Drug Standards
Sigma Aldrich Fine Chemicals Biosciences Formoterol for impurity I identification European Pharmacopoeia (EP) Reference Standard | 43229-80-7 |
Formoterol for impurity I identification European Pharmacopoeia (EP) Reference Standard | Mol Wt: 402.44 | 43229-80-7 |
Medchemexpress LLC Rivaroxaban impurity 250mg
Rivaroxaban impurity 1 is an impurity of Rivaroxaban (HY-50903)
Medchemexpress LLC 11-oxo-mogroside V | 126105-11-1 | MFCD16038053 | 99.9% | 1285.42 | C60H100O29 | 10 MG
11-oxo-mogroside V is a plant-derived triterpenoid glycoside supplied as a white to off-white solid for research use. It exhibits antioxidant activity and is used in biochemical and pharmacological studies investigating reactive oxygen species and related cellular assays. Solubilize in DMSO for in vitro experiments and follow recommended storage conditions.
Cayman Chemical DIclofenac methyl ester 50mg
A prodrug form of diclofenac; more soluble than diclofenac acid in isopropylmyristate; does not permeate human epidermal membranes in vitro
Medchemexpress LLC Salbutamol | 18559-94-9 | MFCD00148978 | 99.5% | 1 ML
Salbutamol (Albuterol) is an orally active, short-acting β2-adrenergic receptor agonist, primarily used in research for bronchospasm in conditions like asthma and COPD. Studies indicate its role in gastric cancer tumorigenesis via the β2-AR/ERK/EMT pathway and its protective effect against Streptozotocin-induced skeletal muscle atrophy in diabetic rats.
- Orally active short-acting β2-adrenergic receptor agonist.
- Used in research for bronchospasm related to asthma and chronic obstructive pulmonary disease.
- Induces EMT, migration, and invasion in gastric cancer cells in vitro.
- Increases tumor growth in nude mice with gastric cancer in vivo.
- Protects against Streptozotocin-induced skeletal muscle atrophy in diabetic rats by enhancing muscle strength, coordination, and antioxidant levels, reducing inflammation and oxidative stress, and improving muscle cellular architecture.
Medchemexpress LLC Methylprednisolone succinate | 2921-57-5 | 99.7% | 1 ML
Methylprednisolone succinate is a prodrug of Methylprednisolone and a glucocorticoid with immunosuppressant and anti-inflammatory activity. It functions by binding to cytosolic glucocorticoid receptors, modulating target gene transcription, and suppressing proinflammatory cytokine production and immune cell activation. This compound is researched for various conditions, including intracranial hemorrhage, rheumatoid arthritis, multiple sclerosis, and inflammatory states.
- Prodrug of Methylprednisolone.
- Possesses immunosuppressant and anti-inflammatory properties.
- Modulates target gene transcription.
- Suppresses proinflammatory cytokine production.
- Attenuates TLR4/NF-κB signaling.
- Researched for intracranial hemorrhage, rheumatoid arthritis, and multiple sclerosis.
- Available as a 10 mM solution in DMSO.
Medchemexpress LLC Desmethyl celecoxib | 170569-87-6 | MFCD03453540 | 99.4% | 367.35 | C16H12F3N3O2S | 1 ML
Desmethyl celecoxib is a selective cyclooxygenase-2 (COX-2) inhibitor and an analog of celecoxib, used as a research reagent for COX-2 modulation and inflammation studies. Offered as a 10 mM solution in DMSO (1 mL) or as solid powder formats.
- Selective COX-2 inhibitor (IC50 = 32 nM).
- Supplied as 10 mM solution in DMSO, 1 mL.
- High reported purity (99.42%).
- Molecular weight 367.35 g/mol.
- Appearance: white to off-white solid; solution ready to use.
- Recommended storage: powder -20°C for long term; in solvent -80°C for best stability.
