Carbohydrates
Apexbio Technology LLC Pamidronate Disodium 57248-88-1 50mg
Pamidronate Disodium (CAS 57248-88-1) is a small-molecule inhibitor targeting osteoclastic bone resorption It is designed to inhibit osteoclast-mediated bone degradation thereby regulating bone metabolism Pamidronate Disodium exerts its biological activity primarily through selective binding to hydroxyapatite crystals in bone followed by suppression of osteoclast activity and induction of osteoclast apoptosis In in vitro studies Pamidronate Disodium demonstrates inhibitory activity on osteoclastic bone resorption with an IC50 in the micromolar range (varying according to experimental conditions) Based on these pharmacological properties Pamidronate Disodium holds research potential in studies of bone density disorders osteoporosis hypercalcemia of malignancy and metastatic bone diseases
Medchemexpress LLC Norbinaltorphimine dihydrochloride | 113158-34-2 | MFCD00069374 | >98.0% | 734.71 g/mol | C40H45Cl2N3O6 | 1 ML
Norbinaltorphimine dihydrochloride is a selective κ-opioid receptor antagonist used in pharmacology research to probe kappa opioid receptor function. The dihydrochloride salt has CAS 113158-34-2 and a molecular weight of 734.71 g/mol; it is typically supplied at high purity for in vitro studies and is available as a ready-to-use 10 mM solution in DMSO.
- Selective kappa-opioid receptor antagonist for receptor pharmacology studies.
- Supplied as a dihydrochloride salt for improved solubility.
- High purity suitable for in vitro assays.
- Available as ready-to-use solution (10 mM) to simplify dosing.
- Store sealed, protect from moisture, and keep solution aliquots frozen.
Medchemexpress LLC Hederacoside D | 760961-03-3 | 99.5% | 1075.24 | 25 MG
Hederacoside D is one of the bioactive saponins from Hedera helix, playing pivotal roles in the overall biological activity. It is intended for research use only.
- Appearence: Solid
- Color: White to off-white
- Structure classification: Terpenoids, Triterpenes
- Initial source: Plants, Araliaceae, Hedera nepalensis K. Koch var. sinensis (Tobl.) Rehd.
- Solubility: In DMSO: 100 mg/mL (93.00 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
- Pharmacokinetic behavior successfully applied in rats after oral and intravenous administration.
Cell Signaling Technology Cleaved Caspase-9 (Asp353) Antibody 100 ul
Cleaved Caspase-9 (Asp353) Antibody 100 ul
Medchemexpress LLC Fluorescein Di-β-D-Glucuronide | 134869-04-8 | HY-D1460 | 96.6% | 684.55 | 5 MG
Fluorescein Di-β-D-Glucuronide is a fluorescent probe used for non-invasive imaging of intestinal bacterial β-glucuronidase activity in nude mice. It reveals the in vitro and in vivo activity of intestinal bacterial β-glucuronidase, facilitating pharmacodynamic studies of specific bacterial β-glucuronidase inhibitors in animal studies.
- Fluorescent probe
- Utilized for non-invasive imaging of intestinal bacterial β-glucuronidase activity
- Reveals in vitro and in vivo activity of intestinal bacterial β-glucuronidase
- Facilitates pharmacodynamic studies of specific bacterial β-glucuronidase inhibitors
- Classified as Fluorescent Dye, Enzyme Labeling, Protease Substrate
- Relevant to Disease Areas: Infection, β-glucuronidase, Bacterial
Cell Signaling Technology Phospho-PDGF Receptor alpha T
Phospho-PDGF Receptor alpha (Tyr762) (D9B1N) Rabbit mAb 100 ul
