Hydrochlorides
Medchemexpress LLC Iso-H7 dihydrochloride | 140663-38-3 | 99.1% | 364.29 | 25 MG
Iso-H7 dihydrochloride is an inhibitor of protein kinase with IC50 values of 22 and 34 μM for PKC and PKA, respectively. It has a negative control effect on PKA in satellite cell myogenesis.
- Protein kinase inhibitor.
- Inhibits PKC (IC50 = 22 μM).
- Inhibits PKA (IC50 = 34 μM).
- Negative control of PKA on satellite cell myogenesis.
Medchemexpress LLC Co 101244 (hydrochloride) | 193356-17-1 | 99.9% | 377.90 g/mol | C21H28ClNO3 | 25 MG
Co 101244 hydrochloride is the hydrochloride salt of a selective NR2B-containing NMDA receptor antagonist used in pharmacology and neuroscience research. It is supplied as a solid with high purity and is accompanied by supporting documentation for safe handling and experimental use.
- High purity: 99.9%.
- Molecular weight 377.90 g/mol.
- Chemical formula C21H28ClNO3.
- Appearance solid, light yellow to yellow.
- Storage recommendations: store sealed and away from moisture; in solvent, -80°C for up to 6 months, -20°C for up to 1 month.
- Includes datasheet and safety data sheet for handling and hazard information.
- Intended for research use only; not for human or veterinary use.
Medchemexpress LLC SKF89976A hydrochloride | 85375-15-1 | 98.7% | 371.90 | C22H26ClNO2 | 25 MG
Hydrochloride salt used as a selective inhibitor of the GABA transporter GAT-1 for in vitro research. It exhibits IC50 values of 0.28 μM (GAT-1), 137.34 μM (GAT-2), and 202.8 μM (GAT-3) in CHO cells, and is supplied as a solid and as a 10 mM solution in DMSO.
Apexbio Technology LLC Duloxetine HCl 136434-34-9 10mg
Duloxetine hydrochloride (CAS 136434-34-9) is a small molecule compound classified as a selective inhibitor of serotonin and norepinephrine reuptake By blocking the reabsorption of these neurotransmitters at the synaptic cleft duloxetine modulates serotonergic and noradrenergic signaling within the central nervous system This pharmacological action has rendered it a valuable tool in research models investigating neurochemical pathways involved in mood regulation pain perception and stress response Duloxetine HCl is commonly utilized in studies of depression anxiety and chronic pain to elucidate monoaminergic mechanisms and to evaluate therapeutic strategies targeting neurotransmitter reuptake
Medchemexpress LLC CGP 78608 hydrochlor 1mg | 1135278-54-4 | 1MG
CGP 78608 hydrochloride is a highly potent and selective antagonist at the glycine-binding site of the NMDA receptor with an IC50 of 6 nM CGP 78608 hydrochloride acts as a potentiator of GluN1/GluN3A-mediated glycine currents with an estimated EC50 in the low nM range (26 3 nM) Anticonvulsant activity[1 [2
Medchemexpress LLC Zt 52656a hydrochloride | 115730-24-0 | MFCD00673899 | 100.0% | 390.87 g/mol | C19H26ClF3N2O | 25 MG
ZT 52656A hydrochloride is a selective kappa-opioid receptor agonist supplied as the hydrochloride salt for preclinical and in vitro research, including studies of ocular pain. The compound is for research use only and is not intended for human therapeutic use.
- Selective kappa-opioid receptor agonist.
- Provided as the hydrochloride salt.
- High purity (99.98%).
- Molecular weight 390.87 g/mol.
- Chemical formula C19H26ClF3N2O.
- Appearance: solid, white to off-white.
- Available in small research sizes, e.g., 25 MG.
- Intended for preclinical and in vitro research use only.
eMolecules 1402576-61-7 | 7-(TRIFLUOROMETHYL)QUINOLIN-3-AMINE | AstaTech | MFCD28133454 | 212.175 | C10H7F3N2 | 95.000 | Nc1cnc2cc(ccc2c1)C(F)(F)F | 1g | 261435877
7-(TRIFLUOROMETHYL)QUINOLIN-3-AMINE | AstaTech | 1402576-61-7 | MFCD28133454 | 212.175 | C10H7F3N2 | 95.000 | Nc1cnc2cc(ccc2c1)C(F)(F)F | 1g | 261435877
Medchemexpress LLC Terbinafine | 91161-71-6 | MFCD00242672 | 99.96% | 291.43 | 500 MG
Terbinafine (TDT 067) is an orally active and potent antifungal agent. It is a potent non-competitive inhibitor of squalene epoxidase from Candida, with a Ki of 30 nM. Terbinafine also demonstrates antibacterial activity against certain Gram-positive and Gram-negative bacteria. It is a click chemistry reagent that contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
- Orally active.
