Carbohydrates
Medchemexpress LLC Rehmannioside D | 81720-08-3 | MFCD30478904 | 99.9% | 686.61 g/mol | C27H42O20 | 10 MG
Rehmannioside D is a carotenoid glycoside isolated from the roots of Rehmannia glutinosa. Supplied as a 10 mg powder research reagent, it is used as an analytical standard and in biochemical studies of antioxidant activity and reactive oxygen species (ROS). Molecular formula C27H42O20; molecular weight 686.61 g/mol.
- Purity 99.9% suitable for analytical applications.
- Powder form, stable under recommended storage conditions.
- Useful in antioxidant and ROS pathway studies.
- Provided as a 10 MG vial for small-scale experiments.
- Identified by CAS number 81720-08-3 for unambiguous chemical identification.
Medchemexpress LLC D-Glucose, O-α-D-glucopyranosyl-(1→6)-O-α-D-glucopyranosyl-(1→4)- | 33401-87-5 | 99.95% | 504.44 | 25 MG
D-Panose is an oligosaccharide composed of glucose units linked by specific glycosidic bonds. It is a PAN-type oligosaccharide and a food ingredient based on isomaltooligosaccharides (IMOs). It can be detected with high sensitivity in SALDI-MS using magnesium oxide nanoparticles as the matrix.
- Composed of glucose units.
- PAN-type oligosaccharide.
- Food ingredient based on isomaltooligosaccharides (IMOs).
- High sensitivity detection in SALDI-MS.
- For research use only.
Medchemexpress LLC PROTAC BET degrader-1 | 2093386-22-0 | 99.4% | 871.90 g·mol⁻¹ | C44H45N11O9 | 25 MG
PROTAC BET Degrader-1 is a proteolysis-targeting chimera that links Cereblon and BET ligands to induce degradation of BET family proteins BRD2, BRD3, and BRD4 at low concentrations. It is supplied as a light yellow solid for research use only.
- Degrades BRD2, BRD3, and BRD4 at low nanomolar concentrations.
- High purity suitable for biochemical and cell-based assays.
- Readily soluble in DMSO; protocols provided for in vivo formulations.
- Stable when stored as powder at -20 °C and in solvent at -80 °C.
Medchemexpress LLC Integrin alpha V bet 50ug
Integrin V beta 5 proteins specifically the -V (ITGAV) subunit are multifunctional receptors for ligands such as vitronectin and fibronectin and recognize RGD sequences ITGAV ITGB3 binds fractalkine and acts as a coreceptor in CX3CR1-dependent signaling Integrin alpha V beta 8 Protein Human (HEK293 His solution) is a recombinant protein dimer complex containing human-derived Integrin alpha V beta 8 protein expressed by HEK293 with C-His labeled tag Integrin alpha V beta 8 Protein Human (HEK293 His solution) has molecular weight of 187 95 kDa
Medchemexpress LLC OBI-992 drug-linker | 3039487-10-7 | 96.6% | 2173.46 | 1 MG
OBI-992 drug-linker is a drug-linker conjugate composed of a TOP I inhibitor Exatecan (HY-13631) and a linker. It exhibits antitumor property in mouse models and can be used for the synthesis of ADC OBI-992.
- Composed of a TOP I inhibitor and a linker
- Exhibits antitumor properties in mouse models
- Can be used for the synthesis of ADC OBI-992
Medchemexpress LLC AMG 333 | 1416799-28-4 | 99.8% | 453.32 | 25 MG
AMG 333 is an orally active and highly selective TRPM8 antagonist with an IC50 of 13 nM. It dose-dependently inhibits wet-dog shake behavior and blocks blood pressure elevation in rat models, making it a clinical candidate for the treatment of migraine.
- Orally active and highly selective TRPM8 antagonist
- Dose-dependently inhibits wet-dog shake behavior in the Icilin-induced wet-dog shake Sprague-Dawley rat model
- Dose-dependently blocks blood pressure elevation in the cold stimulation-induced blood pressure elevation Sprague-Dawley rat model
- A clinical candidate for the treatment of migraine
Alkali Scientific 4 Methylumbelliferyl β L Fucopyranoside, 100 Milligrams
Methylumbelliferyl Fucopyranoside is a high-purity reagent used in biochemical analysis to evaluate the activity of enzymes that hydrolyze fucose-containing substrates. This 100mg preparation is useful in enzyme assays aimed at studying fucosidases, which play a key role in glycosylation and glycosaminoglycan metabolism. It is commonly used in research on carbohydrate metabolism, specifically in glycosyltransferase assays and enzyme-linked tests. Methylumbelliferyl Fucopyranoside is an essential reagent for labs studying the biochemical pathways of fucose and its role in both plant and animal systems.
Medchemexpress LLC Platycodin D | 58479-68-8 | 1225.32 | 25 MG
Platycodin D is a saponin isolated from *Platycodon grandiflorus*. It acts as an activator of AMPKα and possesses anti-obesity properties. The WNT/β-catenin pathway mediates its anti-adipogenic effect.
- Saponin isolated from *Platycodon grandiflorus*.
- Activator of AMPKα.
- Anti-obesity property.
- WNT/β-catenin pathway mediates its anti-adipogenic effect.
