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Filtered Search Results
eMolecules 2480-23-1 | N-Methyl-L-valine | MFCD00037754 | 1g
Medchem Express | Methyldopate | 5mg | 722714461 | HY-B1696 | 6014-30-8 | MFCD00865839 | 239.271 | C12H17NO4
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Medchemexpress LLC Fmoc-Val-Cit-PAB-MMAE | 1350456-56-2 | 98.9% | 1345.67 | C73H104N10O14 | 50 MG
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Fmoc-Val-Cit-PAB-MMAE is an antibody-drug conjugate linker-payload conjugate that couples an Fmoc-protected Val-Cit-PAB cleavable linker to monomethyl auristatin E (MMAE) for use in antibody-drug conjugate research and development.
- Contains a cleavable Val-Cit-PAB linker that is susceptible to proteolytic release.
- Delivers monomethyl auristatin E (MMAE), a potent tubulin inhibitor.
- High reported purity suitable for research applications.
- Supplied as a white solid and available in multiple pack sizes.
- Provided with supporting documents such as SDS and certificate of analysis for safe handling and quality verification.
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Medchemexpress LLC Val-Cit-PAB-MMAF (sodium) | 863971-56-6 | 98.4% | 1159.39 | C58H91N10NaO13 | 50 MG
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Val-Cit-PAB-MMAF sodium is an antibody-drug conjugate (ADC) drug-linker conjugate that links the protease-cleavable Val-Cit-PAB peptide linker to the tubulin inhibitor monomethyl auristatin F (MMAF). Supplied as the sodium salt, it is intended for use as an ADC building block for research applications, supporting in vitro formulation and in vivo dosing studies.
- Protease-cleavable Val-Cit-PAB linker enabling cathepsin B-triggered payload release.
- MMAF payload provides potent tubulin polymerization inhibition.
- High purity suitable for research applications (98.4%).
- Soluble in DMSO and formulatable for in vivo administration with appropriate vehicles.
- Available in multiple small milligram package sizes for ADC synthesis and evaluation.
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Medchemexpress LLC Bcn-PEG1-Val-Cit-PABC-OH | 95.0% | 670.80 g/mol | C34H50N6O8 | 5 MG
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BCN-PEG1-Val-Cit-PABC-OH is a BCN-functionalized, cleavable PEG-based antibody-drug conjugate (ADC) linker containing a Val-Cit dipeptide and a para-aminobenzyl carbamate self-immolative spacer. It is supplied as a powder for conjugation and click chemistry with azide-functionalized payloads.
- Cleavable Val-Cit dipeptide with PABC self-immolative spacer.
- Single-unit PEG (PEG1) provides solubility and spacing.
- BCN group enables strain-promoted azide-alkyne cycloaddition (SPAAC) conjugation.
- Supplied as powder, soluble in DMSO, store at -20°C.
- Purity typically 95.0% and molecular weight ~670.80 g/mol.
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Medchemexpress LLC Val-cit-PAB-OH | 159857-79-1 | 379.45 | C18H29N5O4 | 25 G
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Val-cit-PAB-OH is a cleavable, protease-sensitive antibody-drug conjugate (ADC) linker that couples cytotoxic payloads to antibodies through a valine-citrulline dipeptide and a para-aminobenzyl (PAB) self-immolative spacer. It is designed to remain stable in circulation and release payloads upon intracellular protease cleavage, supporting targeted delivery in ADC synthesis.
- Cleavable by intracellular proteases via valine-citrulline mechanism.
- Stable in systemic circulation, reducing premature payload release.
- Enables self-immolative payload release through a PAB spacer.
- Compatible with common conjugation chemistries for ADC construction.
- Available in gram-scale quantities for research and scale-up synthesis.
- Supplied with manufacturer storage guidance for long-term stability.
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Medchemexpress LLC Val-Ala-PAB-MMAE | 1912408-92-4 | 98.9% | 1,037.33 g/mol | C55H88N8O11 | 10 MG
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Val-Ala-PAB-MMAE is a drug-linker conjugate that couples the cleavable Val-Ala-PAB peptide linker to monomethyl auristatin E (MMAE), a potent tubulin inhibitor, and is supplied for antibody-drug conjugate research and development.
- Drug-linker conjugate of Val-Ala-PAB and MMAE.
- Purity 98.9%.
- Molecular weight 1,037.33 g/mol; formula C55H88N8O11.
- Supplied in multiple pack sizes, including 10 mg.
- Intended for research use in antibody-drug conjugate development.
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Medchemexpress LLC Mc-Val-Cit-PAB-Gefitinib (chloride) | 98.7% | 1038.00 g·mol-1 | C50H63Cl2FN10O9 | 1 MG
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Mc-Val-Cit-PAB-Gefitinib (chloride) is a drug-linker conjugate consisting of the EGFR inhibitor gefitinib coupled to an Mc-Val-Cit-PAB linker, supplied for research use only.
- Drug-linker conjugate of gefitinib and Mc-Val-Cit-PAB linker.
- White to off-white solid appearance.
- Molecular formula C50H63Cl2FN10O9.
- Molecular weight 1038.00 g·mol-1.
- Reported purity 98.7%.
- Intended for research use only; not for human or animal therapeutic use.
