence |
Mirus Bio™ TransIT-VirusGEN™ Transfection Reagent
TransIT-VirusGEN™ Transfection Reagent is ideal for recombinant adeno-associated virus and lentivirus production.
| Promoter | None (Promoterless) |
|---|---|
| Content And Storage | Store at -10°C to -30°C |
| Description | Before each use, warm to room temperature and vortex gently. |
| Product Type | Transfection Reagent |
| Transfection Technique | Chemical Transfection |
| Shelf Life | 6 months from date of purchase, when properly stored and handled. |
| Sterility | Sterile |
| Cell Type | 293-derived Cells |
Mirus Bio pLIVE™ Vector
pLIVE In Vivo Expression and Reporter Vectors is a vector system designed to achieve long term expression in the livers of laboratory mice.