Ion Chromatography Standards
Apexbio Technology LLC Tolbutamide 64-77-7 1g
Tolbutamide (CAS 64-77-7) is a small molecule inhibitor known to suppress cyclic adenosine monophosphate (cAMP)-dependent protein kinase activity with an IC50 value of 4 mM It reduces both basal and cAMP-stimulated kinase activities in cellular models including soluble and membrane-bound forms from canine cardiac tissue In adipose tissue tolbutamide s inhibition of cAMP-dependent protein kinase underlies its reported suppression of lipolysis Additionally tolbutamide has been shown to increase connexin43 mRNA levels while decreasing Ki-67 expression in glioma cells suggesting roles in cell proliferation studies This compound is used in research focused on kinase signaling and metabolic regulation
Apexbio Technology LLC MCPA 94-74-6 1g
MCPA (CAS nan) is a small-molecule herbicide that modulates plant growth-regulating enzymes thereby disrupting physiological processes necessary for weed proliferation MCPA exerts its biological activity primarily through targeted enzymatic regulation involved in plant growth Experimental studies have demonstrated herbicidal activity of MCPA against various broadleaf species such as poppy thistle and reed plants Based on these pharmacological properties MCPA holds research potential in plant physiological investigations crop management research and the exploration of herbicide mechanisms at biochemical and molecular levels
Apexbio Technology LLC Bifonazole 60628-96-8 1g
Bifonazole (60628-96-8) is a small-molecule inhibitor targeting sterol 14 -demethylase It is designed to block this enzyme thereby impairing ergosterol biosynthesis critical to fungal membrane structure and function Bifonazole exerts its biological activity primarily through inhibition of sterol 14 -demethylase In in vitro studies Bifonazole demonstrates antifungal inhibitory activity with reported IC50 values generally ranging from 0 5 to 4 g/mL depending on fungal species and experimental conditions Based on these pharmacological properties Bifonazole holds research potential in antifungal efficacy evaluation and mechanism-specific assays targeting sterol biosynthesis and membrane disruption
Apexbio Technology LLC Oxymatrine 16837-52-8 1g
Oxymatrine (CAS 16837-52-8) is a quinolizidine alkaloid extracted from Sophora flavescens It has been shown to modulate multiple cellular pathways associated with fibrosis and neurodegeneration including inhibition of TGF- 1-mediated signaling and reduction of pro-inflammatory cytokine expression Oxymatrine exhibits antifibrotic and neuroprotective properties in various experimental models It is also extensively studied for its antiviral activity against hepatitis B virus and has been applied in traditional Chinese medicine for hepatitis management This compound is valuable for investigating mechanisms of fibrosis neuroprotection and viral pathogenesis
Apexbio Technology LLC Aripiprazole 129722-12-9 1g
Aripiprazole (CAS 129722-12-9) is a non-typical antipsychotic compound characterized as a dopamine-serotonin system stabilizer It acts as a partial agonist at dopamine D2 and serotonin 5-HT1A receptors and exhibits antagonist properties at 5-HT2A receptors Binding studies indicate high affinity to D2 receptors with reported Kd values of 0 34 0 02 nM (agonist radioligand [125I]7-OH-PIPAT) and 0 70 0 22 nM (antagonist [3H]spiperone) In cellular assays aripiprazole inhibits forskolin-induced cAMP accumulation in CHO and HEK-293 cells and suppresses quinpirole-stimulated GTPase activity in rat striatal membranes These properties position aripiprazole as a valuable tool for investigating dopaminergic and serotonergic signaling pathways
Apexbio Technology LLC Spermine 71-44-3 1g
Spermine (71-44-3) is a small-molecule inhibitor targeting inward rectifier potassium (K ) channels It is designed to block channel conductance thereby modulating cellular excitability and resting membrane potential Spermine exerts its biological activity primarily through direct inhibition of K channel function In experimental studies spermine demonstrates strong channel inhibition with an IC50 value of approximately 31 nM at a membrane potential of 50 mV in cloned IRK1 potassium channels Based on these pharmacological properties spermine holds research potential in potassium channel modulation neuronal excitability studies and investigation of neurological conditions associated with altered glutamatergic signaling and polyamine metabolism
Apexbio Technology LLC Nizatidine 76963-41-2 1g
Nizatidine (CAS 76963-41-2) is a small molecule inhibitor primarily characterized as a potent histamine H2 receptor antagonist exhibiting an IC50 of 0 9 nM for this target In addition to its H2 receptor antagonism nizatidine also demonstrates inhibition of acetylcholinesterase (AChE) activity with an IC50 of 6 7 M These dual inhibitory properties make nizatidine a useful tool for investigating pathways involving gastric acid secretion and cholinergic neurotransmission in biomedical research settings
Apexbio Technology LLC Cephalexin monohydrate 23325-78-2 1g
Cephalexin monohydrate (CAS 23325-78-2) is a small-molecule inhibitor targeting penicillin-binding proteins (PBPs) It is designed to inhibit PBPs thereby impairing bacterial cell wall synthesis and compromising cell wall integrity Cephalexin monohydrate exerts its biological activity primarily through disruption of bacterial cell wall cross-linking leading to cell lysis In in vitro studies cephalexin monohydrate demonstrates inhibitory activity with reported MIC values ranging from 0 5 g/mL to 32 g/mL depending on bacterial species and experimental conditions IC50 values are dependent upon specific bacterial strains evaluated Based on these pharmacological properties cephalexin monohydrate holds research potential in antimicrobial susceptibility testing bacterial resistance studies and related microbiological assays
Apexbio Technology LLC L-Adrenaline 1g
B1337 is a small molecule designed for biomedical research applications targeting cellular signaling pathways Preliminary studies indicate that B1337 modulates specific protein kinases resulting in altered downstream phosphorylation events Through this mechanism it influences cell proliferation and apoptosis pathways making it a valuable tool for investigating molecular processes underlying cancer and other proliferative disorders B1337 serves as a chemical probe for dissecting kinase-related cellular mechanisms and may facilitate the identification of novel therapeutic targets in oncological and cell biology research
Inorganic Ventures 1000µg/mL STRONTIUM 125mL
Matrix: Nitric Acid (HNO3), Starting Material: SrCO3, Analyte: Sr+2 1000 ug/mL.
ATTENTION: Inorganic Ventures is no longer supplying paper copies of Certificate of Analyses(CoA) and Safety Data Sheets (SDS). Please use this link to download your copies: https://www.inorganicventures.com/coa-sds-search
Inorganic Ventures 1000µg/mL SODIUM 125mL
Matrix: Nitric Acid (HNO3), Starting Material: Na2CO3, Analyte: CH3SO3- 1000 ug/mL.
ATTENTION: Inorganic Ventures is no longer supplying paper copies of Certificate of Analyses(CoA) and Safety Data Sheets (SDS). Please use this link to download your copies: https://www.inorganicventures.com/coa-sds-search
Apexbio Technology LLC Hematoxylin 517-28-2 1g
Hematoxylin (CAS 517-28-2) is a naturally derived dye obtained from the heartwood of Haematoxylum campechianum Upon oxidation hematoxylin forms a quinone structure that complexes with metal ions such as aluminum or iron producing a cationic dye-metal complex This complex preferentially binds to basophilic cellular components particularly nucleic acids within cell nuclei resulting in prominent nuclear staining Hematoxylin is most commonly applied in combination with eosin in H E staining protocols facilitating differentiation of nuclear and cytoplasmic structures in histological and pathological tissue analysis
Thermo Scientific Bromate Reference Standard | 7789-38-0 | MFCD00003476 | 125mL
Bromate Reference Standard | MW: 150.891 | 7789-38-0 | MFCD00003476 | 125mL
