Hydrobromides
Medchemexpress LLC Pifithrin-α hydrobromide | 63208-82-2 | C16H19BrN2OS | 500 MG
Pifithrin-α hydrobromide is a p53 inhibitor that blocks its transcriptional activity, preventing cells from apoptosis. It also acts as an aryl hydrocarbon receptor (AhR) agonist. This water-soluble compound can suppress p53 protein transcription and glucose oxidase (GOX)-induced p53 protein increase.
- Blocks p53 transcriptional activity
- Prevents cells from apoptosis
- Acts as an aryl hydrocarbon receptor (AhR) agonist
- Suppresses p53 protein transcription
- Blocks GOX-induced Bcl-2 protein reduction and prevents Bax increase
- Binds to AhR and activates reporter activity
- Up-regulates classic AhR target gene CYP1A1
eMolecules 180695-79-8 | TERT-BUTYL4-BROMOPIPERIDINE-1-CARBOXYLATE | AstaTech | MFCD04115039 | 264.163 | C10H18BrNO2 | 97.000 | CC(C)(C)OC(=O)N1CCC(Br)CC1 | 25g | 112534061
TERT-BUTYL4-BROMOPIPERIDINE-1-CARBOXYLATE | AstaTech | 180695-79-8 | MFCD04115039 | 264.163 | C10H18BrNO2 | 97.000 | CC(C)(C)OC(=O)N1CCC(Br)CC1 | 25g | 112534061
Medchemexpress LLC (RS)-AMPA hydrobromide | 171259-81-7 | 99.5% | 267.08 g/mol | C7H11BrN2O4 | 10 MG
(RS)-AMPA hydrobromide is the hydrobromide salt of (RS)-AMPA, a glutamate analogue and selective agonist of AMPA-type glutamate receptors. Supplied as a white to off-white solid for research use in neuroscience and pharmacology studies where a water-soluble AMPA receptor agonist is required.
- Selective AMPA receptor agonist.
- CAS number 171259-81-7.
- Molecular weight 267.08 g/mol.
- Purity 99.5%.
- White to off-white solid.
- Solubility: DMSO 50 mg/mL; H2O 5 mg/mL (may require ultrasonic).
- Storage: sealed at 4°C; in solvent store at -80°C (6 months) or -20°C (1 month).
Medchemexpress LLC Burixafor (hydrobromide) | 1191450-19-7 | 98.0% | 769.01 | 1 ML
Burixafor hydrobromide is a potent CXCR4 antagonist that inhibits the binding of CXCL12 to CXCR4 and blocks downstream signaling. It mobilizes CD34+ hematopoietic stem/progenitor cells from bone marrow to peripheral blood. This compound is used for research on autologous hematopoietic stem cell transplantation (ASCT).
- Potent CXCR4 antagonist with a pIC50 of 7.4.
- Inhibits binding of CXCL12 to CXCR4.
- Mobilizes CD34+ hematopoietic stem/progenitor cells.
- Useful for research on autologous hematopoietic stem cell transplantation.
Apexbio Technology LLC SR 95531 hydrobromide 104104-50-9 50mg
SR 95531 hydrobromide (CAS 104104-50-9) also known as Gabazine is a selective competitive antagonist of the GABAA receptor By binding to the GABA recognition site on the receptor it blocks the activation induced by -aminobutyric acid (GABA) Experimental studies report an inhibitory concentration (IC50) of approximately 0 2 M for GABAA receptor-mediated responses Widely utilized in neuroscience research Gabazine is applied to investigate the physiological and pathological roles of GABAA receptor-mediated synaptic transmission neural network modulation and neurotransmitter regulation
Medchemexpress LLC 2-iminobiotin hydrobromide | 76985-52-9 | 98.0% | 324.24 g·mol⁻1 | C10H18BrN3O2S | 1 ML
2-Iminobiotin hydrobromide is a biotin analog and a reversible inhibitor of nitric oxide synthases used in research to probe NO signaling and neuroprotection. It is supplied as a 10 mM solution in DMSO (1 mL) and has reported Ki values of 21.8 μM for murine iNOS and 37.5 μM for rat n-cNOS. For research use only; not for human or therapeutic applications.
- Biotin analog that reversibly inhibits nitric oxide synthases (NOS).
- Reported Ki: 21.8 μM (murine iNOS) and 37.5 μM (rat n-cNOS).
- Supplied as 10 mM solution in DMSO, 1 mL vial.
- Molecular weight 324.24 g·mol⁻1; formula C10H18BrN3O2S.
- Purity: 98.0%.
- Suitable for research on NO signaling, immunology, and neuroprotection.
Medchemexpress LLC Fatostatin hydrobromide | 298197-04-3 | MFCD00760867 | 99.52% | C18H19BrN2S | 25 MG
Fatostatin hydrobromide (125B11 hydrobromide) is a specific inhibitor of SREBP activation. It impairs the activation of SREBP-1 and SREBP-2 by binding to SCAP (SREBP cleavage-activating protein), which inhibits the ER-Golgi translocation of SREBPs. This action leads to a decrease in the transcription of lipogenic genes in cells.
