Sugar acids and derivatives
![Apexbio Technology LLC heparin cofactor II precursor fragment [Homo sapiens] 5mg](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000097081.png-250.jpg)
Apexbio Technology LLC heparin cofactor II precursor fragment [Homo sapiens] 5mg
Heparin cofactor II precursor fragment is a thrombin inhibitor peptide targeting human thrombin (factor IIa) It is designed to inhibit thrombin activity thereby modulating blood coagulation pathways Heparin cofactor II precursor fragment exerts its biological activity primarily through serine protease inhibition facilitated in the presence of heparin or dermatan sulfate Based on these pharmacological properties heparin cofactor II precursor fragment holds research potential in investigating thrombin inhibition mechanisms blood coagulation pathways and conditions associated with altered coagulation such as heparin cofactor II deficiency and hypercoagulability disorders
Medchemexpress LLC IFN-beta Rhesus Mac 2ug
IFN-beta Protein is an immunomodulatory cytokine of the type 1 interferon family IFN-beta Protein reduces joint inflammation by inhibiting the RANKL-c-Fos signaling pathway IFN-beta Protein regulates mitochondrial fission through STAT5 PGAM5 and Drp1 to rescue neurodegeneration IFN-beta Protein Rhesus Macaque (HEK293 Fc) is the recombinant Rhesus Macaque-derived IFN-beta protein expressed by HEK293 with C-mFc labeled tag
AdipoGen 3OH-C10-L-HSL
Chemical. CAS 192883-12-8. Formula C14H25NO4. MW 271.35. Synthetic. N-3-hydroxydecanoyl-L-homoserine lactone is a small diffusible signaling molecule secreted by various bacteria and involved in quorum sensing, thereby controlling gene expression and affecting cellular metabolism. This lactone is produced via lactonolysis from 3-oxodecanoyl-homoserine lactone, altering quorum sensing or contributing to quorum quenching. The applications of this molecule include regulation of virulence and exoproteases.
Medchemexpress LLC Integrin alpha V bet 50ug | 50ug
Integrin alpha V beta 3 (ITGAV ITGB3) functions as a receptor for CD40LG enhancing Lilrb4a inhibitory effects on mast cell activation It suppresses marginal zone B cell antibody production through Lilrb4a interaction ITGAV ITGB3 forming a heterodimer with ITGAV interacts with ligands such as RAB25 CIB1 FBLN5 and more It also forms a complex with PTPRZ1 and PTN stimulating endothelial cell migration Integrin alpha V beta 6 Protein Mouse (HEK293 His) is a recombinant protein dimer complex containing mouse-derived Integrin alpha V beta 6 protein expressed by HEK293 with C-His labeled tag Integrin alpha V beta 6 Protein Mouse (HEK293 His) has molecular weight of 90-140 kDa
Medchemexpress LLC Integrin alpha 8 bet 10ug
Integrin -8/ -1 coordinates the recruitment of mesenchymal cells during renal organogenesis and recognizes RGD sequences in ligands such as TNC FN1 SPP1 TGFB1 TGFB3 and VTN It plays a role in multiple cellular interactions critical for organogenesis including NPNT as a functional ligand in nephrogenesis Integrin alpha 8 beta 1 Protein Human (HEK293 His) is a recombinant protein dimer complex containing human-derived Integrin alpha 8 beta 1 protein expressed by HEK293 with C-His labeled tag Integrin alpha 8 beta 1 Protein Human (HEK293 His) has molecular weight of 120-140 kDa 100-120 kDa respectively
Medchemexpress LLC 2H-1-benzopyran-2-one, 7-(beta-D-glucopyranosyloxy)-4-methyl- | 18997-57-4 | MFCD00063694 | 99.9% | 338.31 g/mol | C16H18O8 | 10MM 1ML
4-Methylumbelliferyl β-D-glucopyranoside is a coumarin-based fluorogenic substrate used to measure β-glucosidase and related enzyme activities. Enzymatic hydrolysis releases the fluorescent 4-methylumbelliferone (4-MU), which emits near 445-454 nm; excitation is pH-dependent. The product is supplied as a 10 mM solution in DMSO (1 mL) and is suitable for fluorescence-based biochemical assays.
Medchemexpress LLC 4-Methylumbelliferyl 100mg | 18323-58-5 | 440.61 g·mol^-1 | C28H40O4 | 100 MG
4-Methylumbelliferyl oleate is a fluorogenic substrate for acid and alkaline lipases. Upon enzymatic hydrolysis, it liberates 4-methylumbelliferone (4-MU), enabling sensitive fluorometric detection and kinetic assays (Ex/Em 320/450 nm).
- Provides a fluorogenic readout upon lipase-catalyzed hydrolysis.
- Releases 4-methylumbelliferone with Ex/Em 320/450 nm for sensitive detection.
- High chemical purity suitable for enzymatic assays.
- Stable when stored at -20°C and protected from light; solvent stability guidelines available.
- Available in multiple pack sizes to support assay development and scale-up.
