Nucleosides and Analogues
Medchemexpress LLC Clodronic acid disodium salt | 22560-50-5 | 100.50% | 250 MG
Clodronic acid disodium salt is a first-generation bisphosphonate that acts as an orally active osteoclastic bone resorption inhibitor. It can be utilized in cases of high bone turnover, Paget's disease, and osteolytic bone metastases. It induces rapid apoptosis in osteoclasts by preventing ADP translocation into mitochondria after internalization via resorption, which inhibits ATP production and leads to the release of cytochrome C into the cytoplasm.
- First-generation bisphosphonate
- Orally active osteoclastic bone resorption inhibitor
- Induces apoptosis in osteoclasts
Medchemexpress LLC Guanosine 5'-triphosphate (trisodium salt) | 36051-31-7 | 95.0% | 1 G
Guanosine 5'-triphosphate (5'-GTP) trisodium salt is a G protein signaling activator and a high-energy precursor in the biosynthesis of nucleotide units in DNA and RNA. It promotes myogenic cell differentiation by upregulating miRNA (miR133a, miR133b) and myogenic regulatory factor expression, and by inducing human myogenic precursor cells to release exosomes containing guanosine molecules. This product holds promise for research in biosynthesis and skeletal muscle regeneration.
- G protein signaling activator
- High-energy precursor in biosynthesis of nucleotide units in DNA and RNA
- Promotes myogenic cell differentiation
- Induces release of exosomes from human myogenic precursor cells
- Suitable for research in biosynthesis
- Suitable for research in skeletal muscle regeneration
Gold Biotechnology Inc ATP Disodium trihydrate
Adenosine-5 -triphosphate (ATP) is an important molecule in vivo for energy storage and metabolism and is often called the molecular unit of currency of intracellular energy transfer ATP is a coenzyme in multiple reactions as well as a substrate for multiple kinases where it helps to propagate a signal either inside or outside of the cell
Creative Biomart Elosulfase alfa, N-acetylgalactosamine-6-sulfatase
The product is a synthetic version of the enzyme N-acetylgalactosamine-6-sulfatase.
Medchemexpress LLC Adenosine 5'-triphosphate | 56-65-5 | 95.7% | 507.18 g/mol | C10H16N5O13P3 | 10 MG
Adenosine 5'-triphosphate (ATP) standard supplied as a 10 mg solid for analytical and research use. It is intended as a calibration and reference material for quantitation of ATP in biochemical assays, metabolic studies, and signaling research.
- Analytical reference standard for ATP quantitation.
- High purity: 95.7%.
- White to off-white solid suitable for dissolution in aqueous buffers.
- Useful for assay calibration, method development, and quality control.
- Includes CAS number 56-65-5 for clear substance identification.
Sigma Aldrich Fine Chemicals Biosciences 5-fluoro-2-deoxyuridine 5-5MG
5-fluoro-2-deoxyuridine 5-5MG
Sigma Aldrich Fine Chemicals Biosciences beta Nicotinamide adenine100MG
beta Nicotinamide adenine100MG
Medchemexpress LLC GTP-14564 | 34823-86-4 | 99.9% | 234.25 | 25 MG
GTP-14564 is a tyrosine kinase inhibitor that targets internal tandem duplication (ITD) and FLT3. It inhibits FLT3 ligand-dependent growth in Ba/F3 leukemia cells.
- Tyrosine kinase inhibitor
- Targets ITD and FLT3
- Inhibits FLT3 ligand-dependent growth in Ba/F3 leukemia cells
Medchemexpress LLC 2'-Deoxyuridine | 951-78-0 | 99.98% | 500 MG
2'-Deoxyuridine is a brain-penetrant pyrimidines nucleotide associated with nervous system diseases. It can increase chromosome breakage and decrease thymidylate synthetase activity. This product serves as a precursor in the synthesis of Edoxudine and is an analogue of 5-ethynyl-2'-deoxyuridine. It has shown promise in Alzheimer's disease (AD) research by reducing microglial activation and improving oxidative stress damage through modulation of glycolytic metabolism on Aβ25-35-induced brain injury.
- Associated with nervous system diseases.
- Increases chromosome breakage.
- Decreases thymidylate synthetase activity.
- Precursor in the synthesis of edoxudine.
- Analogue of 5-ethynyl-2'-deoxyuridine.
- Reduces microglial activation.
- Improves oxidative stress damage.
Sigma Aldrich Fine Chemicals Biosciences Adenosine 99100G
In the extracellular space ecto-5AE-nucleotidase (CD73) dephosphorylates adenosine triphosphate (ATP) to produce adenosine. Adenosine has four receptors namely A1R A2AR A2BR and A3R. Adenosine plays a key role in the osteogenic differentiation. A1R induces osteoclast differentiation and A2AR induces osteoblast differentiation.
Medchemexpress LLC Uridine | 58-96-8 | MFCD00006526 | 100.0% | 100 MG
Uridine (Standard) is an analytical standard used for research and analytical applications. It functions as a reference standard supplied assay in various experiments, including HPLC, GC, and MS. This compound is an endogenous metabolite and also a disease marker for Nervous System Disorder.
- Used as a reference standard supplied assay
- Commonly used in qualitative, quantitative, and methodological research experiments in HPLC, GC, and MS
- Molecular weight: 244.20
- Formula: C9H12N2O6
- Appearance: white to off-white solid
- Endogenous metabolite and disease marker for Nervous System Disorder