Drug Standards
Medchemexpress LLC Niraparib tosylate hydrate | 1613220-15-7 | MFCD28167748 | 100.0% | 510.61 g/mol | C26H30N4O5S | 1 ML
Niraparib tosylate hydrate is the tosylate salt form of niraparib, a potent PARP inhibitor used in biochemical and cell-based research to probe DNA damage response, PARP inhibition, and related combination therapies.
- Potent PARP1 and PARP2 inhibition (IC50s ~3.8 and 2.1 nM).
- Supplied as a 10 mM solution in DMSO (1 mL) and as powder formats for flexible dosing.
- High purity suitable for in vitro studies (product listed as 99.97%).
- CAS registry number 1613220-15-7 for unambiguous identification.
- Suitable for cell treatment and biochemical assays investigating DNA repair pathways.
U.S. Pharmacopeia Neostigmine methyl sulfate, 51-60-5, MFCD00011796, 200 mg
Empirical Formula (Hill Notation): C13H22N2O6S, Molecular Weight: 334.39, Synonym: 3-(N,N-Dimethylcarbamoyloxy)-N,N,N,-trimethylanilinium methyl sulfate.
Medchemexpress LLC Voriconazole impurity 1 | 137330-52-0 | ≥98.0% | C16H14F3N5O | 50 MG
Voriconazole impurity 1 is a chemical compound that serves as an impurity of Voriconazole. It has a molecular weight of 349.31 and a chemical formula of C16H14F3N5O. This solid substance has a purity of ≥98.0% and is intended for research use only.
- Suitable for research applications
- Purity of ≥98.0%
- Solid appearance
- Store at 4°C in sealed, moisture-free conditions
- When in solvent, store at -80°C for 6 months or -20°C for 1 month
Medchemexpress LLC Rivaroxaban impurity 5g
Rivaroxaban impurity 1 is an impurity of Rivaroxaban (HY-50903)
Apexbio Technology LLC Spleen tyrosine kinase (Syk) inhibitor 901119-35-5. MFCD16628163
Spleen tyrosine kinase (Syk) inhibitor 901119-35-5. MFCD16628163
Apexbio Technology LLC Citalopram hydrobromide 59729-32-7 50mg
Citalopram hydrobromide (CAS 59729-32-7) is a selective serotonin reuptake inhibitor (SSRI) that functions by specifically blocking the reuptake of 5-hydroxytryptamine (5-HT) at presynaptic neuronal membranes thereby increasing 5-HT concentrations in the synaptic cleft In vitro studies demonstrate that citalopram hydrobromide exhibits potent nanomolar-level inhibition of 5-HT reuptake in synaptosomal preparations as well as low nanomolar inhibition in rabbit platelet assays This compound is widely utilized in research exploring serotonergic signaling neurotransmission processes and experimental models of depression
Apexbio Technology LLC Esomeprazole Magnesium trihydrate 217087-09-7 100mg
Esomeprazole Magnesium trihydrate (CAS 217087-09-7) is the S-enantiomer of omeprazole formulated as a magnesium salt It functions as a proton pump inhibitor selectively inhibiting the H /K -ATPase enzyme in gastric parietal cells to suppress gastric acid secretion This compound demonstrates pH-dependent stability degrading rapidly in acidic environments while remaining stable under alkaline conditions Controlled clinical studies have demonstrated that esomeprazole reduces the incidence of gastroduodenal ulcers by 70 85% and lowers gastrointestinal bleeding risk by up to 90% in at-risk populations It serves as a valuable tool for research into acid-related gastrointestinal disorders
Apexbio Technology LLC Mevastatin 73573-88-3 10mM (in 1mL DMSO)
Mevastatin (CAS 73573-88-3) is a small-molecule inhibitor targeting 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase It is designed to inhibit cholesterol biosynthesis by competitively binding to the active site of HMG-CoA reductase thereby regulating lipid metabolism Mevastatin exerts its biological activity primarily through reversible competitive inhibition of HMG-CoA reductase In in vitro studies Mevastatin demonstrates strong inhibition of sterol biosynthesis from acetate incorporation with an IC50 value of approximately 1 nM It also inhibits cell proliferation in cultured cells arresting the growth of L cells at concentrations around 1 3 M Based on these pharmacological properties Mevastatin holds research potential in studies exploring cholesterol metabolism cellular proliferation cell cycle progression and lipid regulation mechanisms
Medchemexpress LLC Meropenem trihydrate | 119478-56-7 | 99.9% | 437.51 | 25 MG
Meropenem trihydrate is a carbapenem antibiotic with broad-spectrum antibacterial activity. It inhibits bacterial cell wall synthesis by binding to and inactivating penicillin-binding proteins (PBPs).