- Specific inhibitor of SREBP activation.
- Impairs activation of SREBP-1 and SREBP-2.
- Inhibits ER-Golgi translocation of SREBPs.
- Decreases transcription of lipogenic genes.
- Exhibits antitumor properties.
- Lowers hyperglycemia in ob/ob mice.
Medchemexpress LLC Galanthamine hydrobromide (Galantamine hydrobromide) | 1953-04-4 | 99.9% | C17H22BrNO3 | 500 MG
Galanthamine hydrobromide is a selective, reversible, competitive, alkaloid AChE inhibitor with an IC50 of 0.35 μM. It also acts as a potent allosteric potentiating ligand (APL) for human α3β4, α4β2, and α6β4 nicotinic receptors (nAChRs). This compound is primarily developed for research into Alzheimer's disease (AD).
- Selective, reversible, competitive alkaloid AChE inhibitor
- Potent allosteric potentiating ligand of human α3β4, α4β2, α6β4 nicotinic receptors (nAChRs)
- Developed for Alzheimer's disease (AD) research
- IC50 of 0.35 μM for AChE
![eMolecules 6674-22-2 | 1,8-Diazabicyclo[5.4.0]undec-7-ene | Oakwood Chemicals | MFCD00006930 | 152.241 | C9H16N2 | 99.000 | C1CN=C2CCCCCN2C1 | 100g | 480122916](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000162048.jpg-250.jpg)
eMolecules 6674-22-2 | 1,8-Diazabicyclo[5.4.0]undec-7-ene | Oakwood Chemicals | MFCD00006930 | 152.241 | C9H16N2 | 99.000 | C1CN=C2CCCCCN2C1 | 100g | 480122916
1,8-Diazabicyclo[5.4.0]undec-7-ene | Oakwood Chemicals | 6674-22-2 | MFCD00006930 | 152.241 | C9H16N2 | 99.000 | C1CN=C2CCCCCN2C1 | 100g | 480122916
eMolecules 31582-45-3 | 2,2,6,6-TETRAMETHYLPIPERIDIN-4-YL METHACRYLATE | AstaTech | MFCD06200811 | 225.332 | C13H23NO2 | 95.000 | CC(=C)C(=O)OC1CC(C)(C)NC(C)(C)C1 | 1g | 818504080
2,2,6,6-TETRAMETHYLPIPERIDIN-4-YL METHACRYLATE | AstaTech | 31582-45-3 | MFCD06200811 | 225.332 | C13H23NO2 | 95.000 | CC(=C)C(=O)OC1CC(C)(C)NC(C)(C)C1 | 1g | 818504080
Medchemexpress LLC (RS)-AMPA hydrobromide | 171259-81-7 | MFCD00055183 | 99.5% | 267.08 g·mol⁻¹ | C7H11BrN2O4 | 5 MG
(RS)-AMPA hydrobromide is a research-grade glutamate analogue that acts as a potent, selective agonist of AMPA-type ionotropic glutamate receptors. Supplied as a solid hydrobromide salt with high purity, it is intended for use in neuropharmacology, electrophysiology, and receptor pharmacology studies. The compound is soluble in DMSO and water (sonication recommended) and should be stored protected from moisture under refrigerated or low-temperature conditions as specified by the supplier.
- Potent, selective agonist of AMPA receptors.
- Hydrobromide salt increases aqueous solubility.
- High purity suitable for research and analytical applications.
- Soluble in DMSO and water; sonication recommended.
- Stable when stored sealed and protected from moisture.
- Provided in small milligram quantities for experimental use.
eMolecules 180695-79-8 | N-Boc-4-bromopiperidine | ChemScene | MFCD04115039 | 264.163 | C10H18BrNO2 | 97.000 | CC(C)(C)OC(=O)N1CCC(Br)CC1 | 1g | 894452969
N-Boc-4-bromopiperidine | ChemScene | 180695-79-8 | MFCD04115039 | 264.163 | C10H18BrNO2 | 97.000 | CC(C)(C)OC(=O)N1CCC(Br)CC1 | 1g | 894452969
Medchemexpress LLC m-tyramine hydrobromide | 38449-59-1 | 98.5% | 218.09 g·mol-1 | C8H12BrNO | 5 MG
m-Tyramine hydrobromide is the hydrobromide salt of m-tyramine, an endogenous trace amine neuromodulator reported to interact with adrenergic and dopaminergic receptors. It is supplied for research and analytical applications, with reported analytical purity and supporting documentation for use as a reference standard.
- Endogenous trace amine neuromodulator with adrenergic and dopaminergic activity.
- Analytical grade with high purity suitable for research and standards.
- Available in multiple small-scale pack sizes and as a solution in DMSO.
- Supplied with certificate of analysis and RP-HPLC documentation.
- Useful as a reference standard and biochemical research reagent.