Hydrochlorides
![Medchemexpress LLC 5-isoxazoleacetic acid, a-amino-3-chloro-4,5-dihydro-, monohydrochloride, [S-(R*,R*)]- | 161922-40-3 | MFCD32874156 | 99.1% | 215.03 g·mol⁻¹ | C5H8Cl2N2O3 | 25 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000303494.png-250.jpg)
Medchemexpress LLC 5-isoxazoleacetic acid, a-amino-3-chloro-4,5-dihydro-, monohydrochloride, [S-(R*,R*)]- | 161922-40-3 | MFCD32874156 | 99.1% | 215.03 g·mol⁻¹ | C5H8Cl2N2O3 | 25 MG
Acivicin hydrochloride is the hydrochloride salt of acivicin, a natural product γ-glutamyl transpeptidase (GGT) inhibitor used as a biochemical research reagent. It is supplied as a solid and in solution formats for laboratory use, with defined storage conditions to preserve stability and activity.
- High confirmed purity (HPLC): 99.1%.
- Molecular weight 215.03 g·mol⁻¹ and formula C5H8Cl2N2O3.
- Available in mg-scale packs and solution aliquots for assay flexibility.
- Suitable for biochemical studies targeting GGT and related pathways.
- Storage recommendations: 4°C under nitrogen; in solvent -80°C (6 months) or -20°C (1 month).
Medchemexpress LLC 5,7-dimethoxy-3-(4-pyridinyl)quinoline dihydrochloride | 1123491-15-5 | MFCD02262123 | 99.1% | 339.22 g/mol | C16H16Cl2N2O2 | 5 MG
DMPQ dihydrochloride is the dihydrochloride salt of 5,7-dimethoxy-3-(4-pyridinyl)quinoline. It is a small-molecule inhibitor that selectively targets human platelet-derived growth factor receptor β (PDGFRβ) with reported biochemical potency, and is supplied as a light yellow to yellow solid for research use in biochemical and cell-based assays.
- Potent PDGFRβ inhibition with reported IC50 of 80 nM.
- High reported purity suitable for biochemical assays.
- Solid form, convenient for weighing and formulation.
- Available in multiple small pack sizes for research applications.
Medchemexpress LLC Iso-H7 dihydrochloride | 140663-38-3 | MFCD00132899 | 99.1% | 364.29 g/mol | C14H19Cl2N3O2S | 5 MG
Iso-H7 dihydrochloride is a small-molecule protein kinase inhibitor supplied as the dihydrochloride salt for research use. It is intended for biochemical and cell-based studies to modulate kinase activity and is provided in small, high-purity quantities for assay screening and optimization.
- High purity for reliable experimental results.
- Dihydrochloride salt form to aid solubility in polar solvents.
- Available in small milligram pack sizes suitable for screening.
- Validated for use as a protein kinase inhibitor in biochemical and cellular assays.
- Accompanied by datasheet, certificate of analysis, and safety data sheet for quality and safety information.
Medchemexpress LLC L-745870 hydrochloride | 1173023-36-3 | MFCD01529971 | 99.9% | C18H20Cl2N4 | 100 MG
L-745870 hydrochloride is a potent, selective, brain-penetrant, and orally active dopamine D4 receptor antagonist with a Ki of 0.43 nM. It demonstrates weaker affinity for D2 (Ki of 960 nM) and D3 (Ki of 2300 nM) receptors, and exhibits moderate affinity for 5-HT2 receptors, sigma sites, and α-adrenoceptors. This product is intended for research use only.
- Potent, selective, brain-penetrant, and orally active dopamine D4 receptor antagonist
- Weaker affinity for D2 and D3 receptors
- Moderate affinity for 5-HT2 receptors, sigma sites, and α-adrenoceptors
- Good pharmacokinetic properties in rat and monkey
- Excellent brain penetration with high brain to plasma ratios in rats
eMolecules 21987-29-1 | 4,4-Difluoropiperidine | Ambeed | MFCD03094281 | 121.131 | C5H9F2N | 97.000 | FC1(F)CCNCC1 | 25g | 536284494
4,4-Difluoropiperidine | Ambeed | 21987-29-1 | MFCD03094281 | 121.131 | C5H9F2N | 97.000 | FC1(F)CCNCC1 | 25g | 536284494
Medchemexpress LLC Nifenalol hydrochloride | 5704-60-9 | 99.9% | 260.72 g/mol | C11H17ClN2O3 | 10 MG
Nifenalol hydrochloride is a β-adrenergic receptor antagonist used in pharmacological research. It is supplied as a solid and as a pre-made DMSO solution for convenient dosing and assay preparation, and is commonly used in biochemical and electrophysiological studies of β-adrenoceptor activity.
- High purity (99.9%) suitable for biochemical and cellular assays.
- Available in small solid quantities and as 10 mM solutions in DMSO for convenience.
- Supports studies of β-adrenergic receptor antagonism and early afterdepolarization effects.
- Characterized by CAS number 5704-60-9 and standard chemical identifiers.
- Supplied for research use with accompanying datasheet information for handling.
Medchemexpress LLC Prodipine hydrochloride | 31314-39-3 | 99.8% | 315.88 g/mol | C20H26ClN | 5 MG
Prodipine hydrochloride is a diphenyl-phosphonate derivative that acts as a dipeptidyl peptidase IV (DPP-IV) inhibitor. Supplied as the hydrochloride salt for research use, it is intended for enzymology, inhibitor screening, and preclinical biochemical assays; reported IC50 values are ~4.5 μM (purified rabbit DPP-IV) and ~30 μM (rabbit plasma).
- Potent DPP-IV inhibitory activity in vitro.
- Supplied as hydrochloride salt for improved solubility.
- High purity suitable for biochemical assays.
- Available in small milligram pack sizes for screening.
