Hydrochlorides
Medchemexpress LLC ARC 239 dihydrochloride | 55974-42-0 | 99.2% | 10 MG
ARC 239 dihydrochloride is a selective α2B/2C adrenoceptor antagonist with pKd values of 5.95, 7.41, and 7.56 at α2A, α2B, and α2C receptors respectively. It binds to CHO cell membranes expressing human recombinant a2A-, a2B- or a2C-adrenoceptor subtypes with pKis of 5.6, 8.4, and 7.08, respectively. The product is intended for research use only and is not sold to patients.
- Selective α2B/2C adrenoceptor antagonist.
- Binds to human recombinant a2A-, a2B- or a2C-adrenoceptor subtypes.
- Purity: 99.20%.
- Available in various quantities (5 mg, 10 mg, 25 mg, 50 mg, 100 mg, 200 mg).
Medchemexpress LLC AZD-7762 (hydrochloride) | 1246094-78-9 | 98.0 % | 398.88 | 10 MG
AZD-7762 (hydrochloride) | 1246094-78-9 | 98.0 % | 398.88 | 10 MG
Medchemexpress LLC YM-298198 hydrochloride | 1216398-09-2 | MFCD08703122 | ≥99.0% | 378.92 | C18H23ClN4OS | 10 MG
YM-298198 hydrochloride is the hydrochloride salt of a selective, high-affinity, non-competitive antagonist of metabotropic glutamate receptor 1 (mGluR1) supplied for research use in small quantities.
- Selective mGluR1 antagonist with Ki = 19 nM and IC50 = 16 nM in functional assays.
- High reported purity (≥99.0% for latest batches).
- Molecular formula C18H23ClN4OS and molecular weight 378.92.
- CAS number 1216398-09-2 for substance identification.
- Available in small pack sizes such as 10 mg for research applications.
- Recommended storage: -20°C sealed; in solvent: -80°C up to 6 months or -20°C up to 1 month, protected from moisture.
Apexbio Technology LLC RS 127445 HCl 199864-87-4 5mg
RS 127445 HCl (CAS 199864-87-4) is a small-molecule antagonist targeting the serotonin 5-HT2B receptor a member of the G-protein coupled receptor family It is designed to selectively block 5-HT2B receptor activity thereby modulating intracellular signaling pathways such as calcium elevation and inositol phosphate production RS 127445 HCl exerts its biological activity primarily through selective antagonism of the 5-HT2B receptor In isolated tissue preparations such as rat stomach fundus and jugular vein RS 127445 HCl inhibits serotonin-induced contraction Based on these pharmacological properties RS 127445 HCl holds research potential in studies of 5-HT2B receptor function and related physiological processes