Medchemexpress LLC Integrin alpha 8 bet 5ug
Integrin -8/ -1 coordinates the recruitment of mesenchymal cells during renal organogenesis and recognizes RGD sequences in ligands such as TNC FN1 SPP1 TGFB1 TGFB3 and VTN It plays a role in multiple cellular interactions critical for organogenesis including NPNT as a functional ligand in nephrogenesis Integrin alpha 8 beta 1 Protein Human (HEK293 His) is a recombinant protein dimer complex containing human-derived Integrin alpha 8 beta 1 protein expressed by HEK293 with C-His labeled tag Integrin alpha 8 beta 1 Protein Human (HEK293 His) has molecular weight of 120-140 kDa 100-120 kDa respectively
Medchemexpress LLC Benzamide, N-[[(5-chloro-2-pyridinyl)amino]thioxomethyl]-3-nitro-4-(1-piperidinyl)- | 838810-96-1 | 98.0% | 25 MG
MAC-545496 is a nanomolar inhibitor of glycopeptide-resistance-associated protein R (GraR). It demonstrates strong binding affinity to the full-length GraR protein (Kd ≤ 0.1 nM) and functions as an antivirulence agent, effectively reversing β-lactam resistance in Methicillin-resistant strains (MRSA).
- Potent synergism with cefuroxime
- Reduces β-lactam MIC against S. aureus USA300
- Enhances activity against S. aureus clinical isolates
- Potentiates effects against various circulating MRSA strains
- Synergizes with antimicrobial peptides colistin and polymyxin B
- Inhibits mprF expression
- Inhibits citrate-induced biofilm formation
- Effective as monotherapy for MRSA-infected larvae
- Increases survival in drug-treated larvae
- Correlates with concentration-dependent bacterial killing
Medchemexpress LLC D-KLVFFA | 342877-55-8 | 99.3% | 723.90 | 10 MG
D-KLVFFA is an inhibitor of Amyloid-β assembly, with an IC50 of 2.6 μM. It can be utilized in Alzheimer's disease studies, offering insights into amyloid-beta aggregation pathways.
- Inhibits amyloid-β assembly
- Useful in Alzheimer's disease studies
- Molecular weight of 723.90
- Purity of 99.3%
Medchemexpress LLC Rose-β-D-gal | 138182-21-5 | MFCD00467206 | 99.7% | 329.73 g/mol | C14H16ClNO6 | 25 MG
Rose-β-D-Gal is a chromogenic β-galactosidase substrate that produces a pink/magenta color upon enzymatic cleavage. It is used to detect β-gal activity in biochemical and cell-based assays where a visible color change is required.
- Produces a pink/magenta chromogenic signal for β-gal activity detection.
- Suitable for enzymatic assays and staining applications.
- High reported purity (99.71%) for consistent performance.
- Solid reagent supplied in small milligram quantities for research use.
- Compatible with colorimetric readouts and microscopy.
Medchemexpress LLC Ethyl glucuronide | 17685-04-0 | 99.2% | 222.19 | 1 ML
Ethyl glucuronide is an endogenous metabolite of ethanol. It serves as a biomarker for ethanol exposure, accumulating in hair and reflecting alcohol intake over time. It is also an agonist for TLR4.
- Endogenous metabolite
- Biomarker for ethanol exposure
- Agonist for TLR4
- Appearance: Solid, white to off-white
- Storage: -20°C, protect from light, stored under nitrogen. In solvent: -80°C for 6 months; -20°C for 1 month (protect from light, stored under nitrogen).
- Useful in research for studying ethanol exposure and its effects
- Can be used to block the formation of the TLR4-MD2 complex and stimulate the expression of TLR4-dependent SEAP protein in HEK-TLR4 cells
- Has been shown to reduce tactile threshold and induce hyperalgesia in Sprague-Dawley rat models
Medchemexpress LLC Semaglutide-FITC (semaglutide-Lys(FITC)) | 4502.96 | 25 MG
Semaglutide-FITC is a FITC-labeled semaglutide, a GLP-1R agonist. It is used to directly track the distribution, cellular uptake, and transmembrane transport processes of vesicles. It can also be employed to study the movement and penetration ability of mixed vesicles in porcine intestinal mucus in vitro.
- FITC-labeled semaglutide (a GLP-1R agonist).
- Directly track the distribution, cellular uptake, and transmembrane transport process of vesicles via fluorescence imaging and flow cytometry.
- Study movement and penetration ability of mixed vesicles in porcine intestinal mucus in vitro.
Medchemexpress LLC Cdk1/Cyc B-IN-1 | 2459916-56-2 | 98.5% | 353.85 | 50 MG
CDK1/Cyc B-IN-1 (Compound 5) is a selective CDK1/Cyc B complex inhibitor with an IC50 of 97 nM. It triggers apoptosis and G2/M cell cycle arrest and demonstrates broad-spectrum cytotoxic action against cancer cell lines. In vitro, it is soluble in DMSO at 100 mg/mL.
- Induces apoptosis and G2/M cell cycle arrest
- Exhibits cytotoxic activity against HCT-116 cells (IC50 of 5.33 ± 0.69 μM)
- Exhibits cytotoxic activity against WI-38 cells (IC50 of 21.69 ± 1.04 μM)
- Shows antiproliferative activity against various human cancer cell lines