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Various organic compounds consisting of carbon, hydrogen, and oxygen atoms that are found in foods and living tissues; typically broken down to release energy; includes sugars, sugar alcohols, sugar acids and derivatives, glycosyl compounds, and more.
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PROTAC BET Degrader-10 (dBET37) is a potent BET protein BRD4 degrader, connected by ligands for Cereblon and BRD4, with a DC50 of 49 nM. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
Potent BET protein BRD4 degrader
Connects ligands for Cereblon and BRD4
Utilizes the ubiquitin-proteasome system
Selectively degrades target proteins
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Dipotassium tetrachloroplatinate is an important reagent for the preparation of other platinum coordination complexes. It can be used as a radiosensitizer to enhance the killing effect of hyperthermia, serves as a catalyst, and exhibits antitumor activity. For research use only.
Enhances the killing effect of hyperthermia.
Serves as a catalyst.
Exhibits antitumor activity.
For research use only.
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PLX5622 in AIN-76A Diet (1200 ppm) is specifically designed for microglia clearance research. This diet contains 1200 mg of PLX5622 per kilogram of AIN-76 diet and has been verified for its suitability in microglia function studies in both healthy and diseased states. A complimentary PLX5622-Free AIN-76A Diet is also provided to serve as a control group for comparative studies.
Contains 1200 mg of PLX5622 per Kg of AIN-76 diet.
Used for microglia clearance studies.
Suitable for microglia function research.
Provided with a complimentary control diet.
Pharmacological manipulation of microglia can provide insights into brain functions.
Administered via ad libitum feeding.
The diet is blue in color.
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Galactose 1-phosphate-¹³C-1 (potassium) is the ¹³C labeled Galactose 1-phosphate Potassium salt. Galactose 1-phosphate Potassium salt is an intermediate in the galactose metabolism and nucleotide sugar. Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.
Intermediate in galactose metabolism and nucleotide sugar
Suitable for tracer applications in drug development
Potential to affect pharmacokinetic and metabolic profiles of drugs
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Also available in 5 mg, 10 mg, 25 mg, 50 mg, 100 mg, 500 mg and bulk. Please contact Fisher for quotes. beta-Nicotyrine is a tobacco alkaloids Metabolite in the liver. Purity 100%
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L-Glucose-13C6 is C13-labeled L-Glucose, an enantiomer of D-glucose that enhances food intake. It is largely used as a tracer for quantitation during the drug development process due to the incorporation of stable heavy isotopes. It can also serve as an internal standard for quantitative analysis.
Used as a tracer
Used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
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