- Intrinsically stable to dehydropeptidase-1 (DHP-1) degradation
- Broad-spectrum in vitro activity against many Gram-positive, Gram-negative, and anaerobic bacteria
- Targets β-lactam
- Active against susceptible and resistant N. gonorrhoeae, H. influenzae, and H. ducreyi
Medchemexpress LLC Rosuvastatin lactone | 503610-43-3 | 98.6% | 463.52 | 50 MG
Rosuvastatin lactone is a metabolite of Rosuvastatin, an HMG-CoA inhibitor. It is intended for research use only and is not sold to patients. This product appears as a white to off-white solid.
- Purity: 98.6%
- Molecular weight: 463.52
- Chemical formula: C22H26FN3O5S
- Shipping: Room temperature in continental US
- Storage: Powder at -20°C for 3 years or 4°C for 2 years
- Storage: In solvent at -80°C for 6 months or -20°C for 1 month
- Solubility: 125 mg/mL in DMSO
Medchemexpress LLC Doxylamine succinate | 562-10-7 | 99.8% | C21H28N2O5 | 1 G
Doxylamine succinate is a first-generation antihistamine, acting as a histamine (H1) receptor antagonist. It also functions as a local analgesic and an effective hypnotic agent.
- First-generation antihistamine
- Histamine (H1) receptor antagonist
- Local analgesic agent
- Effective hypnotic agent
Selleck Chemical LLC Cladribine 25mg 4291-63-8 2-CdA, 2-chlorodeoxyadenosine
Cladribine (2-CdA, 2-chlorodeoxyadenosine) is an adenosine deaminase inhibitor for U266, RPMI8226, and MM1.S cells with IC50 of approximately 2.43 ?M, 0.75 ?M, and 0.18 ?M, respectively. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
Medchemexpress LLC Oxibendazole | 20559-55-1 | MFCD00133728 | 99.6% | 50 MG
Oxibendazole is an effective benzimidazole anthelmintic against nematode infections. It induces apoptosis and has anti-cancer and anti-inflammation activities. For research use only; not sold to patients.
- Molecular weight: 249.27
- Formula: C12H15N3O3
- Appearance: Solid
- Color: White to yellow
- Shipping: Room temperature in continental US; may vary elsewhere
- Storage: Powder: -20°C for 3 years, 4°C for 2 years; In solvent: -80°C for 6 months, -20°C for 1 month
- Solubility (In Vitro): DMSO: 5 mg/mL (20.06 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Apexbio Technology LLC Folic acid 59-30-3 5g
Folic acid (CAS 59-30-3) is a water-soluble B9 vitamin structurally derived from Spinacia oleracea It functions as a cofactor in one-carbon transfer reactions facilitating nucleotide synthesis and methylation processes essential for DNA replication and cellular division Due to its involvement in folate metabolism folic acid is frequently utilized in studies of cell proliferation gene expression regulation and metabolic disorders For optimal stability folic acid should be stored in a sealed container under cool dry conditions
Medchemexpress LLC Carbidopa | 28860-95-9 | 99.8% | 10 MM 1 ML
Carbidopa, also known as (S)-(-)-Carbidopa, is a peripheral decarboxylase inhibitor primarily used for research related to Parkinson's disease. It also functions as a selective aryl hydrocarbon receptor (AhR) modulator and has been shown to inhibit pancreatic cancer cell and tumor growth.
- Acts as a peripheral decarboxylase inhibitor
- Functions as a selective aryl hydrocarbon receptor (AhR) modulator
- Demonstrates anticancer activity by inhibiting pancreatic cancer cell and tumor growth
- High purity of 99.84% ensures reliability for research applications
- Comprehensive documentation available, including Data Sheet, COA, SDS, HNMR, RP-HPLC, and Handling Instructions
- Detailed solubility information provided for in vitro and in vivo applications, with protocols for preparing clear stock and working solutions
- Intended for research use only