Acetylides
eMolecules 33577-99-0 | Ambeed | Methyl 2-ethynylbenzoate | 250mg | 552687157 | A272766 | MFCD12547057 | 160.172 | C10H8O2
Ambeed | 1-(Bromomethyl)-3-(methylsulfonyl)benzene | 100mg | 517260041 | A144030 | 82657-76-9 | MFCD12025160 | 249.120 | C8H9BrO2S
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Medchemexpress LLC Propargyl-PEG8-acid | 2055014-94-1 | 98.0% | 436.49 | C20H36O10 | 250 MG
Propargyl-PEG8-acid is an alkyne-functionalized PEG8 linker used as a cleavable linker in PROTAC and antibody-drug conjugate synthesis. It functions as a click chemistry reagent (terminal alkyne) for copper-catalyzed azide-alkyne cycloaddition and is supplied with high purity for medicinal chemistry applications.
- Alkyne-terminated PEG8 linker suitable for CuAAC click reactions.
- Cleavable linker for PROTAC and antibody-drug conjugate (ADC) assembly.
- Molecular formula C20H36O10; molecular weight 436.49.
- High purity laboratory grade, suitable for synthesis.
- Available in multiple pack sizes including 250 mg.
Medchemexpress LLC Propargyl-PEG12-OH 100mg | 1036204-61-1 | 584.69 | C27H52O13 | 100 MG
Propargyl-PEG12-OH is a PEG12-based propargyl (alkyne) linker used as a click-chemistry reagent for PROTAC synthesis and bioconjugation. It contains a terminal alkyne that undergoes copper-catalyzed azide-alkyne cycloaddition (CuAAC) to conjugate with azide-containing molecules. Supplied for research use in multiple pack sizes.
- Contains terminal alkyne for CuAAC (click chemistry).
- PEG12 spacer provides water solubility and conformational flexibility.
- High purity suitable for organic synthesis and conjugation reactions.
- Available in mg to g pack sizes for lab-scale synthesis.
STA Pharmaceutical 2'-propargyl G(iBu) amidite | 5 g | CAS 171486-61-6 | MDL MFCD28976150
2'-propargyl G(iBu) amidite is a Amidite reagent (Subcategory: 2'-propargyl Series) sold by WuXi TIDES. Offered in 5 g. Store at -20 °C. SDS available for reference.
Specifications
- CAS: 171486-61-6
- MDL: MFCD28976150
- InChIKey: AGWGPRXHCUPJJO-VCGWOZLGSA-N
- Molecular Weight: 893.978761998
- Molecular Formula: C47H56N7O9P
- Purity: ≥95%
- Container Type: 100 mL Glass (Septum)
- Pack Size: 5 g
- Net Weight: 5 g
- Gross Weight: 100.4 g
- Commodity Code: 29349990
- Country Of Origin: China
- IUPAC: (2R,3R,4R,5R)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-5-(2-isobutyramido-6-oxo-1,6-dihydro-9H-purin-9-yl)-4-(prop-2-yn-1-yloxy)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite
- SMILES: CC(N(P(O[C@H]1[C@H]([C@@H](O[C@@H]1COC(C2=CC=C(C=C2)OC)(C3=CC=C(C=C3)OC)C4=CC=CC=C4)N5C(N=C(N6)NC(C(C)C)=O)=C(N=C5)C6=O)OCC#C)OCCC#N)C(C)C)C
![Medchemexpress LLC Propanoic acid, 3-[2-[[2-(2-propyn-1-yloxy)ethyl]dithio]ethoxy]- | 1807503-85-0 | >95.0% | 264.36 g/mol | C10H16O4S2 | 100 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000204167.png-250.jpg)
Medchemexpress LLC Propanoic acid, 3-[2-[[2-(2-propyn-1-yloxy)ethyl]dithio]ethoxy]- | 1807503-85-0 | >95.0% | 264.36 g/mol | C10H16O4S2 | 100 MG
Propargyl-PEG1-SS-PEG1-acid is a cleavable two-unit polyethylene glycol (PEG) linker containing a propargyl (alkyne) group and a disulfide bond, terminating in a carboxylic acid. It is intended for click-chemistry-enabled bioconjugation and as a reducible linker in antibody-drug conjugate synthesis.
- Cleavable disulfide linkage for reductive release.
- Alkyne handle compatible with copper-catalyzed azide-alkyne cycloaddition.
- Carboxylic acid terminus for amide coupling or further functionalization.
- Purity typically ≥95%.
- Available in multiple sizes, including 100 mg.
- Stable when stored under recommended temperatures.