Medchemexpress LLC Integrin alpha X bet 100ug
Integrin -X/ -2 is a receptor for fibrinogen that recognizes GPR sequences It plays a key role in inflammatory responses particularly in monocyte adhesion and chemotaxis Integrin alpha X beta 2 Protein Human (HEK293 His) is a recombinant protein dimer complex containing human-derived Integrin alpha X beta 2 protein expressed by HEK293 with C-His labeled tag Integrin alpha X beta 2 Protein Human (HEK293 His) has molecular weight of 130-150 kDa (ITGAX) 85-96 kDa (ITGB2) respectively
Apexbio Technology LLC Beta-Lapachone 4707-32-8 10mg
Beta-Lapachone (CAS 4707-32-8) is a small molecule inhibitor of DNA topoisomerase I In DNA unwinding assays beta-Lapachone suppresses topoisomerase I-mediated DNA relaxation at concentrations as low as 1 M without inhibiting topoisomerase II or inducing topoisomerase I-dependent DNA cleavage It exhibits broad cytotoxicity against human cancer cell lines such as AD2780s HT-29 DLD G480 and MCF-7 with IC50 values ranging from 2 to 5 M The compound induces cell death through cytochrome c release triggering both apoptosis and necrosis and affects cell cycle progression causing S-phase and G2/M arrest in different carcinoma cell models Beta-Lapachone is widely utilized in studies investigating topoisomerase I inhibition cancer cell cytotoxicity and cell cycle regulation
eMolecules 5-Methoxy-1-methyl-1H-indole-3-carbaldehyde | 39974-94-2 | MFCD01578324 | 5g
WuXi ChemSupply | 5-Methoxy-1-methyl-1H-indole-3-carbaldehyde | 5g | 599164252 | LN00140967 | 95.000 | 39974-94-2 | MFCD01578324 | 189.214 | C11H11NO2
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AdipoGen 3-OH-C5-DL-HSL
Chemical. CAS 148433-24-3. Formula C9H15NO4. MW 201.22. 3-Hydroxy-pentanoyl-DL-homoserine lactone is a small diffusible signaling molecule and is a member of N-acyl-homoserine lactone family. N-acylhomoserine lactones AHL are involved in quorum sensing, controlling gene expression, and cellular metabolism. The diverse applications of this kind of molecule include regulation of virulence in general, infection prevention, and formation of biofilms.
Medchemexpress LLC [D-Ala2]-GIP (human) | 444073-04-5 | 98.97% | 4983.60 | 25 MG
[D-Ala2]-GIP (human) is a GIP receptor agonist with an EC50 of 630 pM. It improves glucose tolerance and demonstrates neuroprotective activity in an MPTP-induced Parkinson's disease model. Additionally, it enhances cognitive function and hippocampal synaptic plasticity in obese diabetic rats. This product is suitable for research related to type 2 diabetes, Parkinson's disease, and similar conditions.
- Acts as a GIP receptor agonist with an EC50 of 630 pM
- Improves glucose tolerance by stimulating insulin release
- Demonstrates neuroprotective activity in MPTP-induced Parkinson's disease models
- Enhances cognitive function and hippocampal synaptic plasticity in obese diabetic rats
- Attenuates the behavioral phenotype of Parkinson's disease
- Reverses decline in motor ability and reduces muscle stiffness
- Inhibits the increase of MDA levels in the brain
Medchemexpress LLC 4-Methylumbelliferyl-2-acetamido-2-deoxy-β-D-Glucopyranoside | 37067-30-4 | 99.95% | 379.36 | 250 MG
4-Methylumbelliferyl-2-acetamido-2-deoxy-β-D-Glucopyranoside is a fluorogenic substrate for N-acetyl-β-D-glucosaminidase. The enzyme functionality is assessed by its ability to remove terminal β-glycosidically bound N-acetylglucosamine and N-acetylgalactosamine residues from the compound.
- Fluorogenic substrate for N-acetyl-β-D-glucosaminidase
- Assesses enzyme functionality by removing terminal β-glycosidically bound N-acetylglucosamine and N-acetylgalactosamine residues
- White to off-white solid appearance
- Classified as a fluorescent dye and enzyme labeling agent
Medchemexpress LLC Thiazolo[4,5-d]pyrimidine-2(3H)-thione, 7-chloro-3-(2,4-dimethoxyphenyl)-5-methyl- | 2459916-56-2 | 98.5% | 353.85 | 25 MG
CDK1/Cyc B-IN-1 (Compound 5) is a selective CDK1/Cyc B complex inhibitor with an IC50 of 97 nM. It induces apoptosis and G2/M cell cycle arrest, and exhibits broad-spectrum cytotoxic action against various cancer cell lines.
- Selective inhibitor of the CDK1/Cyc B complex.
- Induces apoptosis and G2/M cell cycle arrest.
- Exhibits broad-spectrum cytotoxic action against cancer cell lines.
- Cytotoxic activity against HCT-116 cells and WI-38 cells.
Medchemexpress LLC 4-Methylumbelliferyl β-D-galactopyranoside | 6160-78-7 | MFCD00036773 | 99.1% | 338.31 | 250 MG
4-Methylumbelliferyl β-D-galactopyranoside is a fluorescent substrate for β-galactosidase. When cleaved, it produces a water-soluble blue fluorescent coumarin fluorophore that can be detected using a fluoroenzymeter or fluorometer.
- Fluorescent substrate for β-galactosidase
- Produces a blue fluorescent coumarin fluorophore upon cleavage
- Fluorophore detectable by fluoroenzymeter or fluorometer
- Purity: 99.06%
- Molecular weight: 338.31
- Chemical formula: C16H18O8
- Appearance: Solid, white to off-white
- Emission (Em): 480; Excitation (Ex): 390
- Solubility: 41.67 mg/mL in DMSO
- Shipping: Room temperature
- Storage: -20°C (solid); -80°C (6 months) or -20°C (1 month) in solvent, protect from light