Acetylides

eMolecules​ 2055042-83-4 | Propargyl-PEG9-bromide | Broadpharm | MFCD29079385 | 515.438 | C21H39BrO9 | 98.000 | BrCCOCCOCCOCCOCCOCCOCCOCCOCCOCC#C | 500mg | 298819246

Propargyl-PEG9-bromide | Broadpharm | 2055042-83-4 | MFCD29079385 | 515.438 | C21H39BrO9 | 98.000 | BrCCOCCOCCOCCOCCOCCOCCOCCOCCOCC#C | 500mg | 298819246

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eMolecules​ 866683-52-5 | 3-Bromo-5-ethynylpyridine | Combi-Blocks | MFCD10698137 | 182.020 | C7H4BrN | 95.000 | Brc1cncc(c1)C#C | 1g | 457921716

3-Bromo-5-ethynylpyridine | Combi-Blocks | 866683-52-5 | MFCD10698137 | 182.020 | C7H4BrN | 95.000 | Brc1cncc(c1)C#C | 1g | 457921716

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Medchemexpress LLC E -Pent-2-enal 500g

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(E)-Pent-2-enal has a pungent fruity odor This compound is commonly used in the flavor and fragrance industry because of its strong aroma often described as fresh and green Furthermore (E)-Pent-2-enal can be used as an intermediate in the synthesis of various organic compounds including pharmaceuticals and agrochemicals Its unique chemical properties make it an important ingredient in many commercial products including perfumes air fresheners and cleaners

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Medchemexpress LLC N-(Propargyl-PEG4-carbonyl)-N-bis(PEG1-methyl ester) | 2112732-01-9 | 519.58 | 100 MG

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N-(Propargyl-PEG4-carbonyl)-N-bis(PEG1-methyl ester) is a PEG-based PROTAC linker used in the synthesis of PROTACs. It functions as a click chemistry reagent, featuring an Alkyne group capable of copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. PROTACs themselves contain two distinct ligands linked together, one targeting an E3 ubiquitin ligase and the other the protein of interest, utilizing the intracellular ubiquitin-proteasome system for selective target protein degradation. This product is for research use only.

• PEG-based PROTAC linker
• Used in PROTAC synthesis
• Click chemistry reagent
• Contains an alkyne group
• Capable of copper-catalyzed azide-alkyne cycloaddition (CuAAc)
• Reacts with azide-containing molecules
• Exploits ubiquitin-proteasome system
• Selectively degrades target proteins

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eMolecules​ 1066-54-2 | Ethynyltrimethylsilane | AA Blocks LLC | MFCD00008569 | 98.220 | C5H10Si | 0.000 | C[Si](C)(C)C#C | 500g | 874013359

Ethynyltrimethylsilane | AA Blocks LLC | 1066-54-2 | MFCD00008569 | 98.220 | C5H10Si | 0.000 | C[Si](C)(C)C#C | 500g | 874013359

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Medchemexpress LLC 4,7,10,13,16,19,22-heptaoxapentacos-24-ynoic acid | 2093154-00-6 | MFCD30536167 | 95.0% | 392.44 | C18H32O9 | 100 MG

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Propargyl-PEG7-acid is a PEG7-based linker bearing a terminal propargyl (alkyne) group used for assembling PROTACs, synthesizing antibody-drug conjugates, and performing copper-catalyzed azide-alkyne click reactions.

• Terminal alkyne for CuAAC click chemistry
• PEG7 spacer improves solubility and linker flexibility
• Suitable for PROTAC and ADC linker synthesis
• Available in multiple pack sizes for scalable use

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eMolecules​ 1261791-09-6 | 2-Chloro-6-(trifluoromethoxy)benzyl alcohol | Apollo Scientific | MFCD18393817 | 226.580 | C8H6ClF3O2 | 95.000 | OCc1c(Cl)cccc1OC(F)(F)F | 1g | 562428505

2-Chloro-6-(trifluoromethoxy)benzyl alcohol | Apollo Scientific | 1261791-09-6 | MFCD18393817 | 226.580 | C8H6ClF3O2 | 95.000 | OCc1c(Cl)cccc1OC(F)(F)F | 1g | 562428505

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eMolecules​ 1066-54-2 | (Trimethylsilyl)acetylene | Oakwood Chemical | MFCD00008569 | 98.220 | C5H10Si | 98.000 | C[Si](C)(C)C#C | 1g | 600900009

(Trimethylsilyl)acetylene | Oakwood Chemical | 1066-54-2 | MFCD00008569 | 98.220 | C5H10Si | 98.000 | C[Si](C)(C)C#C | 1g | 600900009

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eMolecules​ 1066-54-2 | Ethynyltrimethylsilane | AA Blocks LLC | MFCD00008569 | 98.220 | C5H10Si | 0.000 | C[Si](C)(C)C#C | 25g | 410166967

