Ion Chromatography Standards
Apexbio Technology LLC Diuron 330-54-1 1g
Diuron is a small-molecule inhibitor targeting electron transport within chloroplasts It is designed to interfere with photosynthesis by suppressing electron transfer thereby affecting cellular energy metabolism via reduced ATP and NADH synthesis Diuron exerts its biological activity primarily through inhibition of electron transfer in chloroplasts In experimental studies in animal models dietary administration of Diuron at elevated concentrations is associated with increased occurrence of urothelial carcinoma Based on these pharmacological properties Diuron holds research potential in studies of photosynthetic biochemical pathways cellular energy regulation and chemical-induced carcinogenesis
Apexbio Technology LLC Chondroitin sulfate 9007-28-7 1g
Chondroitin sulfate (9007-28-7) is a glycosaminoglycan designed to modulate inflammatory and apoptotic processes thereby regulating extracellular matrix homeostasis Chondroitin sulfate exerts its biological activity primarily by inhibiting inflammatory mediators and reducing cell apoptosis through interactions with various biological molecules Based on these pharmacological properties chondroitin sulfate holds research potential in investigating cartilage degradation inflammatory response mechanisms and therapeutic targets related to joint degeneration and tissue remodeling
Apexbio Technology LLC Nilotinib monohydrochloride monohydrate 923288-90-8 1g
Nilotinib monohydrochloride monohydrate (CAS 923288-90-8) is a selective small molecule inhibitor targeting the BCR-ABL tyrosine kinase By binding to the ATP-binding site of BCR-ABL nilotinib effectively suppresses kinase activity impeding downstream signaling involved in cell proliferation It demonstrates potent inhibitory activity with an IC50 below 30 nM Nilotinib is widely utilized in biomedical research to investigate BCR-ABL-mediated cellular mechanisms and to model therapeutic interventions in chronic myelogenous leukemia and related malignancies
Apexbio Technology LLC Quadrol 102-60-3 1g
Quadrol is an immunostimulatory molecule designed to modulate immune responses by influencing cytokine signaling cascades and chemotaxis of immune cells Quadrol exerts its biological activity primarily by regulating immune cell recruitment and altering inflammatory mediator dynamics Experimental studies employing in vitro cellular models and preclinical animal wound injury models have utilized Quadrol to investigate its effects on immune cell migration inflammatory processes and subsequent tissue regeneration Based on these pharmacological properties Quadrol holds research potential in tissue repair and wound healing applications
Apexbio Technology LLC Clioquinol 130-26-7 1g
Clioquinol (130-26-7) is a small-molecule modulator functioning as a metal-ion chelator It is designed to modulate metal homeostasis thereby affecting metal-dependent cellular pathways Clioquinol exerts its biological activity primarily through chelation of metal ions disrupting iron-mediated enzymatic reactions crucial for fungal and cancer cell growth In in vitro studies Clioquinol demonstrates cytotoxic effects in diverse tumor cell lines with IC50 values generally in the low micromolar range (approximately 1 10 M depending on cell type and conditions) Based on these pharmacological properties Clioquinol holds research potential in antifungal antimicrobial and oncological applications
Waters Corp Waters Chlorate Ion Calibration Standard, 1000 mg/L, 125 mL, H2O
Waters Chlorate Ion Calibration Standard, 1000 mg/L, 125 mL, H2O
Waters Corp WATERS CORPORATION Ion Calibration Standard, Bromate, 1000 mg/L, 125 mL
This is a 125 mL liquid standard containing Bromate at a concentration of 1000 mg/L in H2O. It can be used for primary calibration or to prepare second source calibration check standards. This certified reference material is traceable to NIST Standard Reference Materials and is covered by ISO 17034 accreditation.
- Liquid formulation in H2O, 125 mL volume
- Bromate concentration: 1000 mg/L
- For environmental applications and primary/secondary calibration
- Traceable to NIST SRMs, guaranteed stable for one year
- ISO 17034 accredited CRM
- Supports methods EPA 300.0, EPA 300.1, SM 4110 B
- Store at 4 ± 2°C
- Shelf life: 24 months from manufacture (12 months min. on ship)
- Hazardous material; special freight/charges may apply
Apexbio Technology LLC Tolbutamide 64-77-7 1g
Tolbutamide (CAS 64-77-7) is a small molecule inhibitor known to suppress cyclic adenosine monophosphate (cAMP)-dependent protein kinase activity with an IC50 value of 4 mM It reduces both basal and cAMP-stimulated kinase activities in cellular models including soluble and membrane-bound forms from canine cardiac tissue In adipose tissue tolbutamide s inhibition of cAMP-dependent protein kinase underlies its reported suppression of lipolysis Additionally tolbutamide has been shown to increase connexin43 mRNA levels while decreasing Ki-67 expression in glioma cells suggesting roles in cell proliferation studies This compound is used in research focused on kinase signaling and metabolic regulation
Apexbio Technology LLC Aripiprazole 129722-12-9 1g
Aripiprazole (CAS 129722-12-9) is a non-typical antipsychotic compound characterized as a dopamine-serotonin system stabilizer It acts as a partial agonist at dopamine D2 and serotonin 5-HT1A receptors and exhibits antagonist properties at 5-HT2A receptors Binding studies indicate high affinity to D2 receptors with reported Kd values of 0 34 0 02 nM (agonist radioligand [125I]7-OH-PIPAT) and 0 70 0 22 nM (antagonist [3H]spiperone) In cellular assays aripiprazole inhibits forskolin-induced cAMP accumulation in CHO and HEK-293 cells and suppresses quinpirole-stimulated GTPase activity in rat striatal membranes These properties position aripiprazole as a valuable tool for investigating dopaminergic and serotonergic signaling pathways
![Medchemexpress LLC 2-[(6-amino-9H-purin-9-yl)methyl]-5-methyl-3-(2-methylphenyl)-4(3H)-quinazolinone | 371242-69-2 | MFCD09970845 | >98.0% | 397.4 g/mol | C22H19N7O | 1 ML](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000211422.png-250.jpg)
Medchemexpress LLC 2-[(6-amino-9H-purin-9-yl)methyl]-5-methyl-3-(2-methylphenyl)-4(3H)-quinazolinone | 371242-69-2 | MFCD09970845 | >98.0% | 397.4 g/mol | C22H19N7O | 1 ML
IC-87114 is a selective small-molecule inhibitor of PI3Kδ (p110δ) used in research to probe PI3K signaling and immune-cell functions. It displays reported potency (IC50 ≈ 0.5 μM) and is supplied as a 10 mM solution in a 1 mL vial for analytical and experimental use.
- Selective inhibition of PI3Kδ (p110δ).
- Potent activity with IC50 ~0.5 μM.
- Supplied as a 10 mM solution in a 1 mL vial.
- High purity suitable for research use.
- Applicable to immunology and cell-signaling studies.
Waters Corp Bromide Calibration Standard, 1000 mg/L, 125 mL
This product is a bromide calibration standard from Waters Corporation, designed for accurate calibration in laboratory applications. It provides a precise concentration for reliable analytical measurements.
- Calibrated to 1000 mg/L
- Supplied in a 125 mL volume
- Suitable for various analytical instruments
- Ensures accurate and reliable results
Waters Corp 125 mL Sulphate
Sulfate, Ion Calibration Standard 1000mg/L Martix H2O. This 1000 mg/L standard can be used for primary calibration or to prepare second source calibration check standards. It is traceable to NIST Standard Reference Materials, where available, and is guaranteed stable for one year.