Hydrochlorides
![Medchemexpress LLC N-[3-oxo-3-[4-(4-pyridinyl)-1-piperazinyl]propyl]-2,1,3-benzothiadiazole-4-sulfonamide | 1135243-19-4 | MFCD18086889 | 99.8% | 432.52 g/mol | C18H20N6O3S2 | 25 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000244005.png-250.jpg)
Medchemexpress LLC N-[3-oxo-3-[4-(4-pyridinyl)-1-piperazinyl]propyl]-2,1,3-benzothiadiazole-4-sulfonamide | 1135243-19-4 | MFCD18086889 | 99.8% | 432.52 g/mol | C18H20N6O3S2 | 25 MG
VU 0255035 is a selective, competitive antagonist of the M1 muscarinic acetylcholine receptor used as a research compound for central nervous system studies, including seizure models and investigations of neuronal excitability. It is supplied with high purity and is available in solid and solution formats for in vitro and in vivo experiments.
- Selective M1 antagonist with reported nanomolar activity.
- Brain-penetrant compound suitable for in vivo CNS studies.
- High supplied purity (≈99.8%).
- Molecular weight 432.52 g/mol (C18H20N6O3S2).
- Available in multiple pack sizes and DMSO solution formats for easy dosing.
Selleck Chemical LLC Serotonin creatinine sulfate monohydrate S3344-25mg
Serotonin (5-Hydroxytryptamine) creatinine sulfate monohydrate is an active endogenous metabolite
Medchemexpress LLC Urapidil hydrochloride | 64887-14-5 | 99.9% | 1 ML
Urapidil hydrochloride is an orally active α1-adrenoceptor antagonist and 5-HT1A receptor agonist with blood-brain barrier permeability. It exhibits pIC50 values of 6.13 against α1-adrenoceptor and 4.38 against α2-adrenoceptor, and demonstrates an antihypertensive effect.
- Orally active α1-adrenoceptor antagonist
- 5-HT1A receptor agonist
- Blood-brain barrier permeability
- Exhibits antihypertensive effect
- pIC50 of 6.13 against α1-adrenoceptor
- pIC50 of 4.38 against α2-adrenoceptor
Sigma Aldrich Fine Chemicals Biosciences 3-Pyridylacetic acid hydrochloride 98% | 6419-36-9 | MFCD00012819 | 1G
3-Pyridylacetic acid hydrochloride 98% | Purity: 98% | Mol Wt: 173.6 | 6419-36-9 | MFCD00012819 | 1G
Medchemexpress LLC DANP dihydrochloride | 99.3% | 50 MG
DANP dihydrochloride is a bulge base recognition probe that strongly and specifically binds to the single cytosine and thymine bulges. It can stabilize both single cytosine and thymine bulges in duplex DNA.
- Bulge base recognition probe
- Strongly and specifically binds to single cytosine and thymine bulges
- Can stabilize both single cytosine and thymine bulges in duplex DNA
Medchemexpress LLC Pazopanib hydrochloride | 635702-64-6 | 100.0% | 100MG
Pazopanib hydrochloride | 635702-64-6 | 100.0% | 100MG
Apexbio Technology LLC Dapoxetine HCl 129938-20-1 25mg
Dapoxetine hydrochloride (CAS 129938-20-1) is a short-acting selective serotonin reuptake inhibitor (SSRI) It exerts its pharmacological effect by inhibiting the reuptake of serotonin (5-HT) at the presynaptic membrane thereby increasing serotonin activity in the synaptic cleft This modulation of serotonergic neurotransmission has been shown to delay ejaculation latency making dapoxetine hydrochloride an established model compound for investigating serotonergic regulation of ejaculatory control It is widely used in research on the neurobiology and therapeutic approaches to premature ejaculation and related disorders
Medchemexpress LLC IACS-9571 hydrochloride | 2319611-93-1 | 98.3% | 679.22 g/mol | C32H43ClN4O8S | 10 MG
IACS-9571 hydrochloride is a selective, low-nanomolar inhibitor of the TRIM24 and BRPF1 bromodomains used as a research tool to probe bromodomain biology and epigenetic regulation. It is supplied as the hydrochloride salt and is characterized by low-nanomolar binding (IC50 ≈ 8 nM for TRIM24; Kd values in the low nanomolar range for TRIM24 and BRPF1).
