Nucleosides and Analogues
Apexbio Technology LLC ATP(Synonyms: Adenosine triphosphate, Adenosine 5'-triphosphate, Adenosine-5'-triphosphoric acid), 500mg, CAS: 56-65-5.
Adenosine triphosphate (ATP CAS 56-65-5) is a nucleoside triphosphate comprising adenine linked to ribose with three phosphate groups esterified sequentially ATP primarily functions as a universal energy carrier in cellular metabolism transferring phosphate groups to facilitate enzymatic reactions and drive biological activities Additionally ATP acts extracellularly as a neurotransmitter and signaling molecule binding purinergic receptors to modulate physiological responses such as neurotransmission vascular tone inflammation and immune cell function Due to its versatile biological roles ATP is extensively employed in biomedical research investigating metabolic pathways receptor signaling dynamics and cellular energetics
Apexbio Technology LLC Chloroquine diphosphate 50-63-5 10mM (in 1mL H2O)
Chloroquine diphosphate is an antimalarial agent and inhibitor of TLR7 and TLR9 commonly used in biomedical research to modulate autophagic processes On the cellular level chloroquine diphosphate promotes autophagy through cell cycle arrest at the G1 phase involving increased expression of p27 and p53 and decreased levels of CDK2 and cyclin D1 Additionally chloroquine diphosphate enhances sensitivity of cancer cells toward chemotherapy and radiotherapy treatments by elevating autophagy and apoptotic responses In vitro studies demonstrated dose-dependent activity with reported IC50 values typically ranging from approximately 15 to 40 M depending on cell types This compound is widely utilized as an autophagy modulator and therapeutic adjuvant in tumor cell models
Selleck Chemical LLC BRM/BRG1 ATP Inhibitor-1
BRM/BRG1 ATP Inhibitor-1 (Compound 14) is an orally active inhibitors of Brahma Homolog (BRM)/SMARCA2 (BRG1) with IC50s below 0 005 M
Apexbio Technology LLC 2'-O-Methyl-ATP(Synonyms: 2'-O-Methyladenosine 5'-triphosphate, 2'-OMe-ATP, ATP 2'-O-Methyl analog), 100ul (100 mM).
2 -O-Methyl-ATP is a chemically modified derivative of ATP in which the hydroxyl group at the ribose 2 position is replaced with a methyl group This ribose modification confers resistance to nuclease-mediated degradation thereby increasing its biological stability The modified nucleotide is commonly employed in biomedical research to investigate RNA structure-function relationships and RNA modification pathways and to study interactions influencing RNA polymerase specificity and catalytic activity Additionally 2 -O-Methyl-ATP serves as a tool in probe design for RNA interference experiments and aids in elucidating intracellular metabolic pathways involving nucleotide analogs
Medchemexpress LLC Uridine diphosphate glucuronic acid | 2616-64-0 | 98.0% | 580.29 g/mol | C15H22N2O18P2 | 10MG
Uridine diphosphate glucuronic acid (UDP-GlcA) is a sugar nucleotide cofactor used in biochemical and enzymatic research. It participates in glucuronidation and nucleotide sugar metabolism and serves as a substrate for glycosyltransferases and UDP-glucose dehydrogenase assays. The reagent is supplied for research use in biochemical assays and pathway studies.
- High purity (98.0%) for reliable assay performance.
- Molecular weight 580.29 g/mol and formula C15H22N2O18P2 for precise calculations.
- Available in small pack sizes including 10 mg for screening and method development.
- Suitable as a substrate in enzymatic and glycosylation studies.
- Provided with batch-specific COA and SDS for traceability.
Medchemexpress LLC Uridine diphosphate glucuronic acid | 2616-64-0 | 98.0% | 580.29 g·mol⁻¹ | C15H22N2O18P2 | 25MG
Uridine diphosphate glucuronic acid is a nucleotide sugar that functions as the glucuronic acid donor in glucuronidation and polysaccharide biosynthesis. Supplied as a research-grade biochemical with documented purity and analytical documentation, it is used in enzymology, metabolic assays, and in vitro glycosylation studies.
- Purity 98.0%.
- Molecular weight 580.29 g·mol⁻¹; formula C15H22N2O18P2.
- Used as a substrate or cofactor in glucuronyltransferase and enzymatic assays.
- Suitable for in vitro metabolism and glycosylation studies.
- Available in small research pack sizes including 25 mg.
- Supplied with a certificate of analysis and safety data sheet.
Medchemexpress LLC Nicotinamide riboside chloride | 23111-00-4 | MFCD27952781 | 99.9% | 290.70 g·mol⁻1 | C11H15ClN2O5 | 50G
Nicotinamide riboside chloride is an NAD+ precursor used in research to elevate cellular NAD+ levels and modulate sirtuin activity. Supplied as a powder, it is intended for biochemical and metabolic research applications including aging and neurodegeneration studies.
- High purity: 99.9%.
- Form: powder suitable for analytical and biochemical use.
- Molecular formula: C11H15ClN2O5; molecular weight: 290.70 g·mol⁻1.
- Application: used in NAD+ biosynthesis and sirtuin activation studies.
- Packaging: available as a 50 g research pack.
Selleck Chemical LLC Oritavancin Diphosphate-5MG
Oritavancin Diphosphate is an orally active glycopeptide antibiotic which is active against Gram-positive bacteria and also has antibacterial activity against multidrug-resistant Streptococcus pneumoniae
Apexbio Technology LLC 2-Amino-ATP(Synonyms: 2-NH2-ATP, 2-Aminoadenosine triphosphate, 2-Amino-adenosine-5'-triphosphate, 2-Amino-ATP (free acid)), 10ul (100 mM).
2-Amino-ATP is a modified nucleotide structurally related to ATP (adenosine triphosphate) featuring an amino substitution at the adenine ring s 2-position It acts as an ATP analog capable of competitively binding at the active sites of ATP-dependent enzymes potentially modulating their enzymatic activity and influencing downstream signaling pathways In research settings 2-Amino-ATP serves as a molecular tool to examine substrate specificity mechanistic aspects of ATP-binding enzymes (e g kinases and ATPases) and nucleotide-dependent receptor interactions facilitating studies of nucleotide signaling and cellular metabolism
Cambridge Isotope Laboratories Adenosine phosphoramidite (U-13C10 98% U-15N5 98%) CP 95% 10 mg
Adenosine phosphoramidite (U-13C10 98% U-15N5 98%) CP 95% 10 mg
