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Various organic compounds consisting of carbon, hydrogen, and oxygen atoms that are found in foods and living tissues; typically broken down to release energy; includes sugars, sugar alcohols, sugar acids and derivatives, glycosyl compounds, and more.
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Integrin V beta 5 proteins specifically the -V (ITGAV) subunit are multifunctional receptors for ligands such as vitronectin and fibronectin and recognize RGD sequences ITGAV ITGB3 binds fractalkine and acts as a coreceptor in CX3CR1-dependent signaling Integrin alpha V beta 8 Protein Human (HEK293 His solution) is a recombinant protein dimer complex containing human-derived Integrin alpha V beta 8 protein expressed by HEK293 with C-His labeled tag Integrin alpha V beta 8 Protein Human (HEK293 His solution) has molecular weight of 187 95 kDa
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Integrin -8/ -1 coordinates the recruitment of mesenchymal cells during renal organogenesis and recognizes RGD sequences in ligands such as TNC FN1 SPP1 TGFB1 TGFB3 and VTN It plays a role in multiple cellular interactions critical for organogenesis including NPNT as a functional ligand in nephrogenesis Integrin alpha 8 beta 1 Protein Human (HEK293 His) is a recombinant protein dimer complex containing human-derived Integrin alpha 8 beta 1 protein expressed by HEK293 with C-His labeled tag Integrin alpha 8 beta 1 Protein Human (HEK293 His) has molecular weight of 120-140 kDa 100-120 kDa respectively
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Integrin alpha V beta 6 Protein Human (HEK293 His-Avi) is a recombinant protein dimer complex containing human-derived Integrin alpha V beta 6 protein expressed by HEK293 with C-His C-Avi labeled tag Integrin alpha V beta 6 Protein Human (HEK293 His-Avi) has molecular weight of 90-150 kDa
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Cytochalasin D is a selective inhibitor of actin polymerization with a reported IC50 value of approximately 25 nM It exerts its biological effect by disrupting the formation and stability of actin filaments thereby influencing cellular processes dependent on cytoskeletal organization Through this mechanistic action Cytochalasin D induces cell cycle arrest at the G1-S transition via activation of p53-related signaling pathways In neuronal studies treatment with Cytochalasin D interferes with filopodial and lamellipodial dynamics by limiting protrusion elongation Additionally in vitro investigations demonstrated its utility in the study of virus-host interactions where blockade of actin polymerization inhibits pathogen entry and replication making Cytochalasin D a relevant reagent in cellular biology and virology research
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CDK1/Cyc B-IN-1 is a small-molecule inhibitor selective for the CDK1-cyclin B kinase complex. It inhibits CDK1-cyclin B activity (reported IC50 ≈97 nM) and induces G2/M cell-cycle arrest and apoptosis in cancer cell lines. The compound is supplied as a solid with high purity and is used in biochemical and cellular studies of cell-cycle regulation.
Selective CDK1-cyclin B inhibitor with reported IC50 ≈97 nM.
Induces G2/M cell-cycle arrest and apoptosis in cell lines.
Suitable for biochemical kinase assays and cell-based studies.
High supplied purity for reproducible results.
Soluble in DMSO at 100 mg/mL; use newly opened DMSO.
Stable as a powder under recommended cold storage conditions.
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4-Methylumbelliferyl-α-D-Glucopyranoside (4-Methylumbelliferyl-α-D-Glucose) is a fluorescent substrate for α-glucosidase. It releases the fluorescent moiety 4-methylumbelliferyl (4-MU) upon cleavage, which exhibits pH-dependent fluorescence excitation. This compound can be utilized as a biomarker for Fabry and Pompe diseases to quantify α-glucosidase activity in infant blood spot samples.
Fluorescent substrate for alpha-glucosidase
Releases 4-methylumbelliferyl (4-MU) upon cleavage
4-MU has pH-dependent fluorescence excitation activity
Excitation wavelengths are 320 nm at low pH (1.97-6.72) and 360 nm at high pH (7.12-10.3)
Emission wavelength increases with decreasing pH, ranging from 445-455 nm
Useful as a biomarker for Fabry and Pompe diseases
Quantifies alpha-glucosidase activity in infant blood spot samples
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EPI-589 is a redox-active small-molecule neuroprotective compound used in research on oxidative stress and neurodegenerative disorders. Supplied as a light yellow powder, it is formulated for both in vitro and in vivo experimentation and is readily soluble in DMSO with recommended vehicle formulations for animal dosing. The compound is characterized and shelf-stable under appropriate storage conditions.
High purity: 99.3%.
Chemical formula: C14H19NO4.
Molecular weight: 265.30 g/mol.
Form: solid powder, light yellow to yellow.
In vitro solubility: DMSO 100 mg/mL.
Recommended in vivo vehicles and clear solution ≥ 2.5 mg/mL.
Storage: powder at -20°C (long term) or 4°C (short term).
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Premade antibiotic solutions are ready-to-use as a supplement for your tissue culture, bacteria media or other specific needs. Antibiotics are often used in cell culture to prevent contamination, maintain aseptic conditions, or select for cells containing genetic modifications.
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Gentamicin is a broad-spectrum aminoglycoside antibiotic effective against gram-negative and gram-positive species. In addition, gentamicin exhibits antimicrobial properties against species resistant to tetracycline, colistin, kanamycin, and chloramphenicol.
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ABT-418 hydrochloride is the hydrochloride salt of a selective neuronal nicotinic acetylcholine receptor (nAChR) agonist used for preclinical research. It is supplied as a light brown to brown solid, with characterized purity and solubility suitable for formulation and biological testing.