- Selective dual TRIM24/BRPF1 bromodomain inhibition
- Low-nanomolar potency (IC50 ≈ 8 nM)
- High purity suitable for research (~98.3%)
- Available in small research pack sizes for in vitro work
- Offered as solid and as 10 mM solutions in DMSO
Medchemexpress LLC Nilotinib hydrochloride dihydrate | 00-00-0 | 99.9% | 602.01 g/mol | C28H27ClF3N7O3 | 25 MG
Nilotinib hydrochloride dihydrate is the dihydrate hydrochloride salt of nilotinib, a potent, orally active Bcr-Abl tyrosine kinase inhibitor used in research to study chronic myelogenous leukemia (CML) and Bcr-Abl-driven signaling. It is supplied as a solid research reagent with high purity and documented solubility and storage recommendations to support assay preparation and long-term stability.
- High purity suitable for analytical and biological studies.
- Potent Bcr-Abl tyrosine kinase inhibitor for CML research.
- Solid form with recommended sealed storage away from moisture.
- Soluble in DMSO at 100 mg/mL for assay preparation.
- Documented stability in solution and long-term storage conditions.
AdipoGen Terbinafine hydrochloride
Chemical. CAS 78628-80-5. Formula C21H25N . HCl. MW 291.4 . 36.5. Synthetic. Terbinafine is an antifungal and antimycotic compound that is highly active against dermatophytes, mold, other basic fungi, and some strains of yeast. It is clinically used to treat nail and skin infections. Inhibits ergosterol synthesis, essential component of fungal cell membranes. Potent non-competitive inhibitor at the stage of squalene epoxidation IC50=30nM for C. albicans. Selective activator of the K2P channel TASK3 pEC50 = 6.2. Exhibits >10-fold selectivity for TASK3 over TREK2, TRESK, THIK1 and TASK2. Also inhibits TWIK1 pIC50 = 5.69. K2P channels might also be a target for ist antifungal activity. Shown to exhibit at higher concentrations anti-tumor and anti-angiogenic activity by inducing cell cycle arrest, and to display interesting anti-inflammatory and free radical scavenging activities.
Medchemexpress LLC 1-(4,4-diphenyl-3-butenyl)-3-piperidinecarboxylic acid hydrochloride | 85375-15-1 | MFCD01321071 | >98.0% | 371.91 | C22H26ClNO2 | 10 MG
Selective GABA transporter 1 (GAT-1) inhibitor supplied as the hydrochloride salt for neuroscience research. It blocks GABA reuptake, is brain-penetrant, and is commonly used to probe GABAergic signaling and transporter pharmacology in vitro and in vivo.
- Selective GAT-1 inhibitor that blocks GABA reuptake.
- Brain-penetrant, suitable for in vivo studies.
- High purity (≥98% by HPLC) for reliable experimental results.
- Hydrochloride salt form for improved solubility in biological assays.
- Available as solid and as solution formats for flexible use.
- Commonly used to study GABA uptake and transporter pharmacology.
Medchemexpress LLC Erlotinib hydrochloride | 183319-69-9 | 99.7% | 25 MG
Erlotinib hydrochloride analytical standard, the hydrochloride salt of erlotinib, provided as a high-purity solid for use as a reference material in biochemical and analytical assays.
- Analytical standard for erlotinib hydrochloride.
- Purity 99.73% (analytical).
- Molecular weight 429.90 g/mol.
- Chemical formula C22H24ClN3O4.
- Appearance: white to off-white solid.
- Available sizes: 5 mg, 10 mg, 25 mg, 50 mg, 100 mg; 200 mg and 500 mg available by quote.
- Store under conditions specified on the certificate of analysis.
Medchemexpress LLC DRP1i27 dihydrochloride | C20H28Cl2N6O | 5 MG
DRP1i27 dihydrochloride is a potent inhibitor of human Drp1 (dynamin-related protein 1). It binds to the GTPase site of Drp1, forming hydrogen bonds with Gln34 and Asp218. This compound targets Drp1-mediated mitochondrial fission in cell line models and offers protection against simulated ischemia-reperfusion injury.
- Directly binds to and inhibits the GTPase activity of human Drp1
- Increases cellular networks of mitochondria in human and mouse fibroblasts
- Protective effects against simulated ischemia-reperfusion injury
Medchemexpress LLC Ecopipam (hydrochloride) | 190133-94-9 | 99.5% | 350.28 | 1 ML
Ecopipam hydrochloride is a potent and selective antagonist of dopamine D1/D5 receptors. It demonstrates significant selectivity over D2, D4, 5-HT, and α2a receptors. This compound is suitable for research into conditions such as schizophrenia and obesity.
- Potent and selective dopamine D1/D5 receptor antagonist
- Exhibits over 40-fold selectivity for D1/D5 over D2, D4, 5-HT, and α2a receptors
- Suitable for research applications in schizophrenia and obesity
- High purity of 99.46%
- Appears as a white to off-white solid
Medchemexpress LLC Doxepin impurity 1 (hydrochloride) | 4504-96-5 | 25mg
Doxepin impurity 1 hydrochloride is an impurity of Doxepin (HY-B0725A)