Lipids and Lipid Derivatives
Medchemexpress LLC Iso-VQA-ACC acetate | 99.48% | 625.63 (free base) | 1 MG
iso-VQA-ACC acetate is a substrate for constitutive proteasome, characterized by its molecular formula C29H35N7O9.xC2H4O2 and a molecular weight of 625.63 (free base). This compound has a purity of 99.48% and is commonly identified by its sequence, iso-Val-Gln-Ala-{ACC}. It is primarily used in research involving proteasome and metabolic enzyme/protease pathways.
- Targets proteasome activity for metabolic studies.
- High purity suitable for sensitive research applications.
- Soluble in DMSO at 100 mg/mL, requiring ultrasonic treatment for dissolution.
Medchemexpress LLC 17-hydroxy-11-dehydrocorticosterone | 53-06-5 | 99.3% | 360.44 | 5 G
Cortisone (17-Hydroxy-11-dehydrocorticosterone) is an oxidized metabolite of Cortisol, a Glucocorticoid. It functions as an immunosuppressant and anti-inflammatory agent. At high concentrations, Cortisone can partially interfere with the binding of Glucocorticoid to the Glucocorticoid-receptor. This product is intended for research use only.
- Oxidized metabolite of Cortisol
- Functions as an immunosuppressant
- Acts as an anti-inflammatory agent
- Partially interferes with Glucocorticoid-receptor binding
- For research use only
Medchemexpress LLC Hydrocortisone acepo 10mM 1mL | 74050-20-7 | 460.56 g/mol | C26H36O7 | 1 ML
Hydrocortisone aceponate (hydrocortisone 17-propionate 21-acetate) is a synthetic topical glucocorticoid supplied as an analytical standard for research applications. It is offered as solid material and as a ready-to-use 10 mM solution in DMSO (1 mL). The compound is used in dermatoses and glucocorticoid receptor studies; supplier guidance lists purity and storage conditions.
Medchemexpress LLC Hydrocortisone acepo 10mg | 74050-20-7 | 460.56 g/mol | C26H36O7 | 10 MG
Hydrocortisone aceponate (hydrocortisone 17-propionate 21-acetate) is a potent topical glucocorticoid supplied for research use in studies of dermatoses and glucocorticoid receptor biology.
- Potent topical glucocorticoid for dermatoses research.
- White to off-white powder appearance.
- Purity approximately 99.4% as stated by supplier.
- Chemical formula C26H36O7; molecular weight 460.56 g/mol.
- Available as solids (5 mg, 10 mg, 25 mg, 50 mg) and as a 10 mM solution in DMSO (1 mL).
- Soluble in DMSO (~100 mg/mL); ultrasonic treatment recommended.
- Storage: powder -20°C (stable ~3 years) or 4°C (stable ~2 years); in solvent -80°C (6 months) or -20°C (1 month).
- Intended for research use only; not for human or veterinary use.
Apexbio Technology LLC Dexamethasone acetate 1177-87-3 10mM (in 1mL DMSO)
Dexamethasone acetate a synthetic glucocorticoid acts by binding to glucocorticoid receptors influencing gene transcription to suppress inflammatory and immune responses By modulating cytokine production and inhibiting interleukin (IL) signaling pathways dexamethasone acetate serves as an interleukin receptor modulator Typically applied in research related to inflammation autoimmune diseases and cytokine-mediated cellular events it is extensively utilized in functional assays to understand receptor-ligand interactions signal transduction and therapeutic mechanisms Studies report variable IC50 values depending on cell type and assay conditions with typical IC50 ranges documented from 1-10 nM in receptor binding assays providing a reference concentration range for experimental designs
Medchemexpress LLC Glycocholic acid sodium | 863-57-0 | 487.60 | 100 MG
Glycocholic acid sodium is an orally active bile acid with anticancer activity, targeting against pump resistance-related and non-pump resistance-related pathways. It enhances the cytotoxicity and intracellular accumulation of epirubicin in Caco-2 cells and rat small intestine.
- Increases the cytotoxicity of epirubicin.
- Enhances intracellular accumulation of epirubicin.
- Intensifies epirubicin-induced apoptosis.
- Reduces mRNA expression levels of human intestinal MDR1, MRP1, and MRP2.
- Downregulates MDR1 promoter region.
- Suppresses mRNA expression of Bcl-2.
- Induces mRNA expression of Bax.
- Significantly increases the Bax-to-Bcl-2 ratio.
- Increases mRNA levels of p53, caspase-9 and -3.
- Can control multidrug resistance via modulating P-gp and MRPs.
- Regulates apoptosis-related pathways.
Chem-Impex International, Inc. Glycocholic acid hydrate | 475-31-0 | MFCD06408004 | 1G
Glycocholic acid hydrate, 475-31-0, MFCD06408004, 1G
Arbor Assays 20-Hydroxyecdysone ELISA Kit (5 Plate)
The DetectX 20-Hydroxyecdysone ELISA Kits measure 20-hydroxyecdysone in arthropods and plants.
Medchemexpress LLC DT-2 acetate | 98.6% | 3761.25 | 1 MG
DT-2 is a potent and selective inhibitor of the cGMP-dependent protein kinase (PKG), which inhibits PKG catalyzed phosphorylation with a Ki of 12.5 nM.
- Potent and selective inhibitor of cGMP-dependent protein kinase (PKG).
- Inhibits PKG catalyzed phosphorylation.
- For research use only.
TARGETMOL CHEMICALS INC Exendin-4 acetate 5MG
Also available in 1 mg, 10 mg, 25 mg, 50 mg, 100 mg and bulk. Please contact Fisher for quotes. Exendin-4 acetate is a 39 amino acid peptide.Exendin-4 acetate is a long-acting GLP-1 receptor agonist(IC50 = 3.22 nM). Purity 98.65%
TARGETMOL CHEMICALS INC Nomegestrol acetate 25MG
Also available in 1 mL, 2 mg, 5 mg, 10 mg, 50 mg, 100 mg, 200 mg and bulk. Please contact Fisher for quotes.Nomegestrol acetate is a widely used progestin-like drug,which is characterized as a full agonist at the progesterone receptor Purity 99.93%
Medchemexpress LLC Geranyl acetate | 105-87-3 | 100 G
Geranyl acetate is an acyclic monoterpene ester derived from geraniol. It is widely used in the cosmetics industry due to its pleasant scent and has been shown to induce cell apoptosis. This product appears as a colorless to light yellow liquid.
- Acyclic monoterpene ester
- Derived from geraniol
- Used in cosmetics industry for pleasant scent
- Induces cell apoptosis
- Purity: 99.74%
- Molecular weight: 196.29
- Chemical formula: C12H20O2
- Density: 0.916 g/cm³
- Exhibits significant anti-cancer activity against colo-205 cancer cell line
- Agonist activity at rat TRPA1 (EC50 of 25.8 μM in HEK293 cells)
- Antagonist activity against rat TRPA1 (IC50 of 21.2 μM in HEK293 cells)
Medchemexpress LLC Glycocholic acid-d5 | 2170091-95-7 | 470.65 | 1 MG
Glycocholic acid-d5 is the deuterium labeled Glycocholic acid, which is a bile acid exhibiting anticancer activity by targeting both pump resistance-related and non-pump resistance-related pathways. This compound is intended for research use only.
- This compound can be used as a tracer.
- This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.