Ion Chromatography Standards
Apexbio Technology LLC Nafcillin Sodium 7177-50-6 1g
Nafcillin Sodium (7177-50-6) is a small-molecule inhibitor targeting -lactamase It is designed to reversibly inhibit -lactamase thereby preventing bacterial resistance mediated by hydrolysis of -lactam antibiotics Nafcillin Sodium exerts its biological activity primarily through reversible inhibition of -lactamase In in vitro studies Nafcillin Sodium demonstrates inhibitory activity with an IC50 value of approximately 33 mM Based on these pharmacological properties Nafcillin Sodium holds research potential in investigating -lactamase-mediated antibiotic resistance mechanisms evaluating therapeutic combination strategies and studying bacterial susceptibility profiles
Apexbio Technology LLC Clomiphene citrate 50-41-9 1g
Clomiphene citrate (CAS 50-41-9) is a small-molecule modulator targeting estrogen receptors (ER) It is designed to selectively modulate ER-mediated signaling thereby influencing estrogen-dependent cellular pathways Clomiphene citrate exerts its biological activity primarily through competitive inhibition at estrogen receptors It demonstrates both antiestrogenic and estrogenic activities depending on tissue context Based on these pharmacological properties clomiphene citrate holds research potential in the investigation of estrogen receptor-mediated transcriptional regulation cellular proliferation and differentiation as well as hypothalamic-pituitary-gonadal axis regulation and ovarian follicular maturation in reproductive biology studies
Apexbio Technology LLC Tylosin phosphate 1405-53-4 1g
Tylosin phosphate (CAS 1405-53-4) is a small-molecule inhibitor targeting bacterial ribosomal subunits It is designed to interfere with bacterial translation thereby inhibiting bacterial protein synthesis Tylosin phosphate exerts its biological activity primarily through binding to ribosomal subunits of Gram-positive bacteria In in vitro studies tylosin phosphate demonstrates inhibitory activity with reported IC50 values generally ranging between 0 5 5 g/mL depending on bacterial strain and assay conditions Based on these pharmacological properties tylosin phosphate holds research potential in studies of antibiotic resistance mechanisms antibacterial spectrum evaluation and as an antibiotic additive to explore growth promotion and therapeutic utility in poultry swine and bovine models
Apexbio Technology LLC PNPP 4264-83-9 1g
PNPP (4264-83-9) is a chromogenic non-proteinaceous substrate utilized to assess phosphatase activity It is designed to serve as an analytical reagent for quantifying the activity of alkaline or acid phosphatases through enzymatic hydrolysis resulting in the formation of para-nitrophenol a yellow product with measurable absorbance PNPP exerts its application primarily through substrate conversion upon phosphatase-mediated hydrolysis Based on these properties PNPP holds research potential in enzymatic assays enzyme kinetics studies and the investigation of signal transduction pathways and enzyme-mediated biological processes in biomedical laboratories
Apexbio Technology LLC Pyriproxyfen 95737-68-1 1g
Pyriproxyfen (CAS 95737-68-1) is a small-molecule inhibitor targeting insect juvenile hormone receptors It is designed to interfere with hormone-mediated developmental signaling thereby disrupting endocrine-regulated metamorphosis in insect larvae Pyriproxyfen exerts its biological activity primarily through binding to juvenile hormone receptors impeding physiological maturation and reproduction cycles in target arthropod populations In laboratory experiments pyriproxyfen demonstrates inhibitory activity with IC50 values ranging from approximately 0 1 to 10 M depending on insect species and experimental conditions Based on these pharmacological properties pyriproxyfen holds research potential in agricultural pest management and public health applications involving vector-borne diseases transmitted by arthropods
Inorganic Ventures 1.8 M Methanesulfonic Acid
Inorganic Ventures' 1.8 M Methanesulfonic Acid for ICP-MS is a 500mL reference material set in a water matrix for stability. This eluent is Traceable to NIST and manufactured in accordance with our stringent Quality Assurance guidelines. See Certificate of Analysis for expiration.
