Hydrochlorides
Medchemexpress LLC TG 100572 hydrochloride | 867331-64-4 | MFCD18251422 | 98.8% | 512.43 g/mol | C26H27Cl2N5O2 | 50 MG
TG 100572 Hydrochloride is a multi-targeted kinase inhibitor supplied as a hydrochloride salt for laboratory research. It inhibits several receptor tyrosine kinases and Src family kinases and is used in vitro to study signaling pathways and kinase-dependent cellular processes. Offered in multiple pack sizes with high listed purity for biochemical and cell-based studies.
- Multi-targeted kinase inhibition profile (VEGFR, FGFR, PDGFR, Src family).
- High listed purity suitable for in vitro assays.
- Available in small pack sizes and solution format for flexibility.
- Compatible with biochemical and cell-based assay workflows.
- For research use only; not for human or veterinary use.
Medchemexpress LLC Nisoxetine | 53179-07-0 | 98.6% | 100 MG
Nisoxetine is a potent and selective inhibitor of noradrenaline transporter (NET), with a Kd of 0.76 nM. It functions as an antidepressant and local anesthetic, capable of blocking voltage-gated sodium channels. This product is intended for research use only.
- Potently and selectively inhibits the noradrenaline transporter (NET) with a Kd of 0.76 nM.
- Acts as both an antidepressant and a local anesthetic.
- Can block voltage-gated sodium channels.
- Available in multiple quantities.
- Comes with a data sheet, COA, SDS, and handling instructions.
- Detailed solubility information provided for in vitro use.
Medchemexpress LLC Angoline hydrochloride | 21080-31-9 | 5 MG
Angoline hydrochloride is a potent and selective IL6/STAT3 signaling pathway inhibitor with an IC50 of 11.56 μM. Angoline hydrochloride inhibits STAT3 phosphorylation and its target gene expression, and inhibits cancer cell proliferation.
- Potent and selective IL6/STAT3 signaling pathway inhibitor
- IC50 of 11.56 μM
- Inhibits STAT3 phosphorylation
- Inhibits its target gene expression
- Inhibits cancer cell proliferation
- Purity: >98%
eMolecules 28356-58-3 | 4-Pyridineacetic acid | Combi-Blocks | MFCD03701446 | 137.138 | C7H7NO2 | 98.000 | OC(=O)Cc1ccncc1 | 1g | 357561050
4-Pyridineacetic acid | Combi-Blocks | 28356-58-3 | MFCD03701446 | 137.138 | C7H7NO2 | 98.000 | OC(=O)Cc1ccncc1 | 1g | 357561050
Medchemexpress LLC N,N'-bis(2-hydroxybenzyl)ethylenediamine-N,N'-diacetic acid dihydrochloride | 35369-53-0 | MFCD04113603 | >95.0% | 461.34 | C20H26Cl2N2O6 | 1 ML
HBED dihydrochloride is an orally active, hexadentate phenolic aminocarboxylate iron chelator (N,N'-bis(2-hydroxybenzyl)ethylenediamine-N,N'-diacetic acid dihydrochloride) supplied for research use in solution and solid formats for studies of iron binding and chelation biology.
- Orally active hexadentate iron chelator.
- Suitable for iron chelation research and biochemical assays.
- Supplied as ready-to-use 10 mM in DMSO solution and as solid material.
- Solid sizes available: 100 mg, 250 mg, 500 mg, 1 g.
- Molecular weight 461.34; formula C20H26Cl2N2O6.
- Typical purity specification ≥95.0% (batch dependent).
Medchemexpress LLC T-3775440 hydrochloride | 1422535-52-1 | 99.1% | 346.85 g/mol | C18H23ClN4O | 5 MG
T-3775440 hydrochloride is a small-molecule, irreversible inhibitor of lysine-specific histone demethylase 1 (KDM1/LSD1) used in biochemical and cellular research. It is supplied as a light yellow to yellow solid with high purity and characterized solubility and storage recommendations.
- Irreversible KDM1/LSD1 inhibitor; IC50 = 2.1 nM.