Ethynyltrimethylsilane | AA Blocks LLC | 1066-54-2 | MFCD00008569 | 98.220 | C5H10Si | 0.000 | C[Si](C)(C)C#C | 25g | 410166967

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Medchemexpress LLC 4,7,10,13,16,19-hexaoxadocos-21-ynoic acid | 1951438-84-8 | MFCD28950778 | >=97.0% | 348.39 | C16H28O8 | 25 MG

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Propargyl-PEG6-acid is a polyethylene glycol (PEG6) linker bearing a terminal propargyl (alkyne) and a terminal carboxylic acid. It is used as a click-chemistry reagent for copper-catalyzed azide-alkyne cycloaddition (CuAAC) and as a linker in the synthesis of antibody-drug conjugates (ADCs) and proteolysis-targeting chimeras (PROTACs).

• Contains a terminal alkyne for CuAAC click reactions.
• Terminal carboxylic acid enables amide coupling and conjugation.
• Molecular weight 348.39; chemical formula C16H28O8.
• Suitable for use as an ADC and PROTAC linker in bioconjugation workflows.
• Recommended storage: pure material at -20°C for long-term stability.

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Medchemexpress LLC Propargyl-PEG2-amine | 944561-44-8 | 98.9% | 143.18 g/mol | C7H13NO2 | 500 MG

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Propargyl-PEG2-amine is a PEG-based linker used as a non-cleavable linker in antibody-drug conjugate (ADC) synthesis and as a PEG-based PROTAC linker. It is supplied as a liquid reagent for bioconjugation and medicinal chemistry applications.

• Non-cleavable ADC and PROTAC linker for bioconjugation.
• PEG2 spacer with propargyl and amine functional groups.
• High purity (98.9%) suitable for synthesis.
• Liquid appearance, colorless to light yellow.
• Molecular weight 143.18 g/mol; formula C7H13NO2.
• Storage: refrigerate at 4°C, protect from light; in solvent store at -80°C (6 months) or -20°C (1 month).

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Medchemexpress LLC Propargyl-PEG3-OCH2-Boc | 888010-02-4 | 302.36 | 50 MG

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Propargyl-PEG3-OCH2-Boc is a PEG-based PROTAC linker designed for use in the synthesis of PROTACs. It functions as a click chemistry reagent due to its Alkyne group, enabling copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. This compound is strictly for research use and is not intended for patient treatment.

• PEG-based PROTAC linker for PROTAC synthesis
• Click chemistry reagent with Alkyne group
• Enables copper-catalyzed azide-alkyne cycloaddition (CuAAc)
• Reacts with molecules containing Azide groups
• Chemical formula: C15H26O6
• Intended for research use only

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eMolecules​ 1036204-60-0 | Propargyl-PEG6-alcohol | Broadpharm | MFCD27635181 | 276.329 | C13H24O6 | 98.000 | OCCOCCOCCOCCOCCOCC#C | 1g | 229582392

Propargyl-PEG6-alcohol | Broadpharm | 1036204-60-0 | MFCD27635181 | 276.329 | C13H24O6 | 98.000 | OCCOCCOCCOCCOCCOCC#C | 1g | 229582392

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Medchemexpress LLC Propargyl-PEG8-acid | 2055014-94-1 | 98.0% | 436.49 g/mol | C20H36O10 | 100 MG

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Propargyl-PEG8-acid is a propargyl-functionalized polyethylene glycol (PEG8) carboxylic acid linker designed for bioconjugation and linker chemistry. It provides a PEG8 spacer with a terminal alkyne for click chemistry and a carboxylic acid for coupling reactions; it is supplied as a high-purity solid with defined stability and storage requirements.

• Propargyl terminal alkyne suitable for copper-catalyzed click chemistry.
• Peg8 spacer improves solubility and flexibility in conjugates.
• Carboxylic acid functionality enables amide coupling and derivatization.
• High purity (approximately 98.0%) for reliable synthetic performance.
• Molecular weight 436.49 g/mol, formula C20H36O10.
• Available in small-scale packs (100 mg) and larger sizes for scale-up.
• Store at -20°C under inert atmosphere; in solvent, follow recommended cold storage times.

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Medchemexpress LLC Propargyl-PEG4-CH2CO2-NHS | 2144777-76-2 | 343.33 | 100 MG

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Propargyl-PEG4-CH2CO2-NHS (compound P-7) is a PEG derivative containing a propargyl group and an NHS group. It is an ADC linker used in the synthesis of antibody-drug conjugates (ADCs). It is also categorized as a click chemistry reagent, possessing an alkyne group that enables it to participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with azide-containing molecules.

• PEG derivative with propargyl and NHS groups.
• Acts as an ADC linker for synthesizing antibody-drug conjugates.
• Functions as a click chemistry reagent.
• Contains an alkyne group, allowing for copper-catalyzed azide-alkyne cycloaddition (CuAAc) with azide groups.

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