Hydrochlorides
Medchemexpress LLC Dapoxetine hydrochloride | 129938-20-1 | 100.0% | 341.87 | C21H24ClNO | 10 MG
Dapoxetine hydrochloride is the hydrochloride salt of dapoxetine, an orally active selective serotonin reuptake inhibitor (SSRI) used in research on premature ejaculation and serotonin transporter pharmacology. It potently inhibits serotonin uptake and has weaker activity at norepinephrine and dopamine transporters. Supplied as a white to off-white solid with high analytical purity and defined storage recommendations.
- Serotonin transporter (SERT) inhibitor (5-HT uptake IC50 ≈ 1.12 nM)
- Shows measurable norepinephrine and dopamine activity
- High purity suitable for analytical and research use
- White to off-white solid, stable when stored sealed away from moisture
- Available in small mass quantities for laboratory studies
Medchemexpress LLC BRL 52537 hydrochloride | 112282-24-3 | MFCD00672679 | 98.1% | 391.76 g/mol | C18H25Cl3N2O | 100 MG
BRL 52537 hydrochloride is a selective kappa-opioid receptor agonist research compound used to study opioid receptor pharmacology and neuroprotection. It reduces ischemia-evoked nitric oxide production and has demonstrated neuroprotective and antinociceptive effects in preclinical models, making it useful for both in vitro and in vivo neuroscience research.
- Selective kappa-opioid receptor agonist with high affinity.
- Reduces ischemia-evoked nitric oxide production in models.
- Demonstrated neuroprotective and antinociceptive effects.
- Suitable for in vitro and in vivo pharmacology studies.
- High reported purity for research applications.
Selleck Chemical LLC N-Acetyl-5-hydroxytryptamine S2985-5mg
N-Acetyl-5-hydroxytryptamine (NAS N-Acetylserotonin Normelatonin O-Demethylmelatonin) a precursor of melatonin is a potent and selective agonist of TrkB receptor
Medchemexpress LLC Cefotiam hydrochloride | 66309-69-1 | 98.0% | 100 MG
Cefotiam hydrochloride is a parenteral cephalosporin antibiotic that exhibits broad-spectrum activity against both Gram-positive and Gram-negative bacteria. It targets β-lactam and is suitable for various research applications.
- Exhibits antibacterial activity with a MIC value of 1.56 μg/mL for *P. mirabilis* IFO 3849.
- Highly active against *Staph. aureus* (MIC values of 0.5-1 μg/mL) and *Staph. albus* (MICs 0.25-0.5 μg/mL).
- Effective against haemolytic streptococci, pneumococci, and *Streptococcus viridans* with MIC values in the range of 0.06-4 μg/mL.
- Demonstrates in vivo efficacy in curing urinary tract infection with *P. mirabilis* in mice.
Chem-Impex International, Inc. O-Benzyl-hydroxylamine hydrochloride | 2687-43-6 | MFCD00012952 | 5G
O-Benzyl-hydroxylamine hydrochloride, 2687-43-6, MFCD00012952, 5G
Indofine Chemical 4-Phenyl-1,2,3,6-Te, 98%, 1 Gm
4-PHENYL-1,2,3,6-TETRAHYDROPYRIDINE HYDROCHLORIDE 1 GM, Rare Organics & Biochemicals, C11H13N . HCl, MW: 195.69, >98%, 43064-12-6, MFCD00012752
TARGETMOL CHEMICALS INC Duloxetine hydrochloride 100MG
Also available in 1 mL, 10 mg, 50 mg, 200 mg and bulk. Please contact Fisher for quotes. Duloxetine hydrochloride ((S)-Duloxetine hydrochloride) is a thiophene derivative and selective neurotransmitter uptake inhibitor for serotonin and noradrenaline (SNRI). It is an antidepressant agent and anxiolytic, also used for treating pain in patients with diabetes mellitus and fibromyalgia. Purity 99.97%
Medchemexpress LLC TPT-260 Dihydrochloride | 2076-91-7 | 98.0% | 333.32 | 100 MG
TPT-260 Dihydrochloride | 2076-91-7 | 98.0% | 333.32 | 100 MG
Medchemexpress LLC MK2-IN-1 (hydrochloride) | 1314118-94-9 | 98.2% | 509.43 | 10 MG
MK2-IN-1 hydrochloride is a potent and selective MAPKAPK2 (MK2) inhibitor with an IC50 of 0.11 μM for MK2 and an EC50 of 0.35 μM for pHSP27. It impairs the phosphorylation level of serine residues in the Tfcp2l1 protein, making it suitable for studies on protein regulation and cell signaling pathways.