- Molecular formula C18H23ClN4O; molecular weight 346.85 g/mol.
- Purity approximately 99.1% by HPLC.
- Physical state: light yellow to yellow solid.
- Solubility: DMSO ≥ 30.18 mg/mL; water 8.33 mg/mL with ultrasonic warming to 60°C.
- Storage: powder at 4°C under inert atmosphere; solutions: -80°C (6 months), -20°C (1 month).
- Supplied as a 5 mg quantity.
![Medchemexpress LLC N'-[[2-(2,3-dichlorophenoxy)phenyl]methyl]-N,N'-dimethylethane-1,2-diamine | 2289726-31-2 | >98.0% | 375.72 g/mol | C17H21Cl3N2O | 10 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000288707.png-250.jpg)
Medchemexpress LLC N'-[[2-(2,3-dichlorophenoxy)phenyl]methyl]-N,N'-dimethylethane-1,2-diamine | 2289726-31-2 | >98.0% | 375.72 g/mol | C17H21Cl3N2O | 10 MG
DCPT1061 hydrochloride is a research-use small-molecule inhibitor of protein arginine methyltransferases, reported to inhibit PRMT1, PRMT6, and PRMT8. Supplied as the hydrochloride salt to improve handling and solubility, it is provided in small milligram quantities for laboratory use. Typical distributor-reported specifications include a molecular weight of 375.72 g/mol, formula C17H21Cl3N2O, and reported purity greater than 98%. Store sealed at -20°C and prepare solutions in DMSO as required.
- Reported inhibitor of PRMT1, PRMT6, and PRMT8.
- Supplied as the hydrochloride salt for improved solubility and handling.
- Molecular weight 375.72 g/mol and formula C17H21Cl3N2O.
- Purity reported greater than 98% by distributors.
- Soluble in DMSO (~50 mg/mL) with warming or sonication.
- For research use only; not for human or clinical use.
Medchemexpress LLC T-3775440 hydrochloride | 1422535-52-1 | 99.1% | 346.85 g/mol | C18H23ClN4O | 1 ML
T-3775440 hydrochloride is an irreversible lysine-specific histone demethylase 1 (LSD1) inhibitor used in biochemical and cellular research to probe epigenetic regulation. The hydrochloride salt is provided as a concentrated solution for in vitro applications.
- Irreversible LSD1 inhibitor with IC50 2.1 nM.
- High purity (99.1%) suitable for research use.
- Molecular weight 346.85 g/mol; formula C18H23ClN4O.
- Supplied as 10 mM solution in DMSO, 1 mL vial.
- Soluble in DMSO (≥ 30.18 mg/mL) and soluble in water with ultrasonic/warming.
- Storage recommendations: in solvent, -80°C for up to 6 months or -20°C for 1 month.
Medchemexpress LLC H3B-6545 hydrochloride | 2052132-51-9 | 99.2% | 604.04 | 1 ML
H3B-6545 hydrochloride | 2052132-51-9 | 99.2% | 604.04 | 1 ML
Medchemexpress LLC TAS-103 dihydrochloride | 174634-09-4 | 98.5% | 406.31 | 50 MG
TAS-103 dihydrochloride is a dual inhibitor of DNA topoisomerase I/II, used for cancer research.
- Dual inhibitor of DNA topoisomerase I/II.
- Active on CCRF-CEM cells with an IC50 value of 5 nM.
- Significantly increases levels of topo IIα FITC immunofluorescence in individual CCRF-CEM cells.
- Highly cytotoxic to Lewis lung carcinoma (LLC) cells.
- Inhibits the viability of HeLa cells with an IC50 of 40 nM.
- Disrupts signal recognition particle (SRP) complex formation and induces destabilization of SRP14 and SRP19.
- Causes significant tumor growth suppression in mice bearing Lewis lung carcinoma (LLC) cells without obvious body weight loss.
- Liposomal TAS-103 is more active than free TAS-103 in vivo.
