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Estrone sulfate sodium is an inactive endogenous estrogen. It can be converted into Estrone and Estradiol and is a substrate of the OATP1B3 transporter. This compound stimulates the growth of nitrosomethylurea-induced mammary tumors and colony formation of dispersed nitrosomethylurea mammary cells, with conversion to Estrone and Estradiol occurring both in vivo and in vitro.
Can be converted into Estrone and Estradiol.
Substrate of the OATP1B3 transporter.
Stimulates mammary tumor growth in ovariectomized rats.
Applicable to breast cancer-related research.
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Hydrocortisone Acetate (Cortisol 21-acetate) is the synthetic acetate salt form of hydrocortisone a corticosteroid with anti-inflammatory and immunosuppressive properties
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A3551 is a small molecule compound designed to modulate specific cellular signaling pathways implicated in various pathological states It functions primarily by targeting kinase-mediated pathways thereby influencing intracellular signaling cascades associated with cell proliferation and differentiation Due to its pathway-specific mechanism of action A3551 is valuable for biomedical research examining signal transduction mechanisms oncogenesis processes and potential therapeutic intervention strategies
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Abscisic acid (Dormin CAS 21293-29-8) is a plant hormone involved in regulating plant growth development and stress responses Its activity includes mediating seed dormancy germination control lateral root formation and adaptive responses to abiotic stress Mechanistically ABA influences histone H2B ubiquitination and chromatin remodeling processes thereby modulating gene expression during seed maturation and under environmental stress ABA signaling also alters cellular redox status by enhancing synthesis of antioxidants such as -tocopherol and L-ascorbate It is widely utilized in plant biology research to study stress physiology developmental biology and epigenetic gene regulation
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1-Methylguanosine-d3 (N1-Methylguanosine-d3) is a deuterium labeled form of 1-Methylguanosine, a methylated nucleoside derived from RNA degradation and identified as a tumour marker. This compound is for research use only.
Can be used as a tracer.
Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
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(rel)-β-Tocopherol is a relative configuration of β-Tocopherol. β-Tocopherol is a lipid-soluble form of vitamin E that exhibits antioxidant activity. It is intended for research use only and not for human consumption.
β-Tocopherol (50 μM, 48 hours) has been observed to slightly inhibit the proliferation of A7r5 cells (10% inhibition) and CHO cells (20% inhibition), while showing no inhibitory effect on HeLa cells.
It also inhibits PMA-induced adhesion of human erythroleukemia (HEL) cells (11% inhibition) and the expression of integrins α4 and α5 on the cell surface when applied at 50 μM for 24 hours.
Appearance: Solid-Liquid Mixture
Color: Colorless to off-white
In ethanol: 50 mg/mL (119.99 mM); requires sonication.
In a solution of 10% Ethanol, 40% PEG300, 5% Tween-80, and 45% Saline: ≥ 1.25 mg/mL (3.00 mM) as a clear solution.
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17β-estradiol sulfate sodium is the sodium salt of the sulfate metabolite of 17β-estradiol supplied as a solid research reagent. It is used for studies of estrogen metabolism, receptor binding, and neuroactive steroid activity. For research use only; not for human or veterinary use.
Sodium salt of 17β-estradiol sulfate.
High purity (99.0%).
Molecular weight 374.43 g·mol⁻¹.
Chemical formula C18H23NaO5S.
Provided as a white to light yellow solid.
SDS and COA available for quality and safety documentation.
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Lauric acid (143-07-7) is a small-molecule modulator designed to induce apoptosis and inhibit microbial colonization thereby regulating cell viability and inflammatory responses Lauric acid exerts its biological activity primarily through ROS-dependent oxidative stress cell cycle arrest at S and G2/M phases and reduction of intracellular glutathione In cell-based studies lauric acid induces apoptosis in colon carcinoma cells (Caco-2 and IEC-6) and reduces Propionibacterium acnes colonization in animal models Based on these pharmacological properties lauric acid holds research potential in investigating antiproliferative mechanisms in cancer and antimicrobial applications including acne treatment
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