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Filtered Search Results
TARGETMOL CHEMICALS INC AMP-PCP disodium 5MG
Also available in 1 mg, 10 mg, 25 mg, 50 mg, 100 mg, 500 mg and bulk. Please contact Fisher for quotes. AMP-PCP disodium, an ATP analogue, binds to the N-terminal domain of Hsp90 with a Kd value of 3.8 uM, facilitating the formation of an active Hsp90 homodimer. Purity 100%
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eMolecules 129832-03-7 | PHYTIC ACID DIPOTASSIUM | AstaTech | MFCD00133773 | 736.209 | C6H16K2O24P6 | 98.000 | [K+].[K+].OP(O)(=O)O[C@H]1[C@H](OP(O)(O)=O)[C@H](OP(O)(O)=O)[C@H](OP([O-])([O-])=O)[C@@H](OP(O)(O)=O)[C@@H]1OP(O)(O)=O | 100g | 410713853
PHYTIC ACID DIPOTASSIUM | AstaTech | 129832-03-7 | MFCD00133773 | 736.209 | C6H16K2O24P6 | 98.000 | [K+].[K+].OP(O)(=O)O[C@H]1[C@H](OP(O)(O)=O)[C@H](OP(O)(O)=O)[C@H](OP([O-])([O-])=O)[C@@H](OP(O)(O)=O)[C@@H]1OP(O)(O)=O | 100g | 410713853
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Medchemexpress LLC K-Ras ligand-Linker Conjugate 4 | 2378261-83-5 | 98.8% | 50 MG
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K-Ras ligand-Linker Conjugate 4 integrates a ligand for K-Ras recruiting moiety and a PROTAC linker, which recruits E3 ligases (VHL, CRBN, MDM2, IAP). It is used in the synthesis of a potent PROTAC K-Ras degrader that demonstrates ≥70% degradation efficacy in SW1573 cells. PROTACs utilize the intracellular ubiquitin-proteasome system for selective degradation of target proteins by connecting a ligand for an E3 ubiquitin ligase with a ligand for the target protein.
- Incorporates a ligand for K-Ras recruiting moiety.
- Features a PROTAC linker to recruit E3 ligases.
- Used in the synthesis of potent protein degraders.
- Facilitates selective degradation of target proteins.
- Leverages the ubiquitin-proteasome system.
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AdipoGen BQC
Chemical. CAS 207124-63-8. Formula C20H10K2N2O4 . 3H2O. MW 474.55. 2,2´-Biquinoline-4,4´-dicarboxylic acid dipotassium salt BQC is a water soluble biquinoline-based ligand. The oxidation of alcohols to the corresponding aldehydes and ketones, which can be performed by a variety of methods, remains one of the most important reactions in organic synthesis. BOC is used in the aerobic oxidation of alcohols primary, secondary and benzylic in the presence of palladium catalysts. The catalytic system composed of CuCl2 and BQC was found to be highly efficient for the selective oxidation of secondary benzylic, allylic and propargylic alcohols to the corresponding ketones, with aqueous t-butyl hydroperoxide under phase-transfer catalysis conditions. The catalytic system is stable and can be recycled and reused several times without loss of activity.
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Medchemexpress LLC Dipotassium hydrogen phosphate | 7758-11-4 | MFCD00011383 | 100.0% | 174.176 g/mol | K2HPO4 | 500 G
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Dipotassium hydrogen phosphate (K2HPO4, CAS 7758-11-4) is an anhydrous dibasic potassium phosphate salt used as a buffering agent, pH adjuster, and phosphate source in laboratory and pharmaceutical applications. It typically appears as a white crystalline powder with high purity and solubility in water, making it suitable for biochemical assays, media preparation, and formulation work requiring stable alkaline buffer capacity.
- High purity (99.95%) suitable for analytical and formulation use.
- Functions as a buffering agent and pH adjuster in aqueous systems.
- Provides a soluble source of phosphate for media and reagent preparation.
- Available in lab-scale pack sizes up to 500 g for routine use.
- Stable, white crystalline powder with good water solubility.
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Medchemexpress LLC GLUCOSE-6-PHOSPHATE 5UG
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5000195531 GLUCOSE-6-PHOSPHATE 5UG
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Medchemexpress LLC K-Ras ligand-Linker Conjugate 4 | 2378261-83-5 | 98.8% | 1 ML
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K-Ras ligand-Linker Conjugate 4 incorporates a ligand for the K-Ras recruiting moiety and a PROTAC linker, designed to recruit E3 ligases such as VHL, CRBN, MDM2, and IAP. This conjugate is utilized in the synthesis of potent PROTAC K-Ras Degrader-1, which has demonstrated ≥70% degradation efficacy in SW1573 cells. PROTACs function by connecting two different ligands, one for an E3 ubiquitin ligase and another for the target protein, enabling the selective degradation of target proteins via the intracellular ubiquitin-proteasome system.