- Increases Tfcp2l1 protein level in mouse embryonic stem cells.
- Induces alkaline phosphatase positive colonies.
- Suitable for in vitro studies with various dissolution protocols.
Medchemexpress LLC ZK756326 dihydrochloride | 1780259-94-0 | MFCD09038571 | 99.9% | 429.38 g/mol | C21H30Cl2N2O3 | 25 MG
ZK756326 dihydrochloride is a small-molecule, nonpeptide agonist of the CC chemokine receptor CCR8 supplied as the dihydrochloride salt for research use only. It is intended for in vitro pharmacology and preclinical studies where modulation of CCR8 signaling is required, and is provided with a defined formula, molecular weight, and high purity.
- Selective CCR8 agonist for receptor pharmacology studies.
- High purity suitable for analytical and biological assays (99.87%).
- Well-defined chemical identity with molecular formula and weight.
- Available in small pack sizes for laboratory research.
- For research use only; not for human or veterinary applications.
Apexbio Technology LLC Doxepin (hydrochloride) 1229-29-4 10mM (in 1mL DMSO)
Doxepin (hydrochloride) (CAS 1229-29-4) is a tricyclic antidepressant that functions as a potent antagonist of the histamine H1 receptor a G protein coupled receptor expressed in tissues such as smooth muscle vascular endothelium cardiac tissue and the central nervous system In vitro doxepin acts as a competitive inhibitor of serotonin uptake in human platelets with a reported Ki of approximately 0 2 M and can induce rapid serotonin efflux at higher concentrations In vivo studies in rodents and canines demonstrate efficient oral absorption and metabolic conversion in liver and urine with central nervous system penetration observed in rats Doxepin is widely used in research related to neurotransmitter modulation and histaminergic signaling
Medchemexpress LLC VU0360172 hydrochloride | 1309976-62-2 | 98.9% | 330.78 g/mol | C18H16ClFN2O | 100 MG
VU0360172 hydrochloride is a potent and selective positive allosteric modulator (PAM) of the metabotropic glutamate receptor 5 (mGlu5), used in pharmacology and neuroscience research to probe mGlu5 signaling. Reported values include EC50 16 nM and Ki 195 nM. The compound is supplied as a white to off-white solid with high purity and recommended cold storage for stability.
- Potent mGlu5 activity (EC50 16 nM).
- Selective binding profile (Ki 195 nM for mGlu5).
- High purity suitable for research use (approximately 98.9%).
- Solid, white to off-white physical form for easy handling.
- Stable when stored cold (recommended -20°C; in solvent: -80°C for extended storage).
- Available in multiple small pack sizes for research workflows.
Medchemexpress LLC Epertinib hydrochloride | 2071195-74-7 | >98.0% | 596.48 g/mol | C30H28Cl2FN5O3 | 1 ML
Epertinib hydrochloride is the hydrochloride salt of epertinib, a reversible and selective tyrosine kinase inhibitor of EGFR, HER2, and HER4 used in oncology research. The product is supplied as a 10 mM solution in DMSO (1 mL) and as solid powders; consult the datasheet and safety information for handling and purity details.
- Potent, reversible inhibitor of EGFR, HER2, and HER4.
- Suitable for in vitro and in vivo oncology research.
- Available as a 10 mM DMSO solution for ready-to-use assays.
- Also available as solid for formulation or long-term storage.
- Molecular weight 596.48 g/mol and CAS number 2071195-74-7.