- Store at -20°C in a sealed container, away from moisture and light.
- Available in small milligram package sizes for laboratory research.
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Medchemexpress LLC Val-cit-pab-mmaf (sodium) | 98.4% | 1159.39 g/mol | C58H91N10NaO13 | 5 MG
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Val-Cit-PAB-MMAF sodium is a drug-linker conjugate for antibody-drug conjugate (ADC) research that links the protease-cleavable peptide Val-Cit-PAB to the cytotoxic payload monomethyl auristatin F (MMAF). It is supplied as the sodium salt and intended for research use.
- Protease-cleavable Val-Cit-PAB linker coupled to MMAF.
- Intended for ADC research and conjugation workflows.
- High purity suitable for research applications.
- Soluble in DMSO at high concentration; in vivo formulations achieve ≥5 mg/mL with solvent mixtures.
- Provided in small research pack sizes for preclinical experiments.
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Medchemexpress LLC Fmoc-val-cit-pab-duocarmycin | 99.4% | 1050.59 g·mol-1 | C58H60ClN7O10 | 5 MG
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Fmoc-Val-Cit-PAB-duocarmycin is a drug-linker conjugate intended for antibody-drug conjugate (ADC) synthesis. It couples a duocarmycin-based cytotoxic payload to an Fmoc-Val-Cit-PAB cleavable spacer, providing a reagent for linker-payload incorporation during ADC development.
- Cleavable val-cit-pab spacer for protease-triggered release.
- Duocarmycin-based cytotoxic payload for potent cell killing.
- High purity (99.4%) with characterized molecular weight.
- Supplied as a solid, white to yellow, easy-to-handle material.
- Storage: powder -20°C; in solvent -80°C for long-term stability.
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eMolecules 1394238-92-6 | Fmoc-Val-Ala-PAB-PNP | Combi-Blocks, Inc. | MFCD28557283 | 680.714 | C37H36N4O9 | 98.000 | CC(C)[C@H](NC(=O)OCC1c2ccccc2-c2ccccc12)C(=O)N[C@@H](C)C(=O)Nc1ccc(COC(=O)Oc2ccc(cc2)[N+]([O-])=O)cc1 | 250mg | 797031066
Fmoc-Val-Ala-PAB-PNP | Combi-Blocks, Inc. | 1394238-92-6 | MFCD28557283 | 680.714 | C37H36N4O9 | 98.000 | CC(C)[C@H](NC(=O)OCC1c2ccccc2-c2ccccc12)C(=O)N[C@@H](C)C(=O)Nc1ccc(COC(=O)Oc2ccc(cc2)[N+]([O-])=O)cc1 | 250mg | 797031066
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Medchemexpress LLC Fmoc-Gly3-Val-Cit-PAB | 2647914-09-6 | 95.0% | 772.85 g/mol | C39H48N8O9 | 5 MG
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Fmoc-Gly3-Val-Cit-PAB is a Fmoc-protected, cleavable peptide-based ADC linker used for the synthesis of antibody-drug conjugates (ADCs). It contains a Val-Cit cleavable dipeptide and a para-aminobenzyl (PAB) self-immolative spacer and is supplied at 95.0% purity.
- Cleavable Val-Cit peptide linker.
- Fmoc-protected for solid-phase synthesis compatibility.
- Contains para-aminobenzyl (PAB) self-immolative spacer.
- Molecular weight 772.85 g/mol.
- Molecular formula C39H48N8O9.
- Available in small-scale research quantities (e.g., 5 mg).
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STA Pharmaceutical Fmoc-N-methyl-L-norvaline | 50 g | CAS 252049-05-1 | MDL MFCD01861326
Fmoc-N-methyl-L-norvaline is a Amino Acid reagent (Subcategory: N-Me AA) sold by WuXi TIDES. Offered in 50 g. Store at 4 °C. SDS available for reference.
Specifications
- CAS: 252049-05-1
- MDL: MFCD01861326
- InChIKey: HKELUUGCKFRJQM-IBGZPJMESA-N
- Molecular Weight: 353.418
- Molecular Formula: C21H23NO4
- Purity: ≥95%
- Container Type: 250 mL HDPE
- Pack Size: 50 g
- Net Weight: 50 g
- Gross Weight: 89.8 g
- Commodity Code: 29242970
- Country Of Origin: China
- IUPAC: (S)-2-((((9H-fluoren-9-yl)methoxy)carbonyl)(methyl)amino)pentanoic acid
- SMILES: CCC[C@H](N(C(OCC1C2=CC=CC=C2C3=CC=CC=C31)=O)C)C(O)=O
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Medchemexpress LLC Mal-Val-Ala-Pab-N So2Me 10Mg | HY-159072-10MG
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Mal-Val-Ala-Pab-N So2Me 10Mg
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Medchemexpress LLC Mal-VC-PAB-PNP |10mg
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Mal-VC-PAB-PNP is a cleavable ADC linker Mal-VC-PAB-PNP can be used in the synthesis of antibody-drug conjugates (ADCs)[1]
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Medchemexpress LLC Boc-Val-Pro-OH 5g
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Boc-Val-Pro-OH is a biochemical reagent that can be used as a biological material or organic compound for life science related research
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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