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Various organic compounds consisting of carbon, hydrogen, and oxygen atoms that are found in foods and living tissues; typically broken down to release energy; includes sugars, sugar alcohols, sugar acids and derivatives, glycosyl compounds, and more.
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PDGF R protein is integral in embryonic development and regulates cell proliferation survival differentiation chemotaxis migration and vascular development It crucially recruits pericytes and smooth muscle cells to the endothelium promoting vascular smooth muscle cell migration and neointimal formation at the site of injury PDGF R beta Protein Human (HEK293 C-His-Avi) is the recombinant human-derived PDGF R beta protein expressed by HEK293 with C-His C-Avi labeled tag
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The SP-D protein plays a critical role in the lung s defense mechanisms against inhaled microorganisms organic antigens and toxins This multifunctional protein interacts with a variety of compounds including bacterial lipopolysaccharides oligosaccharides and fatty acids to modulate leukocyte activity in immune responses SP-D Protein Rhesus Macaque (HEK293 His) is the recombinant Rhesus Macaque-derived SP-D protein expressed by HEK293 with C-His labeled tag
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IKB beta/NFKBIB protein effectively inhibits NF-kappa-B and prevents NF-kappa-B activation by forming a cytoplasmic complex After cell stimulation the non-phosphorylated form is resynthesized binds to NF-kappa-B aids nuclear transport and protects NF-kappa-B from NFKBIA-dependent inactivation IKB beta/NFKBIB Protein Human (His) is the recombinant human-derived IKB beta/NFKBIB protein expressed by E coli with N-6 His labeled tag
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TGFBR2/TGF-beta RII Protein collaborates with TGFBR1 to form a dedicated receptor for TGFB1 TGFB2 and TGFB3 It serves as a signal transducer orchestrating diverse physiological and pathological processes including cell cycle regulation mesenchymal cell dynamics wound healing matrix production immunosuppression and carcinogenesis Upon cytokine binding the receptor complex activates TGFBR1 through TGFBR2 phosphorylation initiating the canonical SMAD-dependent TGF-beta signaling cascade Additionally TGFBR2 participates in non-canonical SMAD-independent pathways TGFBR2/TGF-beta RII Protein Rhesus Macaque (HEK293 Fc) is the recombinant Rhesus Macaque-derived TGFBR2/TGF-beta RII protein expressed by HEK293 with C-hFc labeled tag
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A pharmacologically active flavonol glucuronide; reduced rat immobility time in the forced swim test (0.6 mg/kg); reduced stress-induced hyperthermia in mice (1.2 mg/kg)
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