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Various organic compounds consisting of carbon, hydrogen, and oxygen atoms that are found in foods and living tissues; typically broken down to release energy; includes sugars, sugar alcohols, sugar acids and derivatives, glycosyl compounds, and more.
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IL-20R beta Protein (IL20RB) is the beta subunit of IL-20 receptor forms functional heterodimers with different subunit protein and involves in STAT3 activation pathway[1] The IL-20RA/IL-20RB dimer is a receptor for IL-19 IL-20 and IL-24 The IL-22RA1/IL-20RB dimer is a receptor for IL-20 and IL-24[2] IL-20R beta Protein is consists of 308 amino acids (M1-T308) with a transmembrane domain (226-249 a a ) IL-20R beta Protein Rat (HEK293 Fc) is produced in HEK293 cells with a C-Terminal hFc-tag
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IFN-beta Protein is an immunomodulatory cytokine of the type 1 interferon family IFN-beta Protein reduces joint inflammation by inhibiting the RANKL-c-Fos signaling pathway IFN-beta Protein regulates mitochondrial fission through STAT5 PGAM5 and Drp1 to rescue neurodegeneration IFN-beta Protein Rhesus Macaque (HEK293 Fc) is the recombinant Rhesus Macaque-derived IFN-beta protein expressed by HEK293 with C-mFc labeled tag
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IFN-beta is a secretory cytokine produced by cells under viral infection or nucleic acid stimulation IFN binds to cell surface heterodimeric receptors (IFNAR1/IFNAR2) activates the JAK-STAT signaling pathway and induces the expression of interferon-stimulated genes (ISGs) (such as PKR 2 5 -OAS) IFN-beta inhibits viral proliferation regulates immune responses (such as inhibiting Th1 cell polarization reducing pro-inflammatory cytokine secretion) inhibits the proliferation of vascular smooth muscle cells and tumor cells IFN-beta has anti-atherosclerotic and vascular remodeling effects Mouse (HEK293) is the recombinant mouse-derived IFN-beta protein expressed by HEK293 with tag free
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Integrin alpha V beta 6 Protein Human (HEK293 His) is a recombinant protein dimer complex containing human-derived Integrin alpha V beta 6 protein expressed by HEK293 with C-His labeled tag Integrin alpha V beta 6 Protein Human (HEK293 His) has molecular weight of 130 95 KDa respectively
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IKB beta/NFKBIB protein effectively inhibits NF-kappa-B and prevents NF-kappa-B activation by forming a cytoplasmic complex After cell stimulation the non-phosphorylated form is resynthesized binds to NF-kappa-B aids nuclear transport and protects NF-kappa-B from NFKBIA-dependent inactivation IKB beta/NFKBIB Protein Human (His) is the recombinant human-derived IKB beta/NFKBIB protein expressed by E coli with N-6 His labeled tag
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PGLYRP4/PGRP-I beta protein is a model receptor that binds to the cell wall peptide peptidoglycan (PGN) in Gram-positive bacteria and exerts bactericidal activity by interfering with peptidoglycan biosynthesis Its antimicrobial properties extend to Gram-negative bacteria although it also binds to them PGLYRP4/PGRP-I beta Protein Human (HEK293 His) is the recombinant human-derived PGLYRP4/PGRP-I beta protein expressed by HEK293 with C-His labeled tag
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Complement factor D also known as Adipsin plays a crucial role in the alternative pathway of the complement system and when complexed with factor C3b it cleaves factor B This cleavage activates the C3bbb complex converting it to the C3 convertase of the alternative pathway Complement Factor D/Adipsin Protein Human (HEK293 His Solution) is the recombinant human-derived Complement Factor D/Adipsin protein expressed by HEK293 with C-10 His labeled tag
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