Hydrochlorides
Medchemexpress LLC Dasatinib hydrochloride | 854001-07-3 | MFCD00713745 | 99.3% | 524.5 g/mol | C22H27Cl2N7O2S | 50 MG
Dasatinib hydrochloride is the hydrochloride salt of dasatinib, a potent ATP-competitive dual Src/Bcr-Abl kinase inhibitor supplied as a purified solid for research and analytical applications. It is intended for in vitro studies and signal transduction research; not for human or clinical use.
- High purity (99.3%).
- Suitable for research and analytical applications.
- Molecular formula C22H27Cl2N7O2S; molecular weight 524.5 g/mol.
- Registered CAS number 854001-07-3 for unambiguous identification.
- Available in small milligram pack sizes for laboratory use.
Medchemexpress LLC GR 55562 hydrochloride | 172854-55-6 | 98.0% | 411.92 | 10 MG
GR 55562 hydrochloride is a selective 5-HT1B receptor antagonist. It can be used for the research of nerve disease. This product is for research use only and not sold to patients.
- Selective 5-HT1B receptor antagonist.
- Applicable for research on nerve disease.
![Medchemexpress LLC 1-Propanamine, 3-dibenz[b,e]oxepin-11(6H)-ylidene-N-methyl-, hydrochloride (1:1), (3E)- | 4504-96-5 | MFCD00135797 | 10mg](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000267001.png-250.jpg)
Medchemexpress LLC 1-Propanamine, 3-dibenz[b,e]oxepin-11(6H)-ylidene-N-methyl-, hydrochloride (1:1), (3E)- | 4504-96-5 | MFCD00135797 | 10mg
Doxepin impurity 1 hydrochloride is an impurity of Doxepin (HY-B0725A)
Medchemexpress LLC Racemic anabasine | 13078-04-1 | 162.24 g/mol | C10H14N2 | 100 MG
(±) Anabasine is the racemic form of anabasine, an alkaloid that acts as an agonist of the α7 nicotinic acetylcholine receptor and has reported anti-inflammatory and insecticidal activities. See manufacturer datasheet for solubility, storage, and handling details.
- Racemic form of anabasine
- Agonist of α7 nicotinic acetylcholine receptor
- Exhibits anti-inflammatory and insecticidal activities
- CAS number 13078-04-1
- Molecular formula C10H14N2; molecular weight 162.24 g/mol
- Solubility: in vitro DMSO 130 mg/mL; in vivo formulations ≥ 2.17 mg/mL (clear solutions)
- Storage: pure form -20°C (3 years); 4°C (2 years)
Medchemexpress LLC TAK-960 dihydrochloride | C27H36Cl2F3N7O3 | 100 MG
TAK-960 dihydrochloride is a potent, orally available, and selective inhibitor of polo-like kinase 1 (PLK1), demonstrating an IC50 of 0.8 nM. It also displays inhibitory effects on PLK2 and PLK3 with IC50 values of 16.9 nM and 50.2 nM, respectively. This compound has been shown to effectively inhibit the proliferation of various cancer cell lines and exhibits significant efficacy against multiple tumor xenografts in preclinical studies.
- Potent and selective PLK1 inhibitor (IC50 = 0.8 nM)
- Inhibits PLK2 and PLK3
- Induces G2/M cell cycle arrest in HeLa cells
- Inhibits proliferation across multiple cancer cell lines
- Exhibits significant efficacy against tumor xenografts
- Demonstrates substantial antitumor activity and good tolerability in animal models
Medchemexpress LLC ZM323881 hydrochloride | 193000-39-4 | C22H19ClFN3O2 | 1 ML
ZM323881 hydrochloride is a potent and selective inhibitor of Vascular Endothelial Growth Factor Receptor 2 (VEGFR2) with an IC50 of less than 2 nM. This anilinoquinazoline specifically targets VEGFR2 tyrosine kinase activity, demonstrating excellent selectivity over other receptor tyrosine kinases.
- Potent and selective VEGFR2 inhibitor
- High purity (99.63%)
- Specifically targets VEGFR2 tyrosine kinase activity
- Exhibits excellent selectivity over other receptor tyrosine kinases
- Inhibits VEGF-A-induced endothelial cell proliferation
- Inhibits VEGFR2 tyrosine phosphorylation
- Molecular Weight: 411.86
- Formula: C22H19ClFN3O2
- Appearance: Solid, light yellow to yellow
Medchemexpress LLC CP 93129 dihydrochloride | 879089-64-2 | 99.0% | 288.17 g·mol⁻1 | C12H15Cl2N3O | 1 MG
CP 93129 dihydrochloride is a selective 5-HT1B receptor agonist supplied for research use. It is used in pharmacology and neuroscience studies, including investigations related to Parkinson's disease, and is provided as a high-purity solid suitable for analytical, in vitro, and in vivo applications.
- Selective 5-HT1B receptor agonist suitable for receptor pharmacology studies.
- High purity (99.0%) for consistent experimental results.
- Molecular weight 288.17 g·mol⁻1 and formula C12H15Cl2N3O for precise calculations.
- Off-white to light yellow solid for convenient handling and storage.
- Recommended storage at 4°C, sealed and protected from moisture and light.
- Available in small, accurately weighed milligram quantities for dosing and assays.