- Potent antifungal agent.
- Potent non-competitive inhibitor of squalene epoxidase.
- Shows antibacterial activity against certain gram-positive and gram-negative bacteria.
- Click chemistry reagent.
- Contains an alkyne group.
- Can undergo copper-catalyzed azide-alkyne cycloaddition with molecules containing azide groups.
Medchemexpress LLC 2-iminothiolane hydrochloride | 4781-83-3 | MFCD00039013 | 99.9% | 137.63 | C4H8ClNS | 10 MG
2-Iminothiolane hydrochloride is a thiolating reagent used to introduce sulfhydryl (-SH) groups into primary amines of proteins, peptides, and oligosaccharides. It reacts under near-physiological conditions to expose free thiols for subsequent conjugation, crosslinking, or labeling in bioconjugation workflows.
- Reacts with primary amines at pH 7-10 to generate free thiols.
- Forms an amidine linkage that tethers the thiol to the substrate.
- Enables protein and peptide modification for bioconjugation.
- Suitable for glycan labeling and oligosaccharide modification.
- High purity for reproducible experimental results (>99.9%).
- Solid, white to off-white material that is easy to handle and weigh.
- Available in small research-scale pack sizes for laboratory use.
Sigma Aldrich Fine Chemicals Biosciences o-Phenylenediamine dihydrochloride tablet, 10 mg substrate per tablet | 615-28-1 | MFCD00012966 | 100TAB
o-Phenylenediamine dihydrochloride tablet, 10 mg substrate per tablet | Mol Wt: 181.06 | 615-28-1 | MFCD00012966 | 100TAB
Medchemexpress LLC CP-24879 hydrochlori 10mM 1mL | 10141-51-2 | 1 ML
CP-24879 hydrochloride is a research compound that potently and selectively inhibits delta5 and delta6 desaturases. It is supplied as a 10 mM solution in DMSO (1 mL) for biochemical and cell-based studies of lipid metabolism and inflammatory pathways. CAS 10141-51-2; molecular formula C11H18ClNO; molecular weight 215.72 g·mol⁻¹; reported purity 99.59%.
- Potent dual delta5/delta6 desaturase inhibitor.
- Supplied as a 10 mM solution in DMSO, 1 mL format.
- High reported purity suitable for research use.
- Appropriate for biochemical and cell-based lipid metabolism studies.
- Molecular formula C11H18ClNO; molecular weight 215.72 g·mol⁻¹.
Medchemexpress LLC L-778123 hydrochloride | 253863-00-2 | 99.9% | 442.34 | 50 MG
L-778123 hydrochloride is a dual inhibitor of FPTase and GGPTase-I, with IC50 values of 2 nM and 98 nM respectively. It is intended for research use only.
- Dual inhibitor of FPTase and GGPTase-I.
- Exhibits IC50 values of 2 nM for FPTase and 98 nM for GGPTase-I.
- Alone, it does not show obvious cytotoxicity on HT-29 and A549 cell lines (IC50: >100 μM), but can generate synergistic effects with Doxorubicin.
- Inhibits myeloid leukemia cell proliferation with IC50 values ranging from 0.2 μM to 1.8 μM for cell lines, and 0.1 μM to 161.8 μM in primary samples.
- Inhibits H-RAS prenylation in HL-60 cells and phosphorylated MEK-1/2 levels.
- Inhibits lymphocyte activation and function in human PBMCs.
Medchemexpress LLC Etazolate hydrochloride | 35838-58-5 | MFCD00209848 | 98.0% | 325.79 g/mol | C14H20ClN5O2 | 1 ML
Etazolate hydrochloride is a research-grade small molecule inhibitor of phosphodiesterase 4 (PDE4) and a modulator of GABAA receptors. It is provided as a ready-to-use 10 mM solution in DMSO (1 mL) or as a solid for reconstitution, and is used in neuroscience and pharmacology studies investigating neuroprotection, inflammation, and amyloid precursor protein processing.
- Selective PDE4 inhibitor and GABAA receptor modulator.
- Supplied as a 10 mM solution in DMSO (1 mL) or as solid for reconstitution.
- Purity ≥98.0% as reported by supplier.
- Molecular weight approximately 325.8 g/mol.
- CAS number 35838-58-5 for unambiguous identification.
- Available in small milligram quantities suitable for research use.
- Intended for research applications; not for human or clinical use.