Sugar acids and derivatives
Medchemexpress LLC Interferon alpha/beta receptor 1 Antibody (YA3833) | Predicted band size: 64 kDa; Observed band size: 110-130 kDa | 50 UL
The Interferon alpha/beta receptor 1 Antibody (YA3833) is a mouse-derived, non-conjugated IgG1 monoclonal antibody that targets Interferon alpha/beta receptor 1. This antibody is intended for research use only. Interferon alpha/beta receptor 1 (IFNAR1), in conjunction with IFNAR2, forms the heterodimeric receptor crucial for type I interferon signaling. Binding of type I interferons initiates the JAK-STAT signaling cascade, which leads to the transcriptional regulation of interferon-regulated genes that mediate the interferon response.
- Host: Mouse
- Clonality: Monoclonal antibody
- Species reactivity: Human, mouse
- Conjugation: Non-conjugated
- Isotype: IgG1
- Appearance: Liquid
- Formulation: Supplied in PBS with 0.05% sodium azide
- Purity: Affinity purified
- Storage: Stored at -20°C for 1 year. Avoid repeated freeze/thaw cycles.
- Applications: WB, IHC-P, FC, ELISA
Medchemexpress LLC (D-Trp6)-LHRH free acid | 129418-54-8 | 99.7% | 1312.43 | 10 MG
(D-Trp6)-LHRH free acid is a luteinizing hormone-releasing hormone (LHRH) agonist. In vitro, (D-Trp6)-LHRH free acid (10 μM; 24 h or 6 days) reduces the proliferation of human epithelial ovarian cancer cell lines EFO-21 and EFO-27.
- Acts as a luteinizing hormone-releasing hormone (LHRH) agonist
- Reduces proliferation of human epithelial ovarian cancer cell lines EFO-21 and EFO-27
- High purity of 99.67%
- White to off-white solid appearance
Medchemexpress LLC PROTAC BET Degrader-10 | 1957234-97-7 | 99.4% | 783.29 | 1 ML
PROTAC BET Degrader-10 (dBET37) is a potent BET protein BRD4 degrader, connected by ligands for Cereblon and BRD4, with a DC50 of 49 nM. This compound utilizes PROTAC technology, containing two different ligands connected by a linker; one for an E3 ubiquitin ligase and the other for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- Potent BET protein BRD4 degrader
- Connected by ligands for Cereblon and BRD4
- DC50 of 49 nM
- Exploits the intracellular ubiquitin-proteasome system to selectively degrade target proteins
- For research use only
- Components include a BRD4(BD1BD2) ligand, a Cereblon ligand, and a linker
- Appearance is a solid
- Color is off-white to light yellow
Medchemexpress LLC 4-Methylumbelliferyl-α-d-mannoside | 28541-83-5 | 99.3% | 338.31 | 5 MG
4-Methylumbelliferyl-α-d-mannoside is a fluorescent substrate for α-D-mannosidase. For research use only.
- Fluorescent substrate for α-D-mannosidase.
- For research use only.
Medchemexpress LLC Integrin alpha X bet 50ug
Integrin -X/ -2 is a receptor for fibrinogen that recognizes GPR sequences It plays a key role in inflammatory responses particularly in monocyte adhesion and chemotaxis Integrin alpha X beta 2 Protein Human (HEK293 Flag His) is a recombinant protein dimer complex containing human-derived Integrin alpha X beta 2 protein expressed by HEK293 with C-His C-Flag labeled tag
Medchemexpress LLC BET bromodomain inhibitor | 1505453-59-7 | MFCD28144506 | 99.5% | 445.90 | C24H20ClN5O2 | 25 MG
BET bromodomain inhibitor is a research-grade small-molecule inhibitor of BET family bromodomain proteins used in preclinical and in vitro studies to probe transcriptional regulation, cell proliferation, and apoptosis. The compound has molecular formula C24H20ClN5O2 and a molecular weight of 445.90, and is supplied as a high-purity solid for laboratory use.
- Research use only; not for human or clinical use.
- Potent BET family bromodomain inhibition for mechanistic and cellular assays.
- High purity suitable for analytical and biological studies.
- Available in small solid quantities for laboratory experiments.
Medchemexpress LLC Integrin alpha 6 bet 5ug
Integrin alpha 6 beta 1 Protein Human (HEK293 Flag-His) is the recombinant human-derived Integrin alpha 6 beta 1 protein expressed by HEK293 with C-His C-Flag labeled tag has molecular weight of 110 130 kDa respectively
Medchemexpress LLC Guanylyl Cyclase beta 1 Antibody (YA2147) | 50 UL
The Guanylyl Cyclase beta 1 Antibody (YA2147) is a rabbit-derived, non-conjugated IgG monoclonal antibody specifically designed to target Guanylyl Cyclase beta 1. This antibody mediates responses to nitric oxide (NO) by catalyzing the biosynthesis of the signaling molecule cGMP, making it suitable for various research applications.