Apexbio Technology LLC Tirofiban hydrochloride monohydrate 150915-40-5 5mg
Tirofiban hydrochloride monohydrate (CAS 150915-40-5) is a small-molecule inhibitor targeting platelet glycoprotein IIb/IIIa receptors It is designed to reversibly antagonize the binding of fibrinogen to these receptors thereby inhibiting platelet aggregation and thrombus formation Tirofiban hydrochloride monohydrate exerts its biological activity primarily through selective reversible inhibition of glycoprotein IIb/IIIa-mediated platelet aggregation Based on these pharmacological properties tirofiban hydrochloride monohydrate holds research potential in antithrombotic therapy and the investigation of unstable angina and thrombus-associated cardiovascular conditions
eMolecules 3651-67-0 | N-Methylmorpholine hydrochloride | Combi-Blocks | MFCD00039042 | 137.610 | C5H12ClNO | 96.000 | Cl.CN1CCOCC1 | 1g | 303362220
N-Methylmorpholine hydrochloride | Combi-Blocks | 3651-67-0 | MFCD00039042 | 137.610 | C5H12ClNO | 96.000 | Cl.CN1CCOCC1 | 1g | 303362220
Medchemexpress LLC Tak-960 dihydrochloride | 2320307-83-1 | C27H36Cl2F3N7O3 | 10 MM 1 ML
TAK-960 dihydrochloride is an orally available, selective inhibitor of polo-like kinase 1 (PLK1) with an IC50 of 0.8 nM. It also shows inhibitory activities against PLK2 and PLK3, with IC50s of 16.9 nM and 50.2 nM, respectively. This compound inhibits the proliferation of multiple cancer cell lines and demonstrates significant efficacy against various tumor xenografts.
- Acts as a selective inhibitor of polo-like kinase 1 (PLK1)
- Shows inhibitory activities against PLK2 and PLK3
- Causes accumulation of G2-M cells
- Leads to aberrant polo mitosis morphology
- Increases phosphorylation of histone H3 (pHH3)
- Induces G2/M cell cycle arrest in HeLa cells without significant cytotoxicity
- Inhibits proliferation of multiple cancer cell lines
- Exhibits significant efficacy against multiple tumor xenografts
eMolecules 53179-07-0 | Medchem Express | Nisoxetine | 5mg | 783660599 | HY-B1704 | MFCD00865443 | 271.36 | C17H21NO2
Medchem Express | Nisoxetine | 5mg | 783660599 | HY-B1704 | 53179-07-0 | MFCD00865443 | 271.360 | C17H21NO2
Medchemexpress LLC Nifenalol hydrochloride | 5704-60-9 | 99.9% | 260.72 g/mol | C11H17ClN2O3 | 100 MG
Nifenalol hydrochloride is a research-grade β-adrenergic receptor antagonist (hydrochloride salt) used in pharmacology and cardiac electrophysiology studies. It is provided as a high-purity solid for biochemical and cellular assays, with recommended storage and solvent stability guidance supplied by the manufacturer.
- Chemical identity: CAS number 5704-60-9; formula C11H17ClN2O3; molecular weight 260.72 g/mol.
- Primary activity: β-adrenergic receptor antagonist demonstrating early afterdepolarization effects.
- High purity: 99.9% as listed by manufacturer.
- Available formats: solid and solution stocks, sold in multiple sizes including 100 MG.
- Storage recommendation: sealed, away from moisture and light; solids refrigerated at 4°C; in solvent store at -80°C (6 months) or -20°C (1 month).
Apexbio Technology LLC Terbinafine HCl 78628-80-5 100mg
Terbinafine hydrochloride (CAS 78628-80-5) is a small-molecule inhibitor targeting squalene epoxidase It is designed to selectively inhibit this key enzyme within the fungal sterol biosynthesis pathway thereby disrupting cell membrane integrity Terbinafine hydrochloride exerts its biological activity primarily through non-competitive inhibition of squalene epoxidase In experimental studies Terbinafine hydrochloride demonstrates potent antifungal activity with reported IC50 values against fungal squalene epoxidase in the nanomolar range Based on these pharmacological properties Terbinafine hydrochloride holds research potential in antifungal drug mechanism studies fungal sterol metabolism and therapeutic strategies against fungal pathogens in experimental models
Medchemexpress LLC RS-127445 | 199864-87-4 | C17H16FN3 | 1 ML
RS-127445 is a selective, high affinity, and orally bioavailable 5-HT2B receptor antagonist. It demonstrates a pKi of 9.5 and exhibits over 1000-fold selectivity for this receptor compared to numerous other receptor and ion channel binding sites.
- Selective 5-HT2B receptor antagonist
- High affinity (pKi of 9.5)
- Orally bioavailable
- Over 1000-fold selectivity compared to other receptors
- Potently blocks 5-HT evoked increases in intracellular calcium concentrations
Medchemexpress LLC Y-33075 dihydrochloride | 173897-44-4 | 98.8% | 353.25 | 50 MG
Y-33075 dihydrochloride is a selective ROCK inhibitor with an IC50 of 3.6 nM. It also inhibits PKC and CaMKII, and has shown effects in extending neurites in retinal ganglion cells and lowering intraocular pressure.
- Potent and selective ROCK inhibitor
- Inhibits PKC and CaMKII
- Extends neurites in retinal ganglion cells
- Lowers intraocular pressure
- Increases regenerating axons