![eMolecules Ambeed / rel-((1R8S9s)-Bicyclo[6.1.0]non-4-yn-9-yl)methyl (4-nitrophenyl) carbonate / 25mg / 682931751 / A756306 / / 1263166-91-1 / [null] / 315.325 / C17H17NO5](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502460196.PNG-250.jpg)
eMolecules Ambeed / rel-((1R8S9s)-Bicyclo[6.1.0]non-4-yn-9-yl)methyl (4-nitrophenyl) carbonate / 25mg / 682931751 / A756306 / / 1263166-91-1 / [null] / 315.325 / C17H17NO5
Ambeed / rel-((1R8S9s)-Bicyclo[6.1.0]non-4-yn-9-yl)methyl (4-nitrophenyl) carbonate / 25mg / 682931751 / A756306 / / 1263166-91-1 / [null] / 315.325 / C17H17NO5
Selleck Chemical LLC Rociletinib (CO-1686) 10mg 1374640-70-6 AVL-301
Rociletinib (CO-1686, AVL-301) is an irreversible, mutant-selective EGFR inhibitor with Ki of 21.5 nM and 303.3 nM for EGFRL858R/T790M and EGFRWT in cell-free assays, respectively. Phase 2. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
Sigma Aldrich Fine Chemicals Biosciences Glycopyrrolate Related Compound B United States Pharmacopeia (USP) Reference Standard | 13118-11-1 | 50MG
Glycopyrrolate Related Compound B United States Pharmacopeia (USP) Reference Standard | Mol Wt: 303.4 | 13118-11-1 | 50MG
Sigma Aldrich Fine Chemicals Biosciences Clozapine | 5786-21-0 | MFCD00153785 | 1G
Clozapine | Mol Wt: 326.82 | 5786-21-0 | MFCD00153785 | 1G
Medchemexpress LLC Neratinib | 698387-09-6 | MFCD09752958 | 99.9% | 557.0 g/mol | 1 ML
Neratinib (HKI-272) is an orally available, irreversible, highly selective HER2 and EGFR inhibitor with IC50s of 59 nM and 92 nM, respectively.
- Inhibits proliferation of cell lines with high HER-2 levels.
- Less active in cell lines not expressing HER-2 or EGFR.
- Arrests cell cycle at G1-S phase.
- Causes inhibition of MAPK and Akt phosphorylation, down-regulation of cyclin D1 levels, and induction of p27.
- Shows anticancer activities against cancer cells expressing high levels of HER-2 or EGFR in vivo.
- Reduces tumor growth in a dose-dependent manner in xenografts.
- Inhibits phosphorylation of HER-2 in xenografts.
Medchemexpress LLC Palbociclib impurity 20 | 1774898-55-3 | 99.9% | 308.34 | 100 MG
Palbociclib impurity 20 is an impurity of Palbociclib. This product is intended for research use only and is not for sale to patients.
- High purity of 99.9%
- Molecular weight is 308.34
- Formula: C14H20N4O4
- CAS number: 1774898-55-3
- Appearance: Solid
- SMILES: O=C(N1CCN(C2=C([N+]([O-])=O)C=CN=C2)CC1)OC(C)(C)C
Medchemexpress LLC Ruxolitinib phosphate (synonyms: INCB018424 phosphate) | 1092939-17-7 | MFCD29938883 | 99.97% | C17H18N6.H3PO4 | 500 MG
Ruxolitinib phosphate, also known as INCB018424 phosphate, is a potent inhibitor of JAK1 and JAK2, with IC50s of 3.3 nM and 2.8 nM, respectively. It exhibits over 130-fold selectivity for JAK3, making it a highly selective compound for research applications. This inhibitor also effectively suppresses JAK2V617F-mediated signaling and proliferation, and inhibits HEL cell growth at an EC50 of 186 nM.
- Potent JAK1/2 inhibitor
- Highly selective over JAK3
- Inhibits JAK2V617F-mediated signaling
- Suppresses HEL cell growth
- Increases apoptosis in Ba/F3-EpoR-JAK2V617F cell systems
- Inhibits hematopoietic progenitor cell proliferation
- Reduces tumor burden in vivo without anemia or lymphopenia
![Medchemexpress LLC 1H-Imidazole-5-methanol, 2-butyl-4-chloro-1-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-, potassium salt | 124750-99-8 | 100.0% | 461.00 | 50 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000386489-logo.png-250.jpg){kind=logo}
Medchemexpress LLC 1H-Imidazole-5-methanol, 2-butyl-4-chloro-1-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-, potassium salt | 124750-99-8 | 100.0% | 461.00 | 50 MG
Losartan potassium is an angiotensin II receptor type 1 (AT1) antagonist, competing with the binding of angiotensin II to AT1 with an IC50 of 20 nM. This product is for research use only.
- Angiotensin II receptor type 1 (AT1) antagonist
- IC50 of 20 nM
- Purity 99.98%
- Appearance: white to off-white solid
- Store at 4°C, sealed, away from moisture