- Incorporates a ligand for a K-Ras recruiting moiety
- Includes a PROTAC linker to recruit E3 ligases (VHL, CRBN, MDM2, IAP)
- Used in the synthesis of a potent PROTAC K-Ras degrader
- Demonstrates high degradation efficacy in SW1573 cells
- Utilizes the intracellular ubiquitin-proteasome system for selective protein degradation
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Medchemexpress LLC Baricitinib phosphate | 1187595-84-1 | C16H20N7O6PS | 500 MG
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Baricitinib phosphate is a selective, orally bioavailable inhibitor targeting JAK1 and JAK2 pathways. It demonstrates potent inhibition of JAK signaling and function in various cellular assays, making it suitable for research applications.
- Selective JAK1/JAK2 inhibitor with high potency
- Inhibits IL-6-stimulated STAT3 phosphorylation and MCP-1 production in PBMCs
- Inhibits pSTAT3 stimulated by IL-23 in isolated naive T-cells
- Prevents IL-17 and IL-22 production by Th17 cells
- Demonstrates anti-inflammatory effects in vivo, reducing hind paw swelling and immune cell infiltration
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Selleck Chemical LLC Phytic acid dipotassium salt S3326-25mg
Phytic acid dipotassium salt (Phytic acid potassium IP6 (PS)) an endogenous metabolite in rice grain extract and digest inhibits -secretase 1 (BACE1) with IC50 of approximately 0 25 M
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Medchemexpress LLC Glucose 6 Phosphate Dehydrogenase Antibody (YA411) | affinity purified | 59 kDa | 100 UL
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Glucose 6 Phosphate Dehydrogenase Antibody (YA411) is a rabbit-derived, non-conjugated IgG monoclonal antibody designed to target Glucose 6 Phosphate Dehydrogenase (G6PD). This product is suitable for various research applications, including Western Blot (WB), Immunohistochemistry-Paraffin (IHC-P), and Immunoprecipitation (IP), and has demonstrated reactivity in both human and rat samples.
- Rabbit-derived monoclonal antibody
- Non-conjugated IgG format
- Targets Glucose 6 Phosphate Dehydrogenase (G6PD)
- Applications include Western Blot (WB), Immunohistochemistry-Paraffin (IHC-P), and Immunoprecipitation (IP)
- Reactive with human and rat samples
- Affinity purified
- Supplied as a liquid formulation
- Store at -20°C for 1 year, avoid freeze/thaw cycles
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Medchemexpress LLC Retagliptin phosphate | 1256756-88-3 | 99.7% | 562.36 | 10 MG
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Retagliptin phosphate (SP2086 phosphate) is a selective, competitive, and orally active dipeptidyl peptidase-4 (DPP-4) inhibitor. It can be used for type 2 diabetes mellitus (T2DM) research, inhibiting the degradation of GLP-1 and amplifying the incretin effect.
- Selective, competitive, and orally active dipeptidyl peptidase-4 (DPP-4) inhibitor.
- Available in solid and solution forms.
- For research use only.
- Can be used for type 2 diabetes mellitus (T2DM) research.
- Inhibits the degradation of GLP-1, amplifying the incretin effect.
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Medchemexpress LLC EC-17 disodium salt | 910661-33-5 | 96.3% | 916.82 | 25 MG
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EC-17 disodium salt is a folate receptor alpha (FRα) targeting contrast agent that exhibits fluorescent properties within the visible light spectrum. Its maximum excitation and emission wavelengths are 490 nm and 520 nm, respectively. It is intended for research use only.
- Folate receptor alpha (FRα) targeting contrast agent
- Fluorescent properties in the visible light spectrum
- Maximum excitation wavelength: 490 nm
- Maximum emission wavelength: 520 nm
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Medchemexpress LLC BRD4 ligand-linker conjugate 1 TFA | 00-00-0 | 98.7% | C30H31ClF3N7O2 | 10MG
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BRD4 ligand-Linker Conjugate 1 TFA is a target protein ligand-linker conjugate supplied as the trifluoroacetic acid (TFA) salt for use in the synthesis of PROTACs. The material is provided in pre-weighed laboratory quantities and is characterized for purity and identity.
- Designed for assembly of PROTAC molecules.
- Provided as the TFA salt for stability and handling.
- High purity (98.7%) suitable for synthetic applications.
- Characterized by molecular weight 614.06 and formula C30H31ClF3N7O2.
- Supplied in multiple pre-weighed pack sizes for medicinal chemistry use.
- Structural and analytical data available on the product page.
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Medchemexpress LLC BRD4 LIGAND-LINKER C 50 mg
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BRD4 LIGAND-LINKER C 50MG
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Medchemexpress LLC Potassium phosphate, dibasic | 7758-11-4 | MFCD00011383 | 100.0% | 174.17 g/mol | K2HPO4 | 250 G
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Dipotassium hydrogen phosphate (potassium phosphate dibasic, K2HPO4) is an anhydrous, white crystalline salt used as a buffering agent, pH adjuster, and pharmaceutical excipient. It offers reliable buffering capacity in aqueous formulations and is suitable for laboratory and formulation applications where high purity is required.
- Provides stable buffering capacity in aqueous systems.
- High purity suitable for analytical and formulation use.
- Soluble in water; may require sonication for complete dissolution.
- Available in multiple laboratory-scale pack sizes.
- Useful for pH control and excipient formulations.
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