Hydrochlorides
Sigma Aldrich Fine Chemicals Biosciences Procaine hydrochloride >=97% | 51-05-8 | MFCD00013000 | 100G
Procaine hydrochloride >=97% | Purity: >=97% | Mol Wt: 272.77 | 51-05-8 | MFCD00013000 | 100G
Medchemexpress LLC N-desmethyl venlafaxine hydrochloride | 93413-90-2 | MFCD18711349 | 99.9% | C16H26ClNO2 | 10MG
Wy-45494 hydrochloride (N-desmethyl venlafaxine hydrochloride) is the hydrochloride salt of a minor active metabolite of the SNRI venlafaxine. It is supplied as an analytical standard for research, quality control, and method development in chromatographic and mass spectrometry applications.
- High purity: 99.85% (analytical standard).
- Suitable for HPLC, GC, and MS method development and quantitation.
- Hydrochloride salt form provides enhanced solubility and stability.
- Chemical formula C16H26ClNO2 and molecular weight ~299.84 g/mol.
- Intended for research use only; not for human or veterinary use.
Medchemexpress LLC CP-100356 hydrochloride | 142715-48-8 | MFCD00911858 | 99.1% | 597.10 g·mol⁻1 | C31H37ClN4O6 | 100 MG
CP-100356 hydrochloride is a research-grade P-glycoprotein (MDR1) and BCRP inhibitor provided as the monohydrochloride salt for in vitro and preclinical studies. It is used to inhibit efflux transporters in cell-based assays to improve intracellular exposure and to evaluate transporter-mediated clearance. The compound is supplied as a solid powder and is available in small pack sizes suitable for screening and experimental use.
- Research-grade P-gp and BCRP inhibitor for cellular assays.
- Provided as the monohydrochloride salt in solid powder form.
- High reported purity suitable for biochemical and cell-based studies.
- Molecular weight 597.10 g·mol⁻1 and formula C31H37ClN4O6.
- Available in small pack sizes and solution formats for flexible use.
Medchemexpress LLC K-604 dihydrochloride | 217094-32-1 | MFCD30738203 | >=98.0% | 575.64 | C23H32Cl2N6OS3 | 25 MG
K-604 dihydrochloride is a research reagent that selectively inhibits acyl-CoA:cholesterol acyltransferase 1 (ACAT-1), with a reported IC50 of 0.45 ± 0.06 μM. Supplied as the dihydrochloride salt, it is intended for biochemical and cellular studies probing ACAT-1 activity and cholesterol esterification pathways.
- Selective ACAT-1 inhibitor with reported IC50 of 0.45 ± 0.06 μM.
- Dihydrochloride salt form for improved solubility in polar solvents.
- Molecular weight 575.64 g/mol and formula C23H32Cl2N6OS3.
- Purity reported as ≥98% by HPLC in supplier and database listings.
- CAS number 217094-32-1 for unambiguous identification.
- Suitable for biochemical and cellular assays targeting cholesterol metabolism.
Medchemexpress LLC K-604 dihydrochloride | 217094-32-1 | 99.4% | 575.64 g·mol⁻1 | C23H32Cl2N6OS3 | 1 ML
K-604 dihydrochloride is a potent, selective acyl-CoA:cholesterol acyltransferase 1 (ACAT-1) inhibitor used in biochemical and cellular research to study cholesterol esterification and related pathways. It is supplied as a 10 mM solution in DMSO or as a solid for preparation of assay stocks and controls.
- Potent, selective ACAT-1 inhibition with low micromolar IC50.
- Suitable for biochemical and cellular assays.
- Available as a 10 mM solution in DMSO and in solid pack sizes.
- High purity for research applications.
- Includes CAS, molecular formula, and molecular weight for identification.
Medchemexpress LLC 2-iminothiolane hydrochloride | 4781-83-3 | MFCD00039013 | 99.9% | 137.63 g/mol | C4H8ClNS | 5 MG
2-Iminothiolane hydrochloride (Traut's reagent) is a thiolating reagent that converts primary amines into sulfhydryl (-SH) groups via amidine formation, enabling modification of proteins, peptides, and glycans for downstream conjugation and crosslinking. It is provided as a high-purity solid with characterized solubility and storage recommendations for biochemical applications.