Medchemexpress LLC Propargyl-PEG8-NH2 | 1196732-52-1 | 98.0% | 10 G
Propargyl-PEG8-NH2 is a PEG-based PROTAC linker used in the synthesis of PROTACs. It is also a non-cleavable ADC linker utilized in the synthesis of antibody-drug conjugates (ADCs). This compound is a click chemistry reagent, containing an Alkyne group that can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
- Peg-based protac linker
- Non-cleavable adc linker
- Click chemistry reagent
- Contains an alkyne group
- Undergoes copper-catalyzed azide-alkyne cycloaddition (CuAAc)
Medchemexpress LLC Boc-propargylamine | 92136-39-5 | 99.5% | C8H13NO2 | 10 G
N-Boc-Propargylamine is a biochemical reagent used as a biological material or organic compound for life science-related research. It is a click chemistry reagent, containing an alkyne group, that can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing azide groups.
- Used to prepare triazolobenzylidene-thiazolopyrimidines
- Acts as CDC25 phosphatase inhibitors
- Used for the synthesis of beta-glucan polysaccharide analogs
- Involved in the Pauson-Khand (PK) reaction to prepare 4,5-dissubstituted cyclopentenones
eMolecules 106-96-7 | Propargyl bromide | Broadpharm | MFCD00000241 | 118.961 | C3H3Br | 0.000 | BrCC#C | 500g | 795361322
Propargyl bromide | Broadpharm | 106-96-7 | MFCD00000241 | 118.961 | C3H3Br | 0.000 | BrCC#C | 500g | 795361322
eMolecules 874821-52-0 | 5-Chloro-2-(trifluoromethoxy)benzyl alcohol | Apollo Scientific | MFCD11519357 | 226.580 | C8H6ClF3O2 | 95.000 | OCc1cc(Cl)ccc1OC(F)(F)F | 1g | 562461133
5-Chloro-2-(trifluoromethoxy)benzyl alcohol | Apollo Scientific | 874821-52-0 | MFCD11519357 | 226.580 | C8H6ClF3O2 | 95.000 | OCc1cc(Cl)ccc1OC(F)(F)F | 1g | 562461133
Medchemexpress LLC Propargyl-PEG5-Br | 1287660-83-6 | 339.22 | 250 MG
Propargyl-PEG5-Br is a PEG-based PROTAC linker designed for the synthesis of PROTACs. It also functions as a click chemistry reagent, featuring an alkyne group that enables copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing azide groups. This linker is ideal for researchers developing novel protein degradation therapeutics.
- PEG-based PROTAC linker
- Used in PROTAC synthesis
- Functions as a click chemistry reagent
- Contains an alkyne group
- Enables copper-catalyzed azide-alkyne cycloaddition (CuAAc) with azide groups
Medchemexpress LLC Boc-Propargylamine | 92136-39-5 | 99.5% | C8H13NO2 | 25 G
Boc-Propargylamine is a biochemical reagent suitable for use as a biological material or organic compound in life science research. It functions as a click chemistry reagent, containing an Alkyne group that can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules possessing Azide groups.
- Used to prepare triazolobenzylidene-thiazolopyrimidines, which act as CDC25 phosphatase inhibitors.
- Used for the synthesis of beta-glucan polysaccharide analogs.
- Involved in the Pauson-Kh reaction of norbornadiene and N-Boc-propargylamine to prepare 4,5-dissubstituted cyclopentenones.
=O | 1g | 562428509](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502154630.JPG-250.jpg)
eMolecules 2149598-58-1 | 3-Fluoro-2-(trifluoromethoxy)-6-nitroaniline | Apollo Scientific | MFCD30723447 | 240.114 | C7H4F4N2O3 | 95.000 | Nc1c(OC(F)(F)F)c(F)ccc1[N+]([O-])=O | 1g | 562428509
3-Fluoro-2-(trifluoromethoxy)-6-nitroaniline | Apollo Scientific | 2149598-58-1 | MFCD30723447 | 240.114 | C7H4F4N2O3 | 95.000 | Nc1c(OC(F)(F)F)c(F)ccc1[N+]([O-])=O | 1g | 562428509
eMolecules 4-Chloro-2-(trifluoromethoxy)-DL-phenylalanine | 1435806-19-1 | MFCD19687214 | 1g
Apollo Scientific | 4-Chloro-2-(trifluoromethoxy)-DL-phenylalanine | 1g | 562459894 | PC302857 | | 1435806-19-1 | MFCD19687214 | 283.630 | C10H9ClF3NO3
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eMolecules Building Block Tool
eMolecules 1391008-15-3 | 2-Fluoro-4-(trifluoromethoxy)-DL-phenylalanine | Apollo Scientific | MFCD16652500 | 267.180 | C10H9F4NO3 | 95.000 | NC(Cc1ccc(OC(F)(F)F)cc1F)C(O)=O | 1g | 562456457
2-Fluoro-4-(trifluoromethoxy)-DL-phenylalanine | Apollo Scientific | 1391008-15-3 | MFCD16652500 | 267.180 | C10H9F4NO3 | 95.000 | NC(Cc1ccc(OC(F)(F)F)cc1F)C(O)=O | 1g | 562456457