Medchemexpress LLC Azepexole (hydrochloride) | 147663-20-5 | MFCD35200177 | >98.0% | 217.7 g/mol | C9H16ClN3O | 5 MG
Azepexole hydrochloride is the hydrochloride salt of azepexole (B-HT 933), a selective α2-adrenoceptor agonist used as a research reagent to study adrenergic receptor pharmacology and related physiological effects such as analgesia and antitussive responses.
- Selective α2-adrenoceptor agonist used in receptor pharmacology studies.
- Reported purity greater than 98% (HPLC).
- Molecular formula C9H16ClN3O and molecular weight 217.7 g/mol.
- Provided as a small-scale research pack suitable for laboratory experiments.
- Intended for research use only; not for human or clinical use.
Medchemexpress LLC Bestatin hydrochloride | 65391-42-6 | 99.9% | 1 ML
Bestatin hydrochloride is an inhibitor of CD13 (Aminopeptidase N)/APN and leukotriene A4 hydrolase, primarily employed in cancer research. It demonstrates significant effects on cell differentiation, proliferation, and enzymatic activities both in vitro and in vivo.
- Inhibits CD13 (Aminopeptidase N)/APN and leukotriene A4 hydrolase.
- Enhances ATRA-induced differentiation in ATRA-sensitive APL NB4 cells.
- Inhibits ATRA-driven phosphorylation of p38 MAPK.
- Slows cell cycle progression, reduces cell growth, and decreases cell division frequency.
- Significantly reduces CD13 expression in diabetic mice.
- Inhibits expression of VEGF and heparanase in diabetic mice.
- Increases the number of splenocytes producing hemolytic anti-SRBC antibodies in vivo.
Medchemexpress LLC 1,3-propanediol, 2-amino-2-(1-nonyl-1H-1,2,3-triazol-4-yl) hydrochloride | 2376132-24-8 | 99.9% | 320.86 | C14H29ClN4O2 | 10 MG
KARI 201 hydrochloride is a dual-action small-molecule research compound that functions as a selective, brain-penetrant acid sphingomyelinase (ASM) inhibitor and a ghrelin receptor (GHSR) agonist. It is intended for preclinical in vitro and in vivo studies and is supplied as a solid for laboratory research use only.
- Selective acid sphingomyelinase inhibitor.
- Ghrelin receptor agonist with brain penetration.
- High purity, 99.9% (HPLC).
- Molecular weight 320.86 g·mol-1.
- Supplied as a 10 mg solid; store sealed at -20°C.
- For research use only; not for human or diagnostic use.
Medchemexpress LLC preQ1 dihydrochlorid 25mg | 86694-45-3 | 252.10 g/mol | C7H11Cl2N5O | 25 MG
preQ1 dihydrochloride is the dihydrochloride salt of pre-queuosine1, a guanine-derived nucleobase and a direct precursor in queuine biosynthesis. It is supplied for research use as a biochemical probe that binds with high affinity to the PreQ1 riboswitch aptamer and is suitable for studies of tRNA modification and riboswitch function.
- High purity suitable for research use (98.88%).
- Solid, white to light brown appearance for easy handling.
- Soluble in DMSO (125 mg/mL) and water (14.29 mg/mL) with sonication or warming.
- Direct precursor in queuine biosynthesis and riboswitch-binding probe.
- Stable when stored sealed away from moisture and light; in solvent -80°C (6 months), -20°C (1 month).
Medchemexpress LLC SB-258585 hydrochloride | 1216468-02-8 | 99.7% | 523.82 g/mol | C18H23ClIN3O3S | 25 MG
SB-258585 hydrochloride is a research-grade small molecule that binds with high affinity to the 5-HT6 (serotonin 6) receptor and is commonly used in receptor labeling and pharmacological studies.
- High affinity for the 5-HT6 receptor.
- Useful for labeling recombinant and native 5-HT6 receptors.
- High reported purity (about 99.7%).
- Provided as the hydrochloride salt for improved stability.
- Available in small research pack sizes, suitable for laboratory assays.