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Cortisone acetate (50-04-4) is a glucocorticoid receptor agonist targeting the glucocorticoid receptor It is designed to modulate glucocorticoid signaling thereby regulating gene transcription and downstream immune and inflammatory responses Cortisone acetate exerts its biological activity primarily through enzymatic conversion to cortisol which subsequently activates glucocorticoid receptors to influence cellular stress and inflammatory pathways Based on these pharmacological properties cortisone acetate holds research potential in the investigation of glucocorticoid signaling pathways receptor-mediated transcriptional regulation cellular stress responses and inflammatory condition models
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Cortisone acetate (50-04-4) is a glucocorticoid receptor agonist targeting the glucocorticoid receptor It is designed to modulate glucocorticoid signaling thereby regulating gene transcription and downstream immune and inflammatory responses Cortisone acetate exerts its biological activity primarily through enzymatic conversion to cortisol which subsequently activates glucocorticoid receptors to influence cellular stress and inflammatory pathways Based on these pharmacological properties cortisone acetate holds research potential in the investigation of glucocorticoid signaling pathways receptor-mediated transcriptional regulation cellular stress responses and inflammatory condition models
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
Hydrocortisone aceponate (hydrocortisone 17-propionate 21-acetate) is a synthetic topical glucocorticoid supplied as an analytical standard for research applications. It is offered as solid material and as a ready-to-use 10 mM solution in DMSO (1 mL). The compound is used in dermatoses and glucocorticoid receptor studies; supplier guidance lists purity and storage conditions.
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Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
Hydrocortisone aceponate (hydrocortisone 17-propionate 21-acetate) is a potent topical glucocorticoid supplied for research use in studies of dermatoses and glucocorticoid receptor biology.
Potent topical glucocorticoid for dermatoses research.
White to off-white powder appearance.
Purity approximately 99.4% as stated by supplier.
Chemical formula C26H36O7; molecular weight 460.56 g/mol.
Available as solids (5 mg, 10 mg, 25 mg, 50 mg) and as a 10 mM solution in DMSO (1 mL).
Soluble in DMSO (~100 mg/mL); ultrasonic treatment recommended.
Storage: powder -20°C (stable ~3 years) or 4°C (stable ~2 years); in solvent -80°C (6 months) or -20°C (1 month).
Intended for research use only; not for human or veterinary use.
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Dexamethasone acetate a synthetic glucocorticoid acts by binding to glucocorticoid receptors influencing gene transcription to suppress inflammatory and immune responses By modulating cytokine production and inhibiting interleukin (IL) signaling pathways dexamethasone acetate serves as an interleukin receptor modulator Typically applied in research related to inflammation autoimmune diseases and cytokine-mediated cellular events it is extensively utilized in functional assays to understand receptor-ligand interactions signal transduction and therapeutic mechanisms Studies report variable IC50 values depending on cell type and assay conditions with typical IC50 ranges documented from 1-10 nM in receptor binding assays providing a reference concentration range for experimental designs
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Dexamethasone palmitate (DXP) a lipophilic prodrug of Dexamethasone (DXM) is a glucocorticoid receptor agonist with a 47-fold lower affinity for the glucocorticoid receptor than DXM Dexamethasone palmitate (DXP) exhibits anti-inflammatory activity
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Cortisone is a pregnane steroid hormone and one of main substance released by the body as a reaction to stress It suppresses the immune system thus reducing inflammation and attendant pain and swelling at the site of the injury
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Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
Cortisone acetate analytical standard supplied for research and analytical applications. It is used as a reference material in chromatographic and mass spectrometric assays, supporting qualitative, quantitative, and methodological studies.
Analytical standard for HPLC, GC, and MS
Intended for qualitative and quantitative method development
Purity ≥99.0%
Molecular weight 402.48 g/mol
CAS number 50-04-4
Provided as a 10 mg pack suitable for laboratory use
Exhibits immunosuppressant and anti-inflammatory activity
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