- Introduces free sulfhydryl groups into primary amines.
- Enables protein, peptide, and glycan conjugation and crosslinking.
- High purity suitable for biochemical assays.
- Soluble in water and DMSO under specified conditions.
- Stable when stored sealed at recommended temperatures.
Medchemexpress LLC SB-399885 hydrochloride | 402713-81-9 | 98.3% | 482.81 g/mol | C18H22Cl3N3O4S | 1 ML
SB-399885 hydrochloride is a research reagent that acts as a selective 5-HT6 (serotonin 6) receptor antagonist. Supplied as the hydrochloride salt, it is suitable for in vitro and in vivo pharmacology studies and is available as solid material or as a ready-to-use 10 mM solution in DMSO.
- Selective 5-HT6 receptor antagonist for research applications.
- Available as solid and as a 10 mM solution in DMSO.
- High purity (98.3%).
- Molecular weight 482.81 g/mol; molecular formula C18H22Cl3N3O4S.
- CAS number 402713-81-9; supplied as the hydrochloride salt.
Medchemexpress LLC Bestatin hydrochloride (Ubenimex hydrochloride) | 65391-42-6 | MFCD00058004 | 99.9% | 100 MG
Bestatin hydrochloride is an inhibitor of CD13 (Aminopeptidase N)/APN and leukotriene A4 hydrolase, used for cancer research. Bestatin hydrochloride is also known to have several biological activities, including:
- Inhibitor of CD13 (aminopeptidase N)/APN and leukotriene A4 hydrolase
- Enhances ATRA-induced differentiation in ATRA-sensitive APL NB4 cells
- Inhibits ATRA-driven phosphorylation of p38 MAPK
- Slows cell cycle progression in D. discoideum
- Inhibits mitosis and inherent multinuclearity in D. discoideum
- Reduces CD13 expression in diabetic mice
- Inhibits MMP-9 specific gelationolytic band densities in diabetic mice
- Inhibits VEGF and heparanase expression in diabetic mice
- Increases splenocytes producing hemolytic anti-SRBC antibodies (at 0.1 mg/kg)
Medchemexpress LLC Niraparib (hydrochloride) | 1038915-64-8 | 99.4% | 356.85 g/mol | C19H21ClN4O | 50 MG
Niraparib hydrochloride is the hydrochloride salt of niraparib, a potent, orally bioavailable inhibitor of poly(ADP-ribose) polymerase 1 and 2 (PARP1/2). It inhibits DNA damage repair and induces apoptosis, making it useful for preclinical studies of DNA repair pathways and anti-tumor activity. Supplied as a solid 50 mg package for research use.
- Potent PARP1 and PARP2 inhibition at nanomolar potency.
- Effective tool for studying DNA damage repair and apoptosis.
- Suitable for in vitro and in vivo preclinical assays.
- Hydrochloride salt form improves handling and solubility.
- Available as a 50 MG solid for small-scale experiments.
Medchemexpress LLC Cp-100356 monohydrochloride | 142715-48-8 | MFCD00911858 | >98.0% | 597.10 g·mol⁻¹ | C31H37ClN4O6 | 1 ML
CP-100356 hydrochloride is a research-grade inhibitor of multidrug transporters used to study transporter-mediated drug disposition and drug-drug interactions. It is supplied in both solid form and as a ready-to-use 10 mM solution in DMSO for in vitro assays, and it is commonly used in pharmacokinetic and cellular uptake studies.
- Potent inhibitor of P-gp and BCRP transporters.
- Available as a 10 mM solution in DMSO or as solid packs (5-100 mg).
- High purity suitable for in vitro assays (>98% by HPLC).
- Well characterized molecular properties for experimental reproducibility.
- Used for transporter assays and drug-drug interaction studies.