- Rabbit-derived recombinant monoclonal antibody
- Non-conjugated IgG isotype
- Targets Guanylyl Cyclase beta 1
- Reacts with human, mouse, and rat species
- Suitable for Western Blot (1:500-1:1000) and Immunohistochemistry-Paraffin (1:50-1:100) applications
- Stored at -20°C for one year
- Avoid repeated freeze/thaw cycles
- Formulated with 50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide, and 0.05% BSA
Medchemexpress LLC [D-Trp34]-Neuropeptide Y | 153549-84-9 | 99.7% | 4311.72 | 10 MG
[D-Trp34]-Neuropeptide Y is a potent and selective neuropeptide Y (NPY) Y5 receptor agonist. It is significantly less potent at the NPY Y1, Y2, Y4, and y6 receptors. This product markedly increases food intake in rats.
- Potent and selective neuropeptide Y (NPY) Y5 receptor agonist.
- Markedly increases food intake in rats.
Medchemexpress LLC 4-Methylumbelliferyl-β-D-glucuronide hydrate | 881005-91-0 | 99.9% | 1 ML
4-Methylumbelliferyl-β-D-glucuronide hydrate is a fluorogenic substrate with an excitation wavelength of 362 nm and an emission wavelength of 445 nm. This compound is used in various enzymatic reactions and has applications in detecting β-glucuronidase activity and quantifying *Escherichia coli*.
- Fluorogenic substrate with λex=362 nm and λem=445 nm
- Detects activity of β-glucuronidase
- Quantifies *Escherichia coli*
- Releases 4-methylumbelliferone in enzymatic reactions
- Suitable for kinase assays to measure GLUase activity
Medchemexpress LLC D-Glucuronic acid lactone | 32449-92-6 | MFCD00135622 | 98.0% | 176.12 | 5 G
D-Glucuronic acid lactone is an endogenous metabolite and a glucuronic acid derivative. It serves as a starting reagent for the synthesis of 2,3,4-tris (tert-butyldimethylsilyl) glucuronic acid trichloroethyl ester, which is used to prepare 1-O-acyl glucuronic acids, synthesize optically active glucuronic acids, and produce long-chain alkyl glucuronides. It also shows potential for use in studies of reversible cerebral vasoconstriction syndrome (RCVS).
- Endogenous metabolite and glucuronic acid derivative
- Starting reagent for the synthesis of specific glucuronic acid esters
- Prepares 1-O-acyl glucuronic acids
- Synthesizes optically active glucuronic acids
- Produces long-chain alkyl glucuronides
- Potential use in studies of reversible cerebral vasoconstriction syndrome (RCVS)
Medchemexpress LLC D-Glucuronic acid (Standard) | 6556-12-3 | 100 MG
D-Glucuronic acid (Standard) is an analytical standard intended for research and analytical applications. It is a significant component of numerous anti-inflammatory proteoglycans, contributing to embryonic development and inhibiting cell aggregation. When metabolized into ethyl glucuronide, it activates Toll-like receptor 4 (TLR4), which is associated with pain. Furthermore, D-Glucuronic acid and its derivative, glucurono-lactone, are known as liver detoxifiers and its derivatives also exhibit anti-tumor activity.
- Analytical standard for assays
- Intended for research and analytical use
- Utilized in HPLC, GC, and MS research experiments
- Major component of anti-inflammatory proteoglycans
- Promotes embryonic development
- Inhibits cell aggregation
- Acts as a liver detoxifier
- Derivatives possess anti-tumor activity
- Solid, white to off-white appearance
- Purity of 99.93%
Medchemexpress LLC Heparin sodium salt (MW 15kDa) | 9041-08-1 | 15000 (Average) | 5 G
Heparin sodium salt (MW 15kDa) is a polymer of Heparin with a molecular weight of 15kDa. It functions as an anticoagulant by reversibly binding to antithrombin III (ATIII), which significantly increases the rate at which ATIII inactivates coagulation enzymes thrombin factor IIa and factor Xa. This product has shown angiogenic response in late Chorioallantoic Membrane (CAM) assay. It is suitable for laboratory centrifugation and storage.
- Acts as an anticoagulant
- Binds reversibly to antithrombin III (ATIII)
- Accelerates inactivation of coagulation enzymes
- Used in various biological activities targeting thrombin and factor Xa
- Shows angiogenic response in CAM assay
Medchemexpress LLC β-D-glucopyranuronic acid methyl ester, 1,2,3,4-tetrakis(2-methylpropanoate) | 150607-94-6 | 98.1% | 488.53 g/mol | C23H36O11 | 10 MG
β-D-Glucopyranuronic acid methyl ester, 1,2,3,4-tetrakis(2-methylpropanoate) is a chemically synthesized methyl ester derivative of D-glucopyranuronic acid supplied as a high-purity research reagent for glycobiology and carbohydrate chemistry applications. It is intended for analytical use, synthesis work, and assay development in laboratory settings.
- High purity (98.1%) suitable for analytical applications.
- Chemical formula C23H36O11; molecular weight 488.53 g/mol.
- Identified by CAS number 150607-94-6 for unambiguous reference.
- Available in small package sizes, including 10 mg, for research use.
- Useful as a building block or standard in carbohydrate chemistry and glycobiology studies.
AdipoGen 3-Oxo-C9-L-HSL
Chemical. CAS 441350-70-5. Formula C13H21NO4. MW 255.31. N-3-Oxononanoyl-L-homoserine lactone is a small diffusible signaling molecule and is a member of N-acyl-homoserine lactone family. N-acylhomoserine lactones AHL are involved in quorum sensing, controlling gene expression and cellular metabolism. The diverse applications of this kind of molecule include regulation of virulence in general, infection prevention, and formation of biofilms.