- Characterized with reported IC50 data for assay comparison.
eMolecules 1261471-73-1 | 3-(TRIFLUOROMETHYL)QUINOLIN-7-OL | MFCD18417204 | 1g
Medchem Express | ML337 | 5mg | 784544249 | HY-16636 | 1443118-44-2 | MFCD27937770 | 353.393 | C21H20FNO3
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Medchemexpress LLC N-(1,3-diphenyl-1H-pyrazolo-5-yl)-4-nitrobenzamide | 890764-36-0 | MFCD12546140 | 99.6% | 384.39 g·mol⁻¹ | C22H16N4O3 | 50 MG
VU-29 is a research-grade small molecule that functions as a positive allosteric modulator of the metabotropic glutamate receptor 5 (mGlu5). It is provided as a purified solid for preclinical and in vitro pharmacology studies and assay development.
- Acts as a positive allosteric modulator of mGlu5 receptor.
- Reported EC50 ≈ 9 nM for rat mGlu5 and Ki ≈ 244 nM for the MPEP allosteric site.
- High purity (~99.6%) suitable for analytical and pharmacological assays.
- Molecular formula C22H16N4O3 and molecular weight 384.39 g·mol⁻¹.
- Intended for research use only, not for human or veterinary applications.
- Available in small-scale pack sizes for assay development and screening.
Medchemexpress LLC SKF89976A hydrochloride | 85375-15-1 | 98.7% | 371.90 | C22H26ClNO2 | 25 MG
Hydrochloride salt used as a selective inhibitor of the GABA transporter GAT-1 for in vitro research. It exhibits IC50 values of 0.28 μM (GAT-1), 137.34 μM (GAT-2), and 202.8 μM (GAT-3) in CHO cells, and is supplied as a solid and as a 10 mM solution in DMSO.
Medchemexpress LLC YM-298198 hydrochloride | 1216398-09-2 | MFCD08703122 | 98.0% | 378.92 g/mol | C18H23ClN4OS | 50 MG
YM-298198 hydrochloride is the hydrochloride salt of YM-298198, a selective, orally active, non-competitive antagonist of metabotropic glutamate receptor 1 (mGluR1). Supplied as a solid research-grade reagent, it is used in pharmacology studies and neurological disease models.
- Selective mGluR1 antagonist for receptor pharmacology studies.
- Orally active and non-competitive mechanism of action.
- Supplied as a solid hydrochloride salt for stability and handling.
- Molecular formula C18H23ClN4OS and molecular weight 378.92 g/mol.
- High purity suitable for research applications.
Medchemexpress LLC Benzamide, 4-butoxy-N-(2,4-difluorophenyl)- | 433967-28-3 | C17H17F2NO2 | 25 MG
VU 0357121 is a positive and highly selective mGlu5R allosteric modulator (PAM) with an EC50 of 33 nM. It is inactive or exhibits very weak antagonizing effects at other mGlu receptor subtypes.
- Highly selective mGlu5R allosteric modulator (PAM)
- EC50 of 33 nM
- Inactive or very weakly antagonizing at other mGlu receptor subtypes
- Enhances glutamate sensitivity of mGlu5
- Does not bind at the MPEP allosteric site of mGlu5
- Used for research purposes only
Medchemexpress LLC Numidargistat dihydrochloride | 98.5% | 360.04 g·mol^-1 | C11H24BCl2N3O5 | 100 MG
Numidargistat dihydrochloride is a research-grade small-molecule inhibitor of arginase used in preclinical immunology and oncology studies. It displays nanomolar activity against recombinant human arginase enzymes and is supplied as the dihydrochloride salt with manufacturer guidance for storage and batch-specific purity.
- Potent inhibition of arginase 1 and 2 (IC50 ≈ 86 nM and 296 nM)
- Orally bioavailable profile suitable for in vivo dosing in preclinical models
- Suitable for in vitro biochemical and cell-based assays
- Dihydrochloride salt form improves solubility and handling
- Supplied with batch COA and storage recommendations for research use only
![eMolecules 35478-79-6 | [1,3]Dioxolo[4,5-g]quinolin-8-ol | J & W PharmLab LLC | MFCD22395081 | 189.170 | C10H7NO3 | 95.000 | Oc1ccnc2cc3OCOc3cc12 | 1g | 456105793](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502147440.JPG-250.jpg)
eMolecules 35478-79-6 | [1,3]Dioxolo[4,5-g]quinolin-8-ol | J & W PharmLab LLC | MFCD22395081 | 189.170 | C10H7NO3 | 95.000 | Oc1ccnc2cc3OCOc3cc12 | 1g | 456105793
[1,3]Dioxolo[4,5-g]quinolin-8-ol | J & W PharmLab LLC | 35478-79-6 | MFCD22395081 | 189.170 | C10H7NO3 | 95.000 | Oc1ccnc2cc3OCOc3cc12 | 1g | 456105793
Medchemexpress LLC 2-(benzofuran-2-yl)-2-imidazoline hydrochloride | 89196-95-2 | MFCD00672666 | 99.8% | 222.67 g·mol⁻¹ | C11H11ClN2O | 100 MG
RX 801077 hydrochloride is a research chemical that functions as a selective imidazoline I2 receptor (I2R) agonist used in preclinical studies of inflammation and neuroprotection. It is supplied as the hydrochloride salt in small solid quantities or as DMSO solutions for biological assays.
- Selective imidazoline I2 receptor agonist (Ki ≈ 70.1 nM).
- High purity (99.8%) for reliable experimental results.
- Molecular weight 222.67 g·mol⁻¹ and CAS 89196-95-2 for unambiguous identification.
- Available as solid and 10 mM DMSO solution formats for assay preparation.
- Supplied in small research quantities suitable for in vitro studies.