Carbohydrates
Medchemexpress LLC (D)-PPA 1 TFA | 99.3% | 1669.67 | 5 MG
(D)-PPA 1 TFA is a hydrolysis-resistant d-peptide antagonist and a potent PD-1/PD-L1 inhibitor. It binds to PD-1 with an affinity of 0.51 μM and demonstrates both in vitro and in vivo efficacy, making it suitable for cancer immunotherapy research.
- Hydrolysis-resistant d-peptide antagonist.
- Potent PD-1/PD-L1 inhibitor.
- Binds to PD-1 with 0.51 μM affinity.
- Demonstrates in vitro and in vivo efficacy.
- Blocks the interaction between PD-1/PD-L1 at 1.0 mg/mL.
- Does not directly kill tumor cells or affect CT26 cell growth (3.125-100 μM over 24-48 hours in vitro).
- Inhibits CT26 tumor growth in mice (2 mg/kg; s.c. or i.p.; once daily for 7 d).
- Can target tumor tissue in CT26-tumor-bearing mice (40 μg/mouse in 200 μL; i.v.; single dose).
- High purity: 99.3%.
- Appearance: Solid, white to off-white.
![eMolecules Medchem Express / Chitin synthase inhibitor 4 / 5mg / 784544142 / HY-150686 / / 2755847-31-3 / [null] / 346.365 / C20H15FN4O](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502472347.JPG-250.jpg)
eMolecules Medchem Express / Chitin synthase inhibitor 4 / 5mg / 784544142 / HY-150686 / / 2755847-31-3 / [null] / 346.365 / C20H15FN4O
Medchem Express / Chitin synthase inhibitor 4 / 5mg / 784544142 / HY-150686 / / 2755847-31-3 / [null] / 346.365 / C20H15FN4O
Medchemexpress LLC Cathepsin D Human 5ug | 5ug
Cathepsin D protein is an acidic protease that actively participates in intracellular protein breakdown Studies have shown that it is critical in the processing of amyloid precursor protein (APP) with ADAM30-mediated cleavage and activation leading to APP degradation Cathepsin D Protein Human (HEK293 C-His) is the recombinant human-derived Cathepsin D protein expressed by HEK293 with C-6 His labeled tag
Medchemexpress LLC TNF-alpha/TNFSF2 Mo 2ug
Recombinant mouse TNF-alpha/TNFSF2 protein (147 aa), corresponding to residues D89-L235 of mouse TNF-α, expressed in E. coli and supplied lyophilized. The product is >95% pure by reducing SDS-PAGE, has an apparent molecular weight of ~17.0 kDa, and is functionally validated in an L-929 cytotoxicity assay (ED50 = 1.616 pg/mL), making it suitable for signaling, bioactivity, and cytokine functional studies.
- Produced in E. coli for efficient bacterial expression.
- Purity greater than 95% by reducing SDS-PAGE.
- Corresponds to amino acids D89-L235 of mouse TNF-α (147 aa).
- Apparent molecular weight of approximately 17.0 kDa.
- Validated bioactivity in L-929 cytotoxicity assay (ED50 = 1.616 pg/mL).
- Supplied lyophilized for long-term storage and easy reconstitution.
Medchemexpress LLC Beta-NGF Mouse 110 2ug
Recombinant mouse beta nerve growth factor (β-NGF) is provided as a 110-amino-acid His-tagged protein corresponding to residues M130-R239. Produced in Escherichia coli and purified to >95% by reducing SDS-PAGE, the protein is supplied in small vial sizes for in-lab research, with storage and handling guidance to preserve activity. Intended for research use only.
Cell Signaling Technology SKAR alpha/beta (D65E8) XP(R) Rabbit mAb 20 ul
SKAR alpha/beta (D65E8) XP(R) Rabbit mAb 20 ul
Medchemexpress LLC 3-Deazaadenosine | 6736-58-9 | ≥99.0% | 266.26 | 1 MG
3-Deazaadenosine is an inhibitor of S-adenosylhomocysteine hydrolase (SAHH), with a Ki of 3.9 μM. It exhibits anti-inflammatory, anti-proliferative, and anti-HIV activities.
- Inhibitor of S-adenosylhomocysteine hydrolase (SAHH)
- Anti-inflammatory activity
- Anti-proliferative activity
- Anti-HIV activity
Cell Signaling Technology beta-Amyloid (1-37) (D2A6H) Rabbit mAb 20 ul
beta-Amyloid (1-37) (D2A6H) Rabbit mAb 20 ul
Medchemexpress LLC 3-Deazaadenosine hydrochloride | 86583-19-9 | 99.67% | 302.72 | 5 MG
3-Deazaadenosine hydrochloride | 86583-19-9 | 99.67% | 302.72 | 5 MG
Medchemexpress LLC Phospho-Glycogen synthase 1/GYS1 (S641) Antibody (YA195) | 81 kDa | 10 UL
This rabbit-derived, non-conjugated IgG monoclonal antibody targets Phospho-Glycogen synthase 1/GYS1 (S641) and is intended for research use only. It is suitable for applications such as Western Blotting, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, and Immunoprecipitation.
- Recombinant, monoclonal antibody
- Targets Phospho-Glycogen synthase 1/GYS1 (S641)
- Species reactivity: human, mouse, rat
- Predicted and observed molecular weight: 81 kDa
- Protein A affinity purified
- Supplied in 1*TBS (pH7.4), 0.05% BSA and 40% Glycerol with 0.05% Sodium Azide
- Store at -20°C for 1 year; avoid repeated freeze/thaw cycles
Medchemexpress LLC Latent TGF beta 1/TG 10ug
Latent TGF beta 1 (latent TGFB1) is the inactive form of TGF-B1 Latent TGF beta 1 associates with the extracellular matrix (ECM) via LTBP LTBPs are components of the ECM so that the proteolytic cleavage of LTBP can lead to the release of latent TGF-beta 1 from the matrix Besides the proteolytic cleavage and liberation of active TGFB1 is performed by BMP-1 by a variety of matrix metalloproteinases (MMPs)[1][3] Latent TGF beta 1/TGFB1 Protein Rat (HEK293 His) is the recombinant rat-derived Latent TGF beta 1/TGFB1 protein expressed by HEK293 with C-His labeled tag
Medchemexpress LLC 4 6-O-Benzylidene-D- 10g | 30688-66-5 | 268.26 g/mol | C13H16O6 | 10 G
4,6-O-Benzylidene-D-glucose (CAS 30688-66-5) is a benzaldehyde-derived glucose derivative reported to have anticancer activity and commonly used as an intermediate in carbohydrate synthesis and related biochemical research. Supplied as a white to off-white solid for research use.
- Used as a synthetic intermediate in carbohydrate and glycoside chemistry.
- Reported anticancer effects documented in literature.
- White to off-white solid suitable for laboratory handling and storage.
- Molecular formula C13H16O6; molecular weight 268.26 g/mol.
- Available in solid package sizes including 10 G.
Cayman Chemical UDPsodIum salt hydrate 500mg
The diphosphate of uridine; a specific agonist of the P2Y purinoceptor P2Y6 (EC50 = 13 nM for human P2Y6), stimulating the production of inflammatory mediators, phagocytosis, and vasoconstriction; an antagonist of P2Y14