ATTENTION: Inorganic Ventures is no longer supplying paper copies of Certificate of Analyses(CoA) and Safety Data Sheets (SDS). Please use this link to download your copies: https://www.inorganicventures.com/coa-sds-search
Inorganic Ventures QC INSTR PERF CHK STD 125mL
Inorganic Ventures' QC Standard / Instrument Performance Check is a 125mL certified reference material set in a water matrix for stability. This standard is Traceable to NIST and manufactured in accordance with our stringent Quality Assurance guidelines. See Certificate of Analysis for expiration.
ATTENTION: Inorganic Ventures is no longer supplying paper copies of Certificate of Analyses(CoA) and Safety Data Sheets (SDS). Please use this link to download your copies: https://www.inorganicventures.com/coa-sds-search
Apexbio Technology LLC Tolnaftate 2398-96-1 1g
Tolnaftate (2398-96-1) is a small-molecule inhibitor targeting fungal squalene epoxidase It is designed to block this key enzyme thereby disrupting ergosterol biosynthesis within fungal cell membranes and inhibiting fungal proliferation Tolnaftate exerts its biological activity primarily through inhibition of squalene epoxidase In in vitro studies Tolnaftate demonstrates antifungal inhibition with an IC50 value typically between 0 01 to 2 g/mL depending on fungal strain Based on these pharmacological properties Tolnaftate holds research potential in evaluating drug sensitivity profiles investigating fungal resistance mechanisms and validating antifungal drug targets
Apexbio Technology LLC Trichlormethiazide 133-67-5 1g
Trichlormethiazide is a small-molecule inhibitor targeting the sodium-chloride cotransporter (NCC) It is designed to inhibit NCC in the distal convoluted tubules thereby decreasing sodium and chloride reabsorption and modulating fluid and electrolyte balance Trichlormethiazide exerts its biological activity primarily through inhibition of sodium and chloride reabsorption Based on these pharmacological properties Trichlormethiazide holds research potential in studies of electrolyte and fluid regulation hypertension-related pathophysiology and renal function as well as the investigation of renal tubular sodium handling and screening interventions affecting nephron sodium transport processes in biological models
Apexbio Technology LLC Amsacrine 51264-14-3 1g
Amsacrine (CAS 51264-14-3) also known as m-AMSA is a small-molecule inhibitor of DNA topoisomerase II It is widely used as an antineoplastic agent in biomedical research particularly for investigating the treatment of lymphomas and acute leukemias Amsacrine exhibits cytotoxic effects across various cancer cell lines with reported IC50 values of 190 2 27 4 ng/ml 46 1 3 9 ng/ml and 22 6 3 1 ng/ml in HT1376 RT112 and RT4 bladder cancer cells and 11 8 2 0 ng/ml 5 0 0 4 ng/ml and 11 7 1 5 ng/ml in the 833K Susa and GH testicular cancer cell lines respectively Testicular cancer cell lines display greater sensitivity to Amsacrine-induced inhibition than bladder cancer cell lines This compound is valuable for studying DNA damage mechanisms and the cellular response to topoisomerase II inhibition
Apexbio Technology LLC WZ811 55778-02-4 1g
WZ811 (CAS 55778-02-4) is a small molecule antagonist targeting the CXC chemokine receptor 4 (CXCR4) Structurally composed of two aromatic amine groups WZ811 inhibits the binding of TN14003 to CXCR4 with an EC50 of 0 3 nM and disrupts stromal cell-derived factor 1 (SDF-1)-mediated CXCR4 signaling In cAMP assays WZ811 significantly attenuates SDF-1-induced cAMP responses and impedes SDF-1-driven Matrigel invasion (EC50 5 2 nM) Given CXCR4 s involvement in infection inflammation and various diseases WZ811 serves as a valuable tool for interrogating CXCR4-related biological processes and disease models and has been reported to display modest anti-